{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T01:30:09Z","timestamp":1789608609081,"version":"build-2803163510"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2011,5,26]],"date-time":"2011-05-26T00:00:00Z","timestamp":1306368000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2011,6]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>Retransplantation is the only therapy for patients who have a failing liver graft, and it can be technically challenging. Although duct-to-duct (DD) biliary reconstruction is considered standard in deceased donor orthotopic whole organ liver transplantation, Roux-en-Y (RY) choledochojejunostomy is preferred by most for biliary reconstruction in retransplantation. We performed a retrospective review of 128 patients who underwent retransplantation after a first transplant with DD biliary construction. Of these 128 patients, 83 had DD biliary reconstructions, and 45 had RY biliary reconstructions. Log-rank tests were used to compare the complication rates between the DD and RY groups, whereas multivariate Cox proportional hazards models were used to compare patient and graft survival between the groups. The median Model for End-Stage Liver Disease score at retransplantation was significantly higher in the DD group (27 versus 21, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.005). The median length of follow-up was 3.3 years. The biliary complication rates were 7% and 11% in the DD group and 10% and 10% in the RY group 30 days and 1 year after retransplantation, respectively (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.73). The rates of primary graft nonfunction complications, hepatic artery thrombosis complications, and reoperation did not differ significantly between groups (all <jats:italic toggle=\"yes\">P<\/jats:italic> \u2265 0.37). In comparison with RY reconstruction, there was no evidence of a difference in patient survival (relative risk = 0.79, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.47) or graft survival (relative risk = 0.94, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.85) for patients with DD reconstruction in multivariate analysis. In conclusion, our results provide evidence that DD biliary reconstruction is feasible in liver retransplantation without increased rates of biliary complications or compromised patient and graft survival. Further studies with larger sample sizes are needed. Liver Transpl 710-716, 2011. \u00a9 2011 AASLD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.22263","type":"journal-article","created":{"date-parts":[[2011,1,14]],"date-time":"2011-01-14T16:32:14Z","timestamp":1295022734000},"page":"710-716","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["A single-center experience with biliary reconstruction in retransplantation: Duct-to-duct or roux-en-Y choledochojejunostomy"],"prefix":"10.1097","volume":"17","author":[{"given":"Lena","family":"Sibulesky","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael G.","family":"Heckman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana K.","family":"Perry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Burcin C.","family":"Taner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darrin L.","family":"Willingham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin H.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-13-20250124","doi-asserted-by":"crossref","first-page":"962970","DOI":"10.1016\/j.jhep.2010.06.006","article-title":"Retransplantation in patients with hepatitis C recurrence after liver transplantation.","volume":"53","author":"Carrion","year":"2010","journal-title":"J Hepatol"},{"key":"R3-13-20250124","doi-asserted-by":"crossref","first-page":"217224","DOI":"10.1111\/j.1477-2574.2010.00162.x","article-title":"Liver retransplantation in adults: a singlecentre, 25year experience.","volume":"12","author":"Marudanayagam","year":"2010","journal-title":"HPB (Oxford)"},{"key":"R4-13-20250124","doi-asserted-by":"crossref","first-page":"884890","DOI":"10.1097\/TP.0b013e3181b6f20e","article-title":"Liver retransplantation of more than two grafts for recurrent failure.","volume":"88","author":"Akpinar","year":"2009","journal-title":"Transplantation"},{"key":"R5-13-20250124","doi-asserted-by":"crossref","first-page":"810813","DOI":"10.1007\/s11605-008-0565-0","article-title":"Choledochocholedochostomy in deceased donor liver transplantation.","volume":"13","author":"Nissen","year":"2009","journal-title":"J Gastrointest Surg"},{"key":"R6-13-20250124","first-page":"264272","article-title":"Management of biliary complications in the liver transplant patient.","volume":"6","author":"Ostroff","year":"2010","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"R7-13-20250124","doi-asserted-by":"crossref","first-page":"107115","DOI":"10.1016\/j.gastrohep.2010.05.008","article-title":"Current management of biliary complications after liver transplantation: emphasis on endoscopic therapy.","volume":"34","author":"Balderramo","year":"2011","journal-title":"Gastroenterol Hepatol"},{"key":"R8-13-20250124","doi-asserted-by":"crossref","first-page":"359371","DOI":"10.1016\/j.cld.2010.03.008","article-title":"Endoscopic management of biliary complications after liver transplantation.","volume":"14","author":"Krok","year":"2010","journal-title":"Clin Liver Dis"},{"key":"R10-13-20250124","doi-asserted-by":"crossref","first-page":"517520","DOI":"10.1016\/j.transproceed.2010.01.017","article-title":"Biliary complications following deceased and living donor liver transplantation: a review.","volume":"42","author":"Duailibi","year":"2010","journal-title":"Transplant Proc"},{"key":"R11-13-20250124","doi-asserted-by":"crossref","first-page":"245257","DOI":"10.1159\/000144653","article-title":"Biliary tract complications after liver transplantation: a review.","volume":"25","author":"Wojcicki","year":"2008","journal-title":"Dig 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Surg"},{"key":"R15-13-20250124","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1016\/j.jhep.2005.05.003","article-title":"What is the best technique for right hemiliver living donor liver transplantation? With or without the middle hepatic vein? Ducttoduct biliary anastomosis or RouxenY hepaticojejunostomy?","volume":"43","author":"Liu","year":"2005","journal-title":"J Hepatol"},{"key":"R16-13-20250124","doi-asserted-by":"crossref","first-page":"17611765","DOI":"10.1002\/lt.21599","article-title":"Biliary reconstruction for infantile living donor liver transplantation: RouxenY hepaticojejunostomy or ducttoduct choledochocholedochostomy?","volume":"14","author":"Shirouzu","year":"2008","journal-title":"Liver Transpl"},{"key":"R17-13-20250124","doi-asserted-by":"crossref","first-page":"379385","DOI":"10.1111\/j.1600-6143.2005.01173.x","article-title":"Surgical complications and longterm outcome of different biliary reconstructions in liver transplantation for primary sclerosing cholangitischoledochoduodenostomy versus choledochojejunostomy.","volume":"6","author":"Schmitz","year":"2006","journal-title":"Am J Transplant"},{"key":"R18-13-20250124","doi-asserted-by":"crossref","first-page":"10221025","DOI":"10.1007\/s00268-008-9885-1","article-title":"Choledochoduodenostomy is a safe alternative to RouxenY choledochojejunostomy for biliary reconstruction in liver transplantation.","volume":"33","author":"Bennet","year":"2009","journal-title":"World J Surg"},{"key":"R19-13-20250124","doi-asserted-by":"crossref","first-page":"18421845","DOI":"10.1097\/TP.0b013e3181a6bb5e","article-title":"Hepaticoduodenostomy is an alternative to RouxenY hepaticojejunostomy for biliary reconstruction in live donor liver transplantation.","volume":"87","author":"Campsen","year":"2009","journal-title":"Transplantation"}],"container-title":["Liver Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.22263","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.22263","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01445473-201106000-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T17:09:20Z","timestamp":1737738560000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01445473-201106000-00013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1002\/lt.22263","relation":{},"ISSN":["1527-6465"],"issn-type":[{"value":"1527-6465","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6]]}}}