{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T15:22:41Z","timestamp":1775575361416,"version":"3.50.1"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T00:00:00Z","timestamp":1486339200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2017,2,6]],"date-time":"2017-02-06T00:00:00Z","timestamp":1486339200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:p>Combined liver\u2010kidney transplantation (CLKT) is well established as a definitive therapy with the potential to provide complete recovery for certain liver\u2010kidney diseases, although the results might be contingent on the cause of transplantation. The purposes of the present study were to review the longterm outcome of renal allografts in CLKT patients from single living donors and to investigate the beneficial factors, compared with solitary renal transplantation. Thirteen patients underwent sequential liver transplantation (LT) and kidney transplantation (KT) from single living donors. The indications for KT were oxaluria (n\u2009=\u20097), autosomal recessive polycystic disease (n\u2009=\u20093), and others (n\u2009=\u20093). The same immunosuppressive regimen used after LT was also used after KT. KT was performed between 1.7 and 47.0 months after the LT. The overall patient survival rate was 92.3% at 10 years. In 12 of the 13 surviving patients, the renal allografts were found to be functioning in 11 patients after a mean follow\u2010up period of 103.6 months. The death\u2010censored renal allograft survival rate at 10 years was 100%, which was better than that of KT alone (84.9%) in Japan. Immunological protection conferred by the preceding liver allograft may have contributed to the longterm outcomes of the renal allografts. In addition, the donation of double organs from a single living and related donor may have a favorable impact on the graft survival rate. In the future, investigations of factors affecting the longterm outcome of renal allografts, including details of the involvement of de novo donor\u2010specific antibody, will be needed.<jats:italic toggle=\"yes\">Liver Transplantation 23 315\u2013323 2017 AASLD<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/lt.24676","type":"journal-article","created":{"date-parts":[[2016,11,15]],"date-time":"2016-11-15T13:25:48Z","timestamp":1479216348000},"page":"315-323","source":"Crossref","is-referenced-by-count":33,"title":["Longterm renal allograft survival after sequential liver\u2010kidney transplantation from a single living donor"],"prefix":"10.1097","volume":"23","author":[{"given":"Kumiko","family":"Kitajima","sequence":"first","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuyuki","family":"Miki","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotaro","family":"Kai","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihito","family":"Sannomiya","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Iwadoh","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toru","family":"Murakami","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Koyama","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ichiro","family":"Nakajima","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shohei","family":"Fuchinoue","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kidney Center,Tokyo Women's Medical University,Tokyo,Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2017,2,6]]},"reference":[{"key":"lt24676-bib-0001-20240115","first-page":"1077","article-title":"Combined liver and kidney transplantation","volume":"1","year":"1984","journal-title":"Lancet"},{"key":"lt24676-bib-0002-20240115","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/00000658-199112000-00007","article-title":"Causes of renal graft loss. 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