{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T08:31:35Z","timestamp":1758270695129},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T00:00:00Z","timestamp":1453852800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,1,27]],"date-time":"2016-01-27T00:00:00Z","timestamp":1453852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:p>Extracorporeal membrane oxygenation (ECMO) has been used to support brain\u2010dead donors for liver procurement. This study investigated the potential role of ultrasonographic monitoring of hepatic perfusion as an aid to improve the viability of liver transplants obtained from brain\u2010dead donors who are supported on ECMO. A total of 40 brain\u2010dead patients maintained on ECMO served as the study population. Hepatic blood flow was monitored using ultrasonography, and perioperative optimal perfusion was maintained by calibrating ECMO. Liver function tests were performed to assess the viability of the graft. The hepatic arterial blood flow was well maintained with no significant changes observed before and after ECMO (206\u2009\u00b1\u200932 versus 241\u2009\u00b1\u200945 mL\/minute; <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.06). Similarly, the portal venous blood flow was also maintained throughout (451\u2009\u00b1\u200965 versus 482\u2009\u00b1\u200977 mL\/minute; <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.09). No significant change in levels of total bilirubin, alanine transaminase, and lactic acid were reported during ECMO (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.17, <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.08, and <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.09, respectively). Before the liver is procured, ultrasonographic monitoring of hepatic blood flow could be a valuable aid to improve the viability of a liver transplant by allowing for real\u2010time calibration of ECMO perfusion in brain\u2010dead liver donors. In our study, ultrasonographic monitoring helped prevent warm ischemic injury to the liver graft by avoiding both overperfusion and underperfusion of the liver. <jats:italic toggle=\"yes\">Liver Transpl 22:188\u2010191, 2016<\/jats:italic>. \u00a9 2015 AASLD.<\/jats:p>","DOI":"10.1002\/lt.24318","type":"journal-article","created":{"date-parts":[[2015,9,3]],"date-time":"2015-09-03T23:55:12Z","timestamp":1441324512000},"page":"188-191","source":"Crossref","is-referenced-by-count":5,"title":["Using ultrasonography to monitor liver blood flow for liver transplant from donors supported on extracorporeal membrane oxygenation"],"prefix":"10.1097","volume":"22","author":[{"given":"Xian\u2010Sheng","family":"Zhu","sequence":"first","affiliation":[{"name":"Department of Ultrasound,General Hospital of Guangzhou Military Command of People's Liberation Army,Guangzhou,China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sha\u2010Sha","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ultrasound,General Hospital of Guangzhou Military Command of People's Liberation Army,Guangzhou,China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Ultrasound,General Hospital of Guangzhou Military Command of People's Liberation Army,Guangzhou,China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chuang\u2010Wen","family":"Ye","sequence":"additional","affiliation":[{"name":"Department of Ultrasound,General Hospital of Guangzhou Military Command of People's Liberation Army,Guangzhou,China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Huo","sequence":"additional","affiliation":[{"name":"The Center for Liver Disease and Transplantation, General Hospital of Guangzhou Military Command of People's Liberation Army,Guangzhou,China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Li","sequence":"additional","affiliation":[{"name":"The Center for Liver Disease and Transplantation, General Hospital of Guangzhou Military Command of People's Liberation Army,Guangzhou,China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2016,1,27]]},"reference":[{"key":"lt24318-bib-0001-20240115","first-page":"734","article-title":"Pre\u2010transplant utilization of sorafenib is not associated with increased complications after liver transplantation","volume":"7","year":"2013","journal-title":"Transpl Int"},{"key":"lt24318-bib-0002-20240115","first-page":"673","article-title":"Induction immunosuppression in liver transplantation: a review","volume":"7","year":"2013","journal-title":"Transpl 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