{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T22:06:34Z","timestamp":1790028394042,"version":"4.0.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3106,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2007,3]]},"abstract":"<jats:sec>\n            <jats:title>Abstract<\/jats:title>\n            <jats:p>Liver transplantation can be a therapeutic option for individual patients with neuroendocrine tumors metastatic only to the liver. In this consecutive series of 15 patients (5 multivisceral and 10 orthotopic liver transplantations) with well-differentiated carcinoids, or endocrine pancreatic tumors, we allowed higher proliferation rate (Ki67 &lt;10%), large tumor burden, and higher age than previous studies. Liver transplantation offered good relief of symptoms, long disease-free intervals, and potential cure in individual patients. The survival of grafts and patients compared well with transplantation for benign disease. The overall 5-year survival was 90%. The recurrence-free survival of both multivisceral and liver transplantation related to the time after transplantation (about 20% at 5 years) despite inclusion of patients with higher risk. In conclusion, the critical prognosticators for long-term outcome still remain to be defined. The experience with multivisceral transplantation for patients with endocrine tumors of the pancreatic head is still limited. <jats:italic toggle=\"yes\">Liver Transpl 13:327\u2013333, 2007.<\/jats:italic> \u00a9 2007 AASLD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.21056","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T23:02:53Z","timestamp":1172185373000},"page":"327-333","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":125,"title":["Orthotopic Liver or Multivisceral Transplantation As Treatment of Metastatic Neuroendocrine Tumors"],"prefix":"10.1097","volume":"13","author":[{"given":"Michael","family":"Olausson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Styrbj\u00f6rn","family":"Friman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustaf","family":"Herlenius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Cahlin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ola","family":"Nilsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svante","family":"Jansson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"W\u00e4ngberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5kan","family":"Ahlman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-6-20250124","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.gassur.2003.11.010","article-title":"Liver transplantation for neuroendocrine tumors.","volume":"8","author":"Florman","year":"2004","journal-title":"J Gastrointest Surg"},{"key":"R2-6-20250124","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1002\/lt.20148","article-title":"Liver transplantation for neuroendocrine tumors: progress and uncertainty.","volume":"10","author":"Rosado","year":"2004","journal-title":"Liver Transpl"},{"key":"R3-6-20250124","first-page":"1973","article-title":"Liver transplantation for metastatic neuroendocrine tumors.","volume":"25","author":"Schweizer","year":"1993","journal-title":"Transplant Proc"},{"key":"R4-6-20250124","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1007\/s00268-002-6631-y","article-title":"Indications and results of liver transplantation in patients with neuroendocrine tumors.","volume":"26","author":"Olausson","year":"2002","journal-title":"World J Surg"},{"key":"R5-6-20250124","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1111\/j.1749-6632.1994.tb17301.x","article-title":"Liver transplantation for hepatic metastases of neuroendocrine tumors.","volume":"733","author":"Bechstein","year":"1994","journal-title":"Ann N Y Acad Sci"},{"key":"R6-6-20250124","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/00000658-199704000-00002","article-title":"Liver transplantation for metastatic neuroendocrine tumors.","volume":"225","author":"Lang","year":"1997","journal-title":"Ann Surg"},{"key":"R7-6-20250124","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1097\/00000658-199704000-00003","article-title":"Results of liver transplantation in the treatment of metastatic neuroendocrine tumors. 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