{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:16:22Z","timestamp":1763036182371,"version":"3.33.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Supplement 2","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3226,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2006,11]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>\n                                 <jats:bold>Key Concepts:<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>1. Primary sclerosing cholangitis (PSC) in the nontransplant setting is a chronic, progressive liver disease characterized by diffuse stricturing of the biliary tree, cholestatic liver enzymes, and a compatible liver biopsy.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>2. Cholangiography reveals irregularity of the bile duct wall, strictures, beading, and diverticula.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>3. The typical biopsy reveals inflammation and fibrosis of the interlobular and septal bile ducts, often with obliteration or biliary-type cirrhosis.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>4. The precise pathogenetic mechanism remains elusive but is assumed to be an autoimmune phenomenon.<\/jats:bold>\n                              <\/jats:p>\n            <jats:p>\n                                 <jats:bold>5. For patients with end-stage complications of PSC, such as liver failure, recurrent bacterial cholangitis, and intractable pruritus, liver transplantation is an acceptable treatment option. Liver Transpl. 12:S73\u2013S75. 2006. \u00a9 2006 AASLD.<\/jats:bold>\n                              <\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.20948","type":"journal-article","created":{"date-parts":[[2006,10,18]],"date-time":"2006-10-18T21:19:27Z","timestamp":1161206367000},"page":"S73-S75","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":26,"title":["Recurrent primary sclerosing cholangitis: Clinical diagnosis and long-term management issues"],"prefix":"10.1097","volume":"12","author":[{"given":"Fredric","family":"Gordon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-16-20250124","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.2214\/ajr.166.5.8615253","article-title":"Cholangiographic features of biliary strictures after liver transplantation for primary sclerosing cholangitis: evidence of recurrent disease.","volume":"166","author":"Sheng","year":"1996","journal-title":"AJR Am J Roentgenol"},{"key":"R2-16-20250124","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/hep.1840200214","article-title":"Fibrous and obliterative cholangitis in liver allografts: evidence of recurrent primary sclerosing cholangitis.","volume":"20","author":"Harrison","year":"1994","journal-title":"Hepatology"},{"key":"R3-16-20250124","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2214\/ajr.161.2.8333366","article-title":"Biliary strictures in hepatic transplants: prevalence and types in patients with primary sclerosing cholangitis vs those with other liver diseases.","volume":"161","author":"Sheng","year":"1993","journal-title":"AJR Am J Roentgenol"},{"key":"R4-16-20250124","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1002\/hep.510290427","article-title":"Recurrence of primary sclerosing cholangitis after liver transplantation.","volume":"29","author":"Graziadei","year":"1999","journal-title":"Hepatology"},{"key":"R5-16-20250124","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1053\/j.humpath.2003.07.015","article-title":"Liver transplantation for primary sclerosing cholangitis: a longterm clinicopathologic study.","volume":"34","author":"Khettry","year":"2003","journal-title":"Hum Pathol"},{"key":"R6-16-20250124","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1097\/00007890-199811270-00006","article-title":"Recurrent primary sclerosing cholangitis after orthotopic liver transplantation: is chronic rejection part of the disease process?","volume":"66","author":"Jeyarajah","year":"1998","journal-title":"Transplantation"},{"key":"R7-16-20250124","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1016\/S0140-6736(02)11861-7","article-title":"Risk factors for recurrence of primary sclerosing cholangitis of liver allograft.","volume":"360","author":"Vera","year":"2002","journal-title":"Lancet"},{"key":"R8-16-20250124","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1053\/jlts.2003.50143","article-title":"Different immunosuppressive regimens and recurrence of primary sclerosing cholangitis after liver transplantation.","volume":"9","author":"Kugelmas","year":"2003","journal-title":"Liver Transpl"},{"key":"R9-16-20250124","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1002\/lt.20444","article-title":"Recurrent primary sclerosing cholangitis after liver transplantation: a magnetic resonance cholangiography study with analyses of predictive factors.","volume":"11","author":"Brandsaeter","year":"2005","journal-title":"Liver Transpl"},{"key":"R10-16-20250124","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1600-6143.2005.01220.x","article-title":"Improved survival after live donor adult liver transplantation (LDALT) using right lobe grafts: program experience and lessons learned.","volume":"6","author":"Pomposelli","year":"2006","journal-title":"Am J Transpl"},{"key":"R11-16-20250124","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1034\/j.1600-6143.2003.00110.x","article-title":"Denovo cholangiocarcinoma in the setting of recurrent primary sclerosing cholangitis following liver transplant.","volume":"3","author":"Heneghan","year":"2003","journal-title":"Am J Transpl"}],"container-title":["Liver 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