{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T12:11:13Z","timestamp":1777637473442,"version":"3.51.4"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T00:00:00Z","timestamp":1435881600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T00:00:00Z","timestamp":1435881600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>\n                           <jats:italic toggle=\"yes\">Echinococcus alveolaris<\/jats:italic> (EA) causes a hepatic zoonotic infection and behaves like a malignant tumor during invasion. Liver transplantation (LT) is the only curative treatment option for this unresectable disease. Here, we share our experience with living donor liver transplantation (LDLT) due to EA from the time between March 2002 and November 2014 at the Liver Transplantation Institute of \u0130n\u00f6n\u00fc University. Ten patients (mean age, 38.6 years) undergoing LDLT because of unresectable EA were evaluated preoperatively, and the operative and follow\u2010up data were analyzed retrospectively. The mean time interval between diagnosis and LT was 27 months. The mean operation time and mean intraoperative blood requirement were 613 minutes and 4 units of packed red blood cells, respectively. Diaphragmatic resections were performed in 3 patients, and vena cava replacement was performed in 2 patients because of difficulties in removing the extended disease. The local recurrence and distant metastasis rates were 10% and 20%, respectively. The mean survival time was 19.5 months (range, 0\u201054 months), and the mortality rate was 30%. Unresectable hepatic alveolar echinococcosis is a rare indication for LT and presents some technical difficulties during surgery because diaphragmatic resection, vascular reconstruction, or multiple blood transfusions may be needed. LDLT can be performed successfully in patients with this rare infectious disease, with careful follow\u2010up for potential recurrence and metastasis and administration of low\u2010dose immunosuppressive agents. <jats:italic toggle=\"yes\">Liver Transpl 21:1091\u20101095, 2015<\/jats:italic>. \u00a9 2015 AASLD.<\/jats:p>","DOI":"10.1002\/lt.24170","type":"journal-article","created":{"date-parts":[[2015,5,15]],"date-time":"2015-05-15T16:04:24Z","timestamp":1431705864000},"page":"1091-1095","source":"Crossref","is-referenced-by-count":37,"title":["Living donor liver transplantation for Echinococcus Alveolaris: single\u2010center experience"],"prefix":"10.1097","volume":"21","author":[{"given":"Fatih","family":"Ozdemir","sequence":"first","affiliation":[{"name":"Liver Transplantation Institute, Department of Surgery,\u0130n\u00f6n\u00fc University,Malatya,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volkan","family":"Ince","sequence":"additional","affiliation":[{"name":"Liver Transplantation Institute, Department of Surgery,\u0130n\u00f6n\u00fc University,Malatya,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bora","family":"Barut","sequence":"additional","affiliation":[{"name":"Liver Transplantation Institute, Department of Surgery,\u0130n\u00f6n\u00fc University,Malatya,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asim","family":"Onur","sequence":"additional","affiliation":[{"name":"Liver Transplantation Institute, Department of Surgery,\u0130n\u00f6n\u00fc University,Malatya,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cuneyt","family":"Kayaalp","sequence":"additional","affiliation":[{"name":"Liver Transplantation Institute, Department of Surgery,\u0130n\u00f6n\u00fc University,Malatya,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sezai","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Liver Transplantation Institute, Department of Surgery,\u0130n\u00f6n\u00fc University,Malatya,Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2015,7,3]]},"reference":[{"key":"lt24170-bib-0001-20240115","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1128\/CMR.5.3.248","article-title":"Molecular and immunological diagnosis of echinococcosis","volume":"5","year":"1992","journal-title":"Clin Microbiol Rev"},{"key":"lt24170-bib-0002-20240115","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1097\/00007890-199410150-00008","article-title":"Liver transplantation for Echinococcus granulosis hydatid disease","volume":"58","year":"1994","journal-title":"Transplantation"},{"key":"lt24170-bib-0003-20240115","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1016\/j.transproceed.2005.03.111","article-title":"Orthotopic liver transplantation for incurable alveolar echinococcosis: report of five cases from west China","volume":"37","year":"2005","journal-title":"Transplant Proc"},{"key":"lt24170-bib-0004-20240115","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/00042737-200012030-00011","article-title":"A twenty\u2010year history of alveolar echinococcosis: analysis of a series of 117 patients from eastern France","volume":"12","year":"2000","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"lt24170-bib-0005-20240115","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1097\/01.TP.0000054230.63568.79","article-title":"Experience of liver transplantation for incurable alveolar echinococcosis: a 45\u2010case European collaborative report","volume":"75","year":"2003","journal-title":"Transplantation"},{"key":"lt24170-bib-0006-20240115","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ijscr.2014.01.003","article-title":"Living donor liver transplantation with replacement of vena cava for Echinococcus alveolaris: A case report","volume":"5","year":"2014","journal-title":"Int J Surg Case Rep"},{"key":"lt24170-bib-0007-20240115","first-page":"801657","article-title":"Replacement of vena cava up to the right atrium during living donor liver transplantation for Echinococcus alveolaris","volume":"2014","year":"2014","journal-title":"Case Rep Transplant"},{"key":"lt24170-bib-0008-20240115","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1007\/s00423-003-0394-2","article-title":"Indications and results of liver transplantation for Echinococcus alveolar infection: an overview","volume":"388","year":"2003","journal-title":"Langenbecks Arch Surg"},{"key":"lt24170-bib-0009-20240115","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1002\/lt.22299","article-title":"Should possible recurrence of disease contraindicate liver transplantation in patients with end\u2010stage alveolar echinococcosis? A 20\u2010year follow\u2010up study","volume":"17","year":"2011","journal-title":"Liver Transpl"},{"key":"lt24170-bib-0010-20240115","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1093\/jac\/46.3.451","article-title":"Benzimidazoles in the treatment of alveolar echinococcosis: a comparative study and review of the literature","volume":"46","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"lt24170-bib-0011-20240115","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/hep.20078","article-title":"Structured treatment interruption in patients with alveolar Echinococcosis","volume":"39","year":"2004","journal-title":"Hepatology"},{"key":"lt24170-bib-0012-20240115","doi-asserted-by":"crossref","first-page":"2936","DOI":"10.1016\/j.transproceed.2009.07.022","article-title":"Liver transplantation in management of alveolar echinococcosis: two case reports","volume":"41","year":"2009","journal-title":"Transplant Proc"},{"key":"lt24170-bib-0013-20240115","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1111\/tid.12222","article-title":"A rare reason for liver transplantation: hepatic alveoloar echinococcosis","volume":"16","year":"2014","journal-title":"Transpl Infect Dis"},{"key":"lt24170-bib-0014-20240115","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1016\/j.transproceed.2013.02.084","article-title":"Living donor liver transplantation for alveolar echinococcus is a difficult procedure","volume":"45","year":"2013","journal-title":"Transplant Proc"}],"container-title":["Liver Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.24170","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.24170","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01445473-201508000-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T03:00:34Z","timestamp":1705287634000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01445473-201508000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,3]]},"references-count":14,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.1002\/lt.24170","relation":{},"ISSN":["1527-6465","1527-6473"],"issn-type":[{"value":"1527-6465","type":"print"},{"value":"1527-6473","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,3]]}}}