{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T04:41:44Z","timestamp":1792730504454,"version":"4.5.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":2191,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2009,9]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>Grafts from donation after cardiac death (DCD) donors are used to increase the number of organs available for liver transplantation. There is concern that warm ischemia may impair graft function. We compared our DCD recipients with a case-matched group of donation after brain death (DBD) recipients. Between January 2002 and April 2008, 39 DCD grafts were transplanted. These were matched with 39 DBD recipients on the basis of identified variables that had a significant impact on mortality. These were used to individually match DCD and DBD patients with similar predictive mortality. We compared patient\/graft survival, primary non-function (PNF), and rates of complications. Of all liver transplants, 6.1% were DCD grafts. PNF occurred twice in the DCD group. The incidence of nonanastomotic biliary strictures (NABS; 20.5% versus 0%, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.005) and hepatic artery stenosis (HAS; 12.8% versus 0%, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.027) in the DCD group was higher. One-year (79.5% versus 97.4%, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.029) and 3-year (63.6% versus 97.4%, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.001) graft survival was lower in the DCD group. Three-year patient survival was also lower (68.2% versus 100%, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.0001). Our study is the first to use case-matched patients and compare groups with similar predictive mortality. There was a higher incidence of NABS and HAS in the DCD group. NABS were likely a result of warm ischemia. HAS may have been due to ischemia or arterial injury during retrieval. The DCD group had significantly poorer outcomes, but DCD grafts remain a valuable resource. With careful donor\/recipient selection, minimization of ischemia, and good postoperative care, acceptable results can be achieved.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.21853","type":"journal-article","created":{"date-parts":[[2009,8,28]],"date-time":"2009-08-28T13:12:29Z","timestamp":1251465149000},"page":"1072-1082","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":138,"title":["Liver transplantation following donation after cardiac death: An analysis using matched pairs"],"prefix":"10.1097","volume":"15","author":[{"given":"James K.","family":"Pine","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amer","family":"Aldouri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alistair L.","family":"Young","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mervyn H.","family":"Davies","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdy","family":"Attia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giles J.","family":"Toogood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen G.","family":"Pollard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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