{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:44:58Z","timestamp":1791773098536,"version":"4.3.4"},"reference-count":109,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T00:00:00Z","timestamp":1456358400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2016,2,25]],"date-time":"2016-02-25T00:00:00Z","timestamp":1456358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:p>Portal vein thrombosis (PVT) occurs in approximately 2%\u201026% of the patients awaiting liver transplantation (LT) and is no longer an absolute contraindication for LT. Nearly half of PVT cases are accidentally found during the LT procedure. The most important risk factor for PVT development in cirrhosis may be the severity of liver disease and reduced portal blood flow. Whether other inherited or acquired coagulation disorders also play a role is not yet clear. The development of PVT may have no effect on the liver disease progression, especially when it is nonocclusive. PVT may not increase the risk of wait\u2010list mortality, but it is a risk factor for poor early post\u2010LT mortality. Anticoagulation and transjugular intrahepatic portosystemic shunt (TIPS) are 2 major treatment strategies for patients with PVT on the waiting list. The complete recanalization rate after anticoagulation is approximately 40%. The role of TIPS to maintain PV patency for LT as the primary indication has been reported, but the safety and efficacy should be further evaluated. PVT extension and degree may determine the surgical technique to be used during LT. If a \u201cconventional\u201d end\u2010to\u2010end portal anastomotic technique is used, there is not a major impact on post\u2010LT survival. Post\u2010LT PVT can significantly reduce both graft and patient survival after LT and can preclude future options for re\u2010LT. <jats:italic toggle=\"yes\">Liver Transpl 22:352\u2010365, 2016<\/jats:italic>. \u00a9 2015 AASLD.<\/jats:p>","DOI":"10.1002\/lt.24387","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T08:14:39Z","timestamp":1450512879000},"page":"352-365","source":"Crossref","is-referenced-by-count":114,"title":["Nontumoral portal vein thrombosis in patients awaiting liver transplantation"],"prefix":"10.1097","volume":"22","author":[{"given":"Hui","family":"Chen","sequence":"first","affiliation":[{"name":"Barcelona Hepatic Hemodynamic Laboratory, Liver Unit,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fanny","family":"Turon","sequence":"additional","affiliation":[{"name":"Barcelona Hepatic Hemodynamic Laboratory, Liver Unit,Barcelona,Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas,Madrid,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Hern\u00e1ndez\u2010Gea","sequence":"additional","affiliation":[{"name":"Barcelona Hepatic Hemodynamic Laboratory, Liver Unit,Barcelona,Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas,Madrid,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Fuster","sequence":"additional","affiliation":[{"name":"HBP Surgery and Liver Transplantation Unit,University of Barcelona,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angeles","family":"Garcia\u2010Criado","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Clinic,Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Barrufet","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Clinic,Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Darnell","sequence":"additional","affiliation":[{"name":"Department of Radiology, Hospital Clinic,Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantino","family":"Fondevila","sequence":"additional","affiliation":[{"name":"HBP Surgery and Liver Transplantation Unit,University of Barcelona,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Garcia\u2010Valdecasas","sequence":"additional","affiliation":[{"name":"HBP Surgery and Liver Transplantation Unit,University of Barcelona,Barcelona,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Garcia\u2010Pag\u00e1n","sequence":"additional","affiliation":[{"name":"Barcelona Hepatic Hemodynamic Laboratory, Liver Unit,Barcelona,Spain"},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Enfermedades Hep\u00e1ticas y Digestivas,Madrid,Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2016,2,25]]},"reference":[{"key":"lt24387-bib-0001-20240115","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1053\/j.gastro.2014.08.045","article-title":"Challenges to liver transplantation and strategies to improve outcomes","volume":"148","year":"2015","journal-title":"Gastroenterology"},{"key":"lt24387-bib-0002-20240115","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/nrgastro.2014.36","article-title":"Management of portal vein thrombosis in liver 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