{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T07:37:22Z","timestamp":1793345842916,"version":"4.5.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T00:00:00Z","timestamp":1513814400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,12,21]],"date-time":"2017-12-21T00:00:00Z","timestamp":1513814400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:p>Split\u2010liver transplantation has been perceived as an important strategy to increase the supply of liver grafts by creating 2 transplants from 1 allograft. The Eurotransplant Liver Allocation System (ELAS) envisages that the extended right lobes (ERLs) after splitting (usually in the pediatric center) are almost exclusively shipped to a second center. Whether the ELAS policy impacts the graft and patient survival of extended right lobe transplantation (ERLT) in comparison to whole liver transplantation (WLT) recipients remains unclear. Data on all liver transplantations performed between 2007 and 2013 were retrieved from the Eurotransplant Liver Follow\u2010up Registry (n = 5351). Of these, 5013 (269 ERL, 4744 whole liver) could be included. The impact of the transplant type on patient and graft survival was evaluated using univariate and multivariate proportional hazard models adjusting for demographics of donors and recipients. Cold ischemia times were significantly prolonged for ERLTs (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). Patient survival was not different between ERLT and WLT. In the univariate analysis, ERLT had a significantly higher risk for retransplantation (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.02). For WLT, the risk for death gradually and significantly increased with laboratory Model for End\u2010Stage Liver Disease (MELD) scores of &gt;20. For ERLT, this effect was seen already with laboratory MELD scores of &gt;14. These results mandate a discussion on how to refine the splitting policy to avoid excess retransplant rates in ERL recipients and to further improve transplant outcomes of these otherwise optimal donor organs. <jats:italic toggle=\"yes\">Liver Transplantation 24 26\u201334 2018<\/jats:italic> AASLD.<\/jats:p>","DOI":"10.1002\/lt.24980","type":"journal-article","created":{"date-parts":[[2017,11,16]],"date-time":"2017-11-16T16:05:45Z","timestamp":1510848345000},"page":"26-34","source":"Crossref","is-referenced-by-count":31,"title":["Higher retransplantation rate following extended right split\u2010liver transplantation: An analysis from the eurotransplant liver follow\u2010up registry"],"prefix":"10.1097","volume":"24","author":[{"given":"Joachim","family":"Andrassy","sequence":"first","affiliation":[{"name":"Department of Surgery,Ludwig\u2010Maximilian University,Munich,Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Wolf","sequence":"additional","affiliation":[{"name":"Department of Surgery,Ludwig\u2010Maximilian University,Munich,Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lauseker","sequence":"additional","affiliation":[{"name":"Institute for Biometrics and Epidemiology,Ludwig\u2010Maximilian University,Munich,Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Angele","sequence":"additional","affiliation":[{"name":"Department of Surgery,Ludwig\u2010Maximilian University,Munich,Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marieke D.","family":"van Rosmalen","sequence":"additional","affiliation":[{"name":"Eurotransplant International Foundation,Leiden,the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Undine","family":"Samuel","sequence":"additional","affiliation":[{"name":"Eurotransplant International Foundation,Leiden,the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Rogiers","sequence":"additional","affiliation":[{"name":"Eurotransplant International Foundation,Leiden,the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Werner","sequence":"additional","affiliation":[{"name":"Department of Surgery,Ludwig\u2010Maximilian University,Munich,Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Guba","sequence":"additional","affiliation":[{"name":"Department of Surgery,Ludwig\u2010Maximilian University,Munich,Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the Eurotransplant Liver Advisory 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