{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T06:31:22Z","timestamp":1787725882428,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","license":[{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,6,26]],"date-time":"2015-06-26T00:00:00Z","timestamp":1435276800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:p>Early hepatic venous outflow obstruction (HVOO) can be a devastating complication leading to graft loss after liver transplantation (LT). A retrospective study on 777 adult LT recipients over a 5\u2010year period (August 2007 to August 2012) was undertaken to determine the incidence of early HVOO presenting within 3 months of transplant, its clinical features and management, and potential technical risk factors related to the implanting technique. Cases of early HVOO were screened for by identifying recipients with problematic ascites within 3 months of transplant. Definitive diagnosis for HVOO was based on a wedge pressure of &gt;12 mm Hg. Considering only whole livers, the incidence of early problematic ascites was 3% (20\/695) of which more than one\u2010third (35%, 7\/20) were then confirmed to have HVOO. Overall, the incidence of early HVOO was 1% (7\/695). Two hepatic veins (HVs) with extension piggybacks (PBs; n\u2009=\u2009423) were the dominant implanting technique in the time period of study rather than the 3 HV PB (n\u2009=\u2009182) and caval replacement techniques (n\u2009=\u200982). Considering the implantation technique, all cases of HVOO occurred after 2 HVs when extension PBs had been used with an incidence of 1.7% (7\/423). Institutionally, early HVOO was mainly managed surgically by either cavoplasty within a month of transplant (n\u2009=\u20094) or retransplant (n\u2009=\u20091), and the remainder (n\u2009=\u20092) were medically managed with diuretics. In conclusion, early HVOO is rare, and there is no evidence from this study that a given implantation technique is at a higher risk of developing HVOO (2 HV with extension versus 3 HV and caval replacement;<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.11). However, early revisional surgery for HVOO can preserve graft function with retransplantation being reserved for when surgical cavoplasty or radiological stenting is technically not possible.<jats:italic toggle=\"yes\">Liver Transpl 21:914\u2010921, 2015<\/jats:italic>. \u00a9 2015 AASLD.<\/jats:p>","DOI":"10.1002\/lt.24154","type":"journal-article","created":{"date-parts":[[2015,4,23]],"date-time":"2015-04-23T05:23:16Z","timestamp":1429766596000},"page":"914-921","source":"Crossref","is-referenced-by-count":24,"title":["Presentation, diagnosis, and management of early hepatic venous outflow complications in whole cadaveric liver transplant"],"prefix":"10.1097","volume":"21","author":[{"given":"Shirin Elizabeth","family":"Khorsandi","sequence":"first","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuja","family":"Athale","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Vilca\u2010Melendez","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayel","family":"Jassem","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Prachalias","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parthi","family":"Srinivasan","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Rela","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Heaton","sequence":"additional","affiliation":[{"name":"Institute of Liver Studies,King's College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2015,6,26]]},"reference":[{"key":"lt24154-bib-0001-20240115","first-page":"659","article-title":"Homotransplantation of the liver in humans","volume":"117","year":"1963","journal-title":"Surg Gynecol Obstet"},{"key":"lt24154-bib-0002-20240115","first-page":"535","article-title":"Liver transplantation in man","volume":"4","year":"1968","journal-title":"I. 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