{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:15:33Z","timestamp":1791328533776,"version":"4.3.1"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:00:00Z","timestamp":1500422400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,7,19]],"date-time":"2017-07-19T00:00:00Z","timestamp":1500422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:p>Adequate portal vein (PV) flow in liver transplantation is essential for a good outcome, and it may be compromised in patients with portal vein thrombosis (PVT). This study evaluated the impact of intraoperatively measured PV flow after PV thrombendvenectomy on outcomes after deceased donor liver transplantation (DDLT). The study included 77 patients over a 16\u2010year period who underwent PV thrombendvenectomy with complete flow data. Patients were classified into 2 groups: high PV flow (&gt;1300\u2009mL\/minute; n\u2009=\u200955) and low PV flow (\u22641300\u2009mL\/minute; n\u2009=\u200922). Postoperative complications and graft survival were analyzed according to the PV flow. The 2 groups were similar in demographic characteristics. Low PV flow was associated with higher cumulative rates of biliary strictures (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.02) and lower 1\u2010, 2\u2010, and 5\u2010year graft survival (89%, 85%, and 68% versus 64%, 55%, and 38%, respectively; <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.002). There was no difference in the incidence of postoperative PVT between the groups (1.8% versus 9.1%; <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.19). No biliary leaks or hepatic artery thromboses were reported in either group. By multivariate analyses, age &gt;60 years (hazard ratio [HR], 3.04, 95% confidence interval [CI], 1.36\u20106.82; <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.007) and low portal flow (HR, 2.31; 95% CI, 1.15\u20104.65; <jats:italic toggle=\"yes\">P<\/jats:italic>\u2009=\u20090.02) were associated with worse survival. In conclusion, PV flow &lt;1300\u2009mL\/minute after PV thrombendvenectomy for PVT during DDLT was associated with higher rates of biliary strictures and worse graft survival. Consideration should be given to identifying reasons for low flow and performing maneuvers to increase PV flow when intraoperative PV flows are &lt;1300\u2009mL\/minute. <jats:italic toggle=\"yes\">Liver Transplantation 23 1032\u20131039 2017<\/jats:italic> AASLD.<\/jats:p>","DOI":"10.1002\/lt.24779","type":"journal-article","created":{"date-parts":[[2017,4,20]],"date-time":"2017-04-20T08:59:05Z","timestamp":1492678745000},"page":"1032-1039","source":"Crossref","is-referenced-by-count":18,"title":["Significance of measured intraoperative portal vein flows after thrombendvenectomy in deceased donor liver transplantations with portal vein thrombosis"],"prefix":"10.1097","volume":"23","author":[{"given":"Mark","family":"Draoua","sequence":"first","affiliation":[{"name":"Division of General Surgery"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Titze","sequence":"additional","affiliation":[{"name":"Department of Pediatrics,University of California,Irvine,CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amar","family":"Gupta","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoylan T.","family":"Fernandez","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Ramsay","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna","family":"Saracino","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"McKenna","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuliano","family":"Testa","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goran B.","family":"Klintmalm","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter T. W.","family":"Kim","sequence":"additional","affiliation":[{"name":"Simmons Transplant Institute,Baylor University Medical Center,Dallas,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2017,7,19]]},"reference":[{"key":"lt24779-bib-0001-20240122","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1002\/lt.22105","article-title":"Portal vein thrombosis and liver transplant survival benefit","volume":"16","year":"2010","journal-title":"Liver Transpl"},{"key":"lt24779-bib-0002-20240122","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.jhep.2004.01.001","article-title":"Risk factors and clinical presentation of portal vein thrombosis in patients with liver cirrhosis","volume":"40","year":"2004","journal-title":"J Hepatol"},{"key":"lt24779-bib-0003-20240122","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1006\/jsre.1996.0053","article-title":"A high incidence of native portal vein thrombosis in 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