{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:05:24Z","timestamp":1791857124679,"version":"4.3.4"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":3014,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:sec>\n                    <jats:title>Abstract<\/jats:title>\n                    <jats:p>\n                      Liver transplantation (LT) may be indicated in glycogen storage disorders (GSD) when medical treatment fails to control the metabolic problems or when hepatic adenomas develop. We present our institutional experience with living donor LT (LDLT) for children with GSD. A total of 244 patients underwent primary LDLT at our institution from June 1994 to December 2005. A total of 12 (5%) children (8 female and 4 male) were afflicted with GSD and were not responsive to medical treatment. Nine patients had GSD type I and 3 had GSD type III. The median age at the time of transplantation was 7.27 yr (range, 2.4-15.7). All patients presented with metabolic abnormalities, including hypoglycemia, and lactic acidosis. In addition, 4 patients presented with growth retardation. A total of 11 patients received left lobe grafts and 1 received a right lobe graft. The mean graft-to-recipient weight ratio was 1.25 (range, 0.89-1.61). Two patients had hepatic vein stenoses that were treated by balloon dilatation; 1 patient had bile leak, which settled spontaneously. The overall surgical morbidity rate was 25%. Three patients had hepatic adenomas in the explanted liver. There was a single mortality at 2 months posttransplantation due to acute pancreatitis and sepsis. The mean follow up was 47.45 months. The metabolic abnormalities were corrected and renal function remained normal. In patients with growth retardation, catch-up growth was achieved posttransplantation. In conclusion, LDLT is a viable option to restore normal metabolic balance in patients with GSD when medical treatment fails. Long-term follow-up after LT for GSD shows excellent graft and patient survival.\n                      <jats:italic toggle=\"yes\">Liver Transpl 13:848\u2013852, 2007.<\/jats:italic>\n                      \u00a9 2007 AASLD.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/lt.21151","type":"journal-article","created":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T16:47:26Z","timestamp":1180543646000},"page":"848-852","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":46,"title":["Long-Term Results of Living Donor Liver Transplantation for Glycogen Storage Disorders in Children\u2020"],"prefix":"10.1097","volume":"13","author":[{"given":"Shridhar G.","family":"Iyer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao-Long","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Chi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Ho","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan M.","family":"Concejero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueh-Wei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Hsiang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chee-Chien","family":"Yong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Jawan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Fan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hock-Liu","family":"Eng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20260302","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/S0950-3528(98)90138-5","article-title":"Glycogen storage diseases and the liver.","volume":"12","author":"Burchell","year":"1998","journal-title":"Baillieres Clin Gastroenterol"},{"key":"R3-13-20260302","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1023\/A:1005544117285","article-title":"Longterm outcome of liver transplantation in patients with glycogen storage diseases type 1a.","volume":"22","author":"Faivre","year":"1999","journal-title":"J Inherit Metab Dis"},{"key":"R4-13-20260302","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1002\/1097-0142(19920315)69:6<1320::AID-CNCR2820690603>3.0.CO;2-D","article-title":"Type I glycogenosis associated with hepatocellular carcinoma.","volume":"69","author":"Conti","year":"1992","journal-title":"Cancer"},{"key":"R5-13-20260302","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/00004836-200007000-00020","article-title":"Hepatocellular carcinoma complicating liver cirrhosis in type IIIa glycogen storage disease.","volume":"31","author":"Siciliano","year":"2000","journal-title":"J Clin Gastroenterol"},{"key":"R6-13-20260302","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1002\/hep.510250307","article-title":"Type IIIb glycogen storage disease associated with endstage cirrhosis and hepatocellular carcinoma. The Liver Transplant Group.","volume":"25","author":"Haagsma","year":"1997","journal-title":"Hepatology"},{"key":"R7-13-20260302","doi-asserted-by":"crossref","first-page":"2672","DOI":"10.1111\/j.1600-6143.2006.01528.x","article-title":"Living donor liver transplantation for biliary atresia: a singlecenter experience with first 100 cases.","volume":"6","author":"Chen","year":"2006","journal-title":"Am J Transplant"},{"key":"R8-13-20260302","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1600-6143.2006.01618.x","article-title":"Active immunization to prevent de novo hepatitis B virus infection in pediatric live donor liver recipients.","volume":"7","author":"Lin","year":"2007","journal-title":"Am J Transplant"},{"key":"R9-13-20260302","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1203\/00006450-198409000-00015","article-title":"The dietary treatment of children with type I glycogen storage disease with slow release carbohydrate.","volume":"18","author":"Smit","year":"1984","journal-title":"Pediatr Res"},{"key":"R10-13-20260302","first-page":"276","article-title":"Hepatocellular adenomas in glycogen storage disease type I and III: a series of 43 patients and review of the literature.","volume":"24","author":"Labrune","year":"1997","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R11-13-20260302","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/0016-5085(91)90483-2","article-title":"Growth in adulthood after liver transplantation for glycogen storage disease type I.","volume":"101","author":"Kirschner","year":"1991","journal-title":"Gastroenterology"},{"issue":"Suppl 2","key":"R12-13-20260302","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1007\/PL00014320","article-title":"Liver transplantation for glycogen storage disease types I, III, and IV.","volume":"158","author":"Matern","year":"1999","journal-title":"Eur J Pediatr"},{"key":"R13-13-20260302","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0041-1345(02)03951-9","article-title":"Outcome of living donor liver transplantation for glycogen storage disease.","volume":"35","author":"Liu","year":"2003","journal-title":"Transplant Proc"},{"key":"R14-13-20260302","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jss.2005.01.004","article-title":"Is there any difference in anesthetic management of biliary atresia and glycogen storage disease patients undergoing liver transplantation?","volume":"126","author":"Jawan","year":"2005","journal-title":"J Surg Res"},{"key":"R15-13-20260302","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1007\/BF00710057","article-title":"The hepatic glycogen storage diseases-problems beyond childhood.","volume":"18","author":"Lee","year":"1995","journal-title":"J Inherit Metab Dis"},{"key":"R16-13-20260302","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1038\/ki.1989.133","article-title":"Hyperfiltration and renal disease in glycogen storage disease, type I.","volume":"35","author":"Baker","year":"1989","journal-title":"Kidney Int"},{"key":"R17-13-20260302","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/BF01799498","article-title":"The longterm outcome of patients with glycogen storage diseases.","volume":"13","author":"Smit","year":"1990","journal-title":"J Inherit Metab Dis"},{"key":"R18-13-20260302","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1399-0004.1980.tb00136.x","article-title":"Hemorrhagic pancreatitis in a patient with glycogen storage disease type I.","volume":"17","author":"Michels","year":"1980","journal-title":"Clin Genet"},{"key":"R19-13-20260302","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1007\/BF01955007","article-title":"Chronic pancreatitis in a child with glycogen storage disease type I.","volume":"150","author":"Kikuchi","year":"1991","journal-title":"Eur J Pediatr"}],"container-title":["Liver Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.21151","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01445473-200706000-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T16:00:44Z","timestamp":1772467244000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01445473-200706000-00013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1002\/lt.21151","relation":{},"ISSN":["1527-6465"],"issn-type":[{"value":"1527-6465","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}