{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T22:34:41Z","timestamp":1792017281716,"version":"4.4.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":853,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,5]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>The incidence of morbidity and mortality after living donor liver transplantation (LDLT) is not well understood because reporting is not standardized and relies on single-center reports. Aborted hepatectomies (AHs) and potentially life-threatening near-miss events (during which a donor's life may be in danger but after which there are no long-term sequelae) are rarely reported. We conducted a worldwide survey of programs performing LDLT to determine the incidence of these events. A survey instrument was sent to 148 programs performing LDLT. The programs were asked to provide donor demographics, case volumes, and information about graft types, operative morbidity and mortality, near-miss events, and AHs. Seventy-one programs (48%), which performed donor hepatectomy 11,553 times and represented 21 countries, completed the survey. The average donor morbidity rate was 24%, with 5 donors (0.04%) requiring transplantation. The donor mortality rate was 0.2% (23\/11,553), with the majority of deaths occurring within 60 days, and all but 4 deaths were related to the donation surgery. The incidences of near-miss events and AH were 1.1% and 1.2%, respectively. Program experience did not affect the incidence of donor morbidity or mortality, but near-miss events and AH were more likely in low-volume programs (\u226450 LDLT procedures). In conclusion, it appears that independently of program experience, there is a consistent donor mortality rate of 0.2% associated with LDLT donor procedures, yet increased experience is associated with lower rates of AH and near-miss events. Potentially life-threatening near-miss events and AH are underappreciated complications that must be discussed as part of the informed consent process with any potential living liver donor. <jats:italic toggle=\"yes\">Liver Transpl 19:499\u2013506, 2013<\/jats:italic>. \u00a9 2012 AASLD.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1002\/lt.23575","type":"journal-article","created":{"date-parts":[[2012,11,21]],"date-time":"2012-11-21T20:11:18Z","timestamp":1353528678000},"page":"499-506","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":247,"title":["Incidence of death and potentially life-threatening near-miss events in living donor hepatic lobectomy"],"prefix":"10.1097","volume":"19","author":[{"given":"Yee Lee","family":"Cheah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ann","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James J.","family":"Pomposelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Pomfret","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-5-20250124","doi-asserted-by":"crossref","first-page":"589598","DOI":"10.1111\/j.1600-6143.2005.01220.x","article-title":"Improved survival after live donor adult liver transplantation (LDALT) using right lobe grafts: program experience and lessons learned.","volume":"6","author":"Pomposelli","year":"2006","journal-title":"Am J Transplant"},{"issue":"pt 2","key":"R2-5-20250124","first-page":"13761389","article-title":"Liver and intestine transplantation in the United States, 19962005.","volume":"7","author":"Pomfret","year":"2007","journal-title":"Am J Transplant"},{"key":"R4-5-20250124","doi-asserted-by":"crossref","first-page":"428437","DOI":"10.1097\/00000658-199110000-00007","article-title":"Liver transplantation in children from living related donors. Surgical techniques and results.","volume":"214","author":"Broelsch","year":"1991","journal-title":"Ann Surg"},{"key":"R5-5-20250124","doi-asserted-by":"crossref","first-page":"920927","DOI":"10.1002\/lt.20734","article-title":"Lessons learned from 1,000 living donor liver transplantations in a single center: how to make living donations safe.","volume":"12","author":"Hwang","year":"2006","journal-title":"Liver Transpl"},{"key":"R7-5-20250124","doi-asserted-by":"crossref","first-page":"358360","DOI":"10.1097\/01.TP.0000046527.19422.3E","article-title":"Hepatic venoplasty in livingdonor liver transplantation using right lobe graft with middle hepatic vein.","volume":"75","author":"Lo","year":"2003","journal-title":"Transplantation"},{"key":"R8-5-20250124","doi-asserted-by":"crossref","first-page":"13731385","DOI":"10.1097\/01.tp.0000216825.56841.cd","article-title":"A report of the Vancouver Forum on the care of the live organ donor: lung, liver, pancreas, and intestine data and medical guidelines.","volume":"81","author":"Barr","year":"2006","journal-title":"Transplantation"},{"key":"RU9-5-20250124","doi-asserted-by":"crossref","first-page":"613624","DOI":"10.1016\/S0168-8278(01)00031-9","article-title":"Live donor liver transplantation.","volume":"34","author":"Pomfret","year":"2001","journal-title":"J Hepatol"},{"key":"RU10-5-20250124","first-page":"36203621","article-title":"Living related liver transplantation: 36 cases at the University of Hamburg.","volume":"26","author":"Malago","year":"1994","journal-title":"Transplant Proc"},{"key":"R11-5-20250124","doi-asserted-by":"crossref","first-page":"13151319","DOI":"10.1002\/lt.20227","article-title":"Fulminant and fatal gas gangrene of the stomach in a healthy live liver donor.","volume":"10","author":"Miller","year":"2004","journal-title":"Liver Transpl"},{"key":"RU12-5-20250124","doi-asserted-by":"crossref","first-page":"154156","DOI":"10.1002\/lt.21002","article-title":"Acute myocardial infarction after live 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Health man succumbs, gives life to halfbrother. p. A1. News Observer.","volume":"1999","author":"Zagier","year":"3","journal-title":"October"},{"key":"R28-5-20250124","doi-asserted-by":"crossref","first-page":"853862","DOI":"10.1097\/01.sla.0000098619.71694.74","article-title":"Right living donor liver transplantation: an option for adult patients: single institution experience with 74 patients.","volume":"238","author":"Malago","year":"2003","journal-title":"Ann Surg"},{"key":"RU29-5-20250124","doi-asserted-by":"crossref","first-page":"411424","DOI":"10.1055\/s-2000-13153","article-title":"Adulttoadult livingdonor liver transplantation: a critical analysis.","volume":"20","author":"Renz","year":"2000","journal-title":"Semin Liver Dis"},{"key":"R31-5-20250124","doi-asserted-by":"crossref","first-page":"14851488","DOI":"10.1002\/lt.20875","article-title":"Documented deaths of hepatic lobe donors for living donor liver transplantation.","volume":"12","author":"Trotter","year":"2006","journal-title":"Liver Transpl"},{"key":"R32-5-20250124","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1002\/lt.20835","article-title":"Live liver donor mortality.","volume":"12","author":"Chan","year":"2006","journal-title":"Liver Transpl"},{"key":"R33-5-20250124","doi-asserted-by":"crossref","first-page":"11281137","DOI":"10.1056\/NEJMsa012337","article-title":"Hospital volume and surgical mortality in the United States.","volume":"346","author":"Birkmeyer","year":"2002","journal-title":"N Engl J Med"},{"key":"R34-5-20250124","doi-asserted-by":"crossref","first-page":"21172127","DOI":"10.1056\/NEJMsa035205","article-title":"Surgeon volume and operative mortality in the United States.","volume":"349","author":"Birkmeyer","year":"2003","journal-title":"N Engl J Med"},{"key":"R35-5-20250124","doi-asserted-by":"crossref","first-page":"425433","DOI":"10.1001\/archsurg.136.4.425","article-title":"Live donor adult liver transplantation using right lobe grafts: donor evaluation and surgical outcome.","volume":"136","author":"Pomfret","year":"2001","journal-title":"Arch Surg"},{"key":"R36-5-20250124","doi-asserted-by":"crossref","first-page":"832838","DOI":"10.1111\/j.1600-6143.2007.02135.x","article-title":"Successful algorithm for selective liver biopsy in the right hepatic lobe live donor (RHLD).","volume":"8","author":"Simpson","year":"2008","journal-title":"Am J Transplant"},{"key":"R37-5-20250124","doi-asserted-by":"crossref","first-page":"17551756","DOI":"10.1111\/j.1600-6143.2006.01426.x","article-title":"Striving for perfection: evaluation of the right lobe live liver donor.","volume":"6","author":"Pomfret","year":"2006","journal-title":"Am J Transplant"},{"key":"R39-5-20250124","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.1093\/bmb\/ldq003","article-title":"Livingdonor liver transplantation in adults.","volume":"94","author":"Lee","year":"2010","journal-title":"Br Med Bull"},{"key":"R40-5-20250124","doi-asserted-by":"crossref","first-page":"421423","DOI":"10.1016\/j.transproceed.2010.01.012","article-title":"Surgical complications in 100 donor hepatectomies for living donor liver transplantation in a single Brazilian center.","volume":"42","author":"Fernandes","year":"2010","journal-title":"Transplant Proc"}],"container-title":["Liver Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.23575","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01445473-201305000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,24]],"date-time":"2025-01-24T17:28:29Z","timestamp":1737739709000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01445473-201305000-00005"}},"subtitle":["A world-wide survey"],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1002\/lt.23575","relation":{},"ISSN":["1527-6465"],"issn-type":[{"value":"1527-6465","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}