{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T15:19:18Z","timestamp":1771082358462,"version":"3.50.1"},"reference-count":88,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:p>Liver transplant (LT) recipients are vulnerable to infections with multidrug\u2010resistant (MDR) pathogens. Risk factors for colonization and infection with resistant bacteria are ubiquitous and unavoidable in transplantation. During the past decade, progress in transplantation and infection prevention has contributed to the decreased incidence of infections with methicillin\u2010resistant <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic>. However, even in the face of potentially effective antibiotics, vancomycin\u2010resistant enterococci continue to plague LT. Gram\u2010negative bacilli prove to be more problematic and are responsible for high rates of both morbidity and mortality. Despite the licensure of novel antibiotics, there is no universal agent available to safely and effectively treat infections with MDR gram\u2010negative organisms. Currently, efforts dedicated toward prevention and treatment require involvement of multiple disciplines including transplant providers, specialists in infectious diseases and infection prevention, and researchers dedicated to the development of rapid diagnostics and safe and effective antibiotics with novel mechanisms of action. <jats:italic toggle=\"yes\">Liver Transplantation 22 1143\u20131153 2016 AASLD<\/jats:italic>\n                        <\/jats:p>","DOI":"10.1002\/lt.24486","type":"journal-article","created":{"date-parts":[[2016,5,26]],"date-time":"2016-05-26T23:58:24Z","timestamp":1464307104000},"page":"1143-1153","source":"Crossref","is-referenced-by-count":48,"title":["Multidrug\u2010resistant organisms in liver transplant: Mitigating risk and managing infections"],"prefix":"10.1097","volume":"22","author":[{"given":"Jonathan","family":"Hand","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Ochsner Clinic Foundation,The University of Queensland 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