{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T22:24:51Z","timestamp":1787869491909,"version":"build-2784847793"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>Improved outcomes have been shown in liver transplantation (LT) with portal vein thrombosis (PVT). However, PVT is still discovered incidentally during surgery despite careful preoperative imaging. Data are limited comparing the outcomes of incidental PVT with PVT diagnosed via preoperative imaging before LT. This study aims to compare the overall outcomes of patients with PVT. From 2008 to 2012, 369 patients had LT, and 58 patients with PVT were identified. They were divided into those with non\u2010PVT (group 0; n\u2009=\u2009311), preoperatively identified PVT (group 1; n\u2009=\u200928), and incidental PVT (group 2; n\u2009=\u200930). The demographics, characteristics, preoperative assessment, and postoperative outcomes were compared. A survival analysis was also performed. Baseline characteristics and preoperative evaluations of all 3 groups were comparable (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009&gt;\u20090.05) except for Model for End\u2010Stage Liver Disease score, tumor status, platelet levels, and serum bilirubin. A multivariate analysis only showed a high serum bilirubin level to be a predictor of PVT (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.004; odds ratio, 3.395; 95% confidence interval, 1.467\u20107.861). Postoperative outcomes were also comparable (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009&gt;\u20090.05). Compared to group 2, group 1 had more patients with a Yerdel classification of 3 or 4 with more extensive surgical intervention required (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.02). The survival analysis in all 3 groups was comparable with 5\u2010year survival rate of 87.4%, 84.6%, and 91.8% in group 0, 1, and 2, respectively (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.66). In conclusion, recipients with PVT undergoing LT can have similar outcomes as the non\u2010PVT patients even if PVTs were discovered incidentally. Discovery of incidental PVT only requires thrombectomy with no substantial change of treatment strategy, and the outcome is not adversely affected because most incidental PVTs are of a lower Yerdel grade. Preoperative imaging is useful to identify those with a higher Yerdel grade to allow planning of surgical strategy during transplantation.<jats:italic toggle=\"yes\">Liver Transpl 21:944\u2010952, 2015<\/jats:italic>. \u00a9 2015 AASLD.<\/jats:p>","DOI":"10.1002\/lt.24149","type":"journal-article","created":{"date-parts":[[2015,4,17]],"date-time":"2015-04-17T22:35:39Z","timestamp":1429310139000},"page":"944-952","source":"Crossref","is-referenced-by-count":21,"title":["The friendly incidental portal vein thrombus in liver transplantation"],"prefix":"10.1097","volume":"21","author":[{"given":"Peng Soon","family":"Koh","sequence":"first","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"See Ching","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth Siu\u2010Ho","family":"Chok","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William Wei","family":"Sharr","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany Cho-Lam","family":"Wong","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sui Ling","family":"Sin","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chung Mau","family":"Lo","sequence":"additional","affiliation":[{"name":"Division of Liver Transplantation, Department of Surgery, Queen Mary Hospital,The University of Hong Kong,Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2015,6,26]]},"reference":[{"key":"lt24149-bib-0001-20240115","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1002\/hep.1840020517","article-title":"Liver transplantation in adults","volume":"2","year":"1982","journal-title":"Hepatology"},{"key":"lt24149-bib-0002-20240115","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1097\/00007890-200005150-00023","article-title":"Portal vein thrombosis in adults undergoing liver transplantation: risk factors, screening, management, and 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