{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:24:01Z","timestamp":1763036641051,"version":"3.33.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2012,1,25]],"date-time":"2012-01-25T00:00:00Z","timestamp":1327449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2012,2]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>The demographics of patients in the United States who undergo living donor liver transplantation (LDLT) versus patients who undergo deceased donor liver transplantation (DDLT) are interesting with respect to the demographics of the donor service areas (DSAs). We examined adult recipients of primary, non\u2013status 1 liver-only transplants from 2003 to 2009. The likelihood of undergoing LDLT was compared to the likelihood of undergoing DDLT by multivariate logistic regression. We examined the adjusted odds ratio (OR) for undergoing LDLT versus DDLT for patients with the same diagnosis and blood type after we stratified the DSAs into quintiles by the median match Model for End-Stage Liver Disease (MELD) scores. LDLT was performed for 1497 of 32,927 liver transplants (4.5%). LDLT decreased in frequency by approximately 30% from 2003 to 2009. In comparison with DDLT recipients, LDLT recipients were younger and had higher albumin levels, lower body mass indices, and lower match MELD scores. Females had increased odds of LDLT in comparison with males (OR = 1.74, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). Patients with MELD exception scores were less likely to undergo LDLT (OR = 0.22, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). Patients with cholestatic liver disease (adjusted OR = 2.04, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001) or malignant neoplasms other than hepatocellular carcinoma (adjusted OR = 3.33, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001) were more likely than patients with hepatitis C virus to undergo LDLT. Other characteristics associated with decreased odds of LDLT were black race (adjusted OR = 0.41, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001) and government insurance (adjusted OR = 0.51, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). LDLT was more frequent in DSAs with high median MELD scores; the adjusted OR for LDLT was 38 for the DSAs in the highest quintile (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). In conclusion, there are significant differences associated with race, insurance, sex, MELD exceptions, and DSA MELD scores between patients who undergo LDLT and patients who undergo DDLT. These differences can be hypothesized to be driven in part by the relative availability of LDLT versus DDLT at both the patient level and the DSA level. Liver Transpl 18:160\u2013165, 2012. \u00a9 2011 AASLD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.22455","type":"journal-article","created":{"date-parts":[[2011,10,17]],"date-time":"2011-10-17T15:53:59Z","timestamp":1318866839000},"page":"160-165","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":29,"title":["Use of living donor liver transplantation varies with the availability of deceased donor liver transplantation"],"prefix":"10.1097","volume":"18","author":[{"given":"Parsia A.","family":"Vagefi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy L.","family":"Ascher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chris E.","family":"Freise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jennifer L.","family":"Dodge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John P.","family":"Roberts","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-4-20250124","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1056\/NEJM199005243222106","article-title":"Successful liver transplantation from a living donor to her son.","volume":"322","author":"Strong","year":"1990","journal-title":"N Engl J Med"},{"key":"R2-4-20250124","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1053\/j.gastro.2007.09.004","article-title":"; for A2ALL Study Group. Improvement in survival associated with adulttoadult living donor liver transplantation.","volume":"133","author":"Berg","year":"2007","journal-title":"Gastroenterology"},{"key":"R3-4-20250124","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1002\/lt.20227","article-title":"Fulminant and fatal gas gangrene of the stomach in a healthy live liver donor.","volume":"10","author":"Miller","year":"2004","journal-title":"Liver Transpl"},{"key":"R4-4-20250124","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1002\/lt.20024","article-title":"Results of the first year of the new liver allocation plan.","volume":"10","author":"Freeman","year":"2004","journal-title":"Liver Transpl"},{"issue":"pt 2","key":"R5-4-20250124","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1111\/j.1600-6143.2009.02567.x","article-title":"Liver and intestine transplantation in the United States 1998-2007.","volume":"9","author":"Berg","year":"2009","journal-title":"Am J Transplant"},{"key":"R6-4-20250124","doi-asserted-by":"crossref","first-page":"2371","DOI":"10.1001\/jama.2008.720","article-title":"Disparities in liver transplantation before and after introduction of the MELD score.","volume":"300","author":"Moylan","year":"2008","journal-title":"JAMA"},{"key":"R7-4-20250124","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1002\/lt.22121","article-title":"Gender disparity in liver transplant waitinglist mortality: the importance of kidney function.","volume":"16","author":"Mindikoglu","year":"2010","journal-title":"Liver Transpl"},{"key":"R8-4-20250124","doi-asserted-by":"crossref","first-page":"2658","DOI":"10.1111\/j.1600-6143.2010.03326.x","article-title":"Height contributes to the gender difference in waitlist mortality under the MELDbased liver allocation system.","volume":"10","author":"Lai","year":"2010","journal-title":"Am J Transplant"},{"key":"R9-4-20250124","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1002\/lt.22002","article-title":"Genderspecific differences associated with living donor liver transplantation: a review study.","volume":"16","author":"Hermann","year":"2010","journal-title":"Liver Transpl"},{"key":"R10-4-20250124","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/TP.0b013e3182066275","article-title":"Geographic inequity in access to livers for transplantation.","volume":"91","author":"Yeh","year":"2011","journal-title":"Transplantation"},{"key":"R11-4-20250124","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1002\/hep.24494","article-title":"Liver transplant recipient survival benefit with living donation in the Model for Endstage Liver Disease allocation era.","volume":"54","author":"Berg","year":"2011","journal-title":"Hepatology"}],"container-title":["Liver Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.22455","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.22455","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01445473-201202000-00004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T17:14:59Z","timestamp":1737738899000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01445473-201202000-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1002\/lt.22455","relation":{},"ISSN":["1527-6465"],"issn-type":[{"type":"print","value":"1527-6465"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}