{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T11:57:09Z","timestamp":1792756629095,"version":"4.5.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,10,25]],"date-time":"2018-10-25T00:00:00Z","timestamp":1540425600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Split\u2010liver transplantation (SLT) should be cautiously considered because the right trisection (RTS) graft can be a marginal graft in adult recipients. Herein, we analyzed the outcomes of RTS\u2010SLT in Korea, where &gt;75% of adult liver transplantations are performed with living donor liver transplantation. Among 2462 patients who underwent deceased donor liver transplantations (DDLTs) from 2005 to 2014, we retrospectively reviewed 86 (3.5%) adult patients who received a RTS graft (RTS\u2010SLT group). The outcomes of the RTS\u2010SLT group were compared with those of 303 recipients of whole liver (WL; WL\u2010DDLT group). Recipient age, laboratory Model for End\u2010Stage\u2010Liver Disease (L\u2010MELD) score, ischemia time, and donor\u2010to\u2010recipient weight ratio (DRWR) were not different between the 2 groups (<jats:italic toggle=\"yes\">P <\/jats:italic>&gt; 0.05). However, malignancy was uncommon (4.7% versus 36.3%), and the donor was younger (25.2 versus 42.7 years) in the RST\u2010SLT group than in the WL\u2010DDLT group (<jats:italic toggle=\"yes\">P <\/jats:italic>&lt; 0.05). The technical complication rates and the 5\u2010year graft survival rates (89.0% versus 92.8%) were not different between the 2 groups (<jats:italic toggle=\"yes\">P <\/jats:italic>&gt; 0.05). The 5\u2010year overall survival (OS) rate (63.1%) and graft\u2010failure\u2010free survival rate (63.1%) of the RTS\u2010SLT group were worse than that of the WL\u2010DDLT group (79.3% and 79.3%; <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.05). The factors affecting graft survival rates were not definite. However, the factors affecting OS in the RTS\u2010SLT group were L\u2010MELD score &gt;30 and DRWR \u22641.0. In the subgroup analysis, OS was not different between the 2 groups if the DRWR was &gt;1.0, regardless of the L\u2010MELD score (<jats:italic toggle=\"yes\">P <\/jats:italic>&gt; 0.05). In conclusion, a sufficient volume of the graft estimated from DRWR\u2010matching could lead to better outcomes of adult SLTs with a RTS graft, even in patients with high L\u2010MELD scores.<\/jats:p>","DOI":"10.1002\/lt.25196","type":"journal-article","created":{"date-parts":[[2018,5,10]],"date-time":"2018-05-10T23:40:24Z","timestamp":1525995624000},"page":"1411-1424","source":"Crossref","is-referenced-by-count":33,"title":["Survival Outcomes in Split Compared With Whole Liver Transplantation"],"prefix":"10.1097","volume":"24","author":[{"given":"Kyung","family":"Chul Yoon","sequence":"first","affiliation":[{"name":"Department of Surgery,Seoul National University College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghee","family":"Song","sequence":"additional","affiliation":[{"name":"Transplantation Center,Seoul National University Hospital,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun\u2010Kyoung","family":"Jwa","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery,University of Ulsan College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery,Samsung Medical Center, Sungkyunkwan University School of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1903-8354","authenticated-orcid":false,"given":"Jong","family":"Man Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery,Samsung Medical Center, Sungkyunkwan University School of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ok\u2010kyoung","family":"Kim","sequence":"additional","affiliation":[{"name":"Transplantation Center,Seoul National University Hospital,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk","family":"Kyun Hong","sequence":"additional","affiliation":[{"name":"Department of Surgery,Seoul National University College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nam\u2010Joon","family":"Yi","sequence":"additional","affiliation":[{"name":"Department of Surgery,Seoul National University College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang\u2010Woong","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery,Seoul National University College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myoung","family":"Soo Kim","sequence":"additional","affiliation":[{"name":"Department of Surgery and The Research Institute for Transplantation,Yonsei University College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Hwang","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery,University of Ulsan College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung\u2010Suk","family":"Suh","sequence":"additional","affiliation":[{"name":"Department of Surgery,Seoul National University College of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk\u2010Koo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Surgery,Samsung Medical Center, Sungkyunkwan University School of Medicine,Seoul,South Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2018,10,25]]},"reference":[{"key":"lt25196-bib-0001-20240115","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jamcollsurg.2013.03.003","article-title":"Outcomes with split liver transplantation are equivalent to those with whole organ transplantation","volume":"217","year":"2013","journal-title":"J Am Coll Surg"},{"key":"lt25196-bib-0002-20240115","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1111\/j.1600-6143.2008.02211.x","article-title":"Factors affecting graft survival after adult\/child split\u2010liver transplantation: analysis of the UNOS\/OPTN data base","volume":"8","year":"2008","journal-title":"Am J Transplant"},{"key":"lt25196-bib-0003-20240115","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1002\/jhbp.292","article-title":"Uemoto S; for Japanese Liver Transplantation Society. Current status of deceased donor split liver transplantation in","volume":"22","year":"2015","journal-title":"Japan. J Hepatobiliary Pancreat Sci"},{"key":"lt25196-bib-0004-20240115","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1097\/01.sla.0000247254.76747.f3","article-title":"Long\u2010term outcome of split liver transplantation using right extended grafts in adulthood: a matched pair analysis","volume":"244","year":"2006","journal-title":"Ann Surg"},{"key":"lt25196-bib-0005-20240115","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1002\/lt.24135","article-title":"Right lobe split liver transplantation versus whole liver transplantation in adult recipients: a systematic review and meta\u2010analysis","volume":"21","year":"2015","journal-title":"Liver Transpl"},{"key":"lt25196-bib-0006-20240115","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/lt.24980","article-title":"for Eurotransplant Liver Advisory Committee. Higher retransplantation rate following extended right split\u2010liver transplantation: an analysis from the eurotransplant liver follow\u2010up registry","volume":"24","year":"2018","journal-title":"Liver Transpl"},{"key":"lt25196-bib-0007-20240115","doi-asserted-by":"crossref","first-page":"1384","DOI":"10.1002\/lt.24808","article-title":"A matched pair analysis of multicenter longterm follow\u2010up after split\u2010liver transplantation with extended right grafts","volume":"23","year":"2017","journal-title":"Liver Transpl"},{"key":"lt25196-bib-0008-20240115","doi-asserted-by":"crossref","first-page":"11003","DOI":"10.3748\/wjg.v21.i39.11003","article-title":"Current status and perspectives in split liver transplantation","volume":"21","year":"2015","journal-title":"World J Gastroenterol"},{"key":"lt25196-bib-0009-20240115","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/j.1600-6143.2006.01242.x","article-title":"Characteristics associated with liver graft failure: the concept of a donor risk index","volume":"6","year":"2006","journal-title":"Am J Transplant"},{"key":"lt25196-bib-0010-20240115","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1600-6143.2008.02491.x","article-title":"D\u2010MELD, a simple predictor of post liver transplant mortality for optimization of donor\/recipient matching","volume":"9","year":"2009","journal-title":"Am J Transplant"},{"key":"lt25196-bib-0011-20240115","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1111\/jgh.12930","article-title":"Dysfunction of liver regeneration in aged liver after partial hepatectomy","volume":"30","year":"2015","journal-title":"J Gastroenterol Hepatol"},{"key":"lt25196-bib-0012-20240115","doi-asserted-by":"crossref","first-page":"919","DOI":"10.3346\/jkms.2017.32.6.919","article-title":"Korean patients undergoing deceased donor liver transplantation for alcoholic liver disease have non\u2010inferior survival outcomes than for hepatitis B virus: a real\u2010world experience without minimum abstinence before transplantation","volume":"32","year":"2017","journal-title":"J Korean Med Sci"},{"key":"lt25196-bib-0013-20240115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4285\/jkstn.2011.25.1.1","article-title":"Optimal system for deceased organ donation and procurement in Korea","volume":"25","year":"2011","journal-title":"J Korean Soc Transplant"},{"key":"lt25196-bib-0015-20240115","doi-asserted-by":"crossref","first-page":"4052","DOI":"10.1016\/j.transproceed.2009.08.079","article-title":"Estimation of standard liver volume in Chinese adult living donors","volume":"41","year":"2009","journal-title":"Transplant Proc"},{"key":"lt25196-bib-0016-20240115","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1097\/01.sla.0000133083.54934.ae","article-title":"Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey","volume":"240","year":"2004","journal-title":"Ann Surg"},{"key":"lt25196-bib-0017-20240115","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1016\/S0041-1345(00)01606-7","article-title":"First successful in situ split\u2010liver transplantation in Korea","volume":"32","year":"2000","journal-title":"Transplant Proc"},{"key":"lt25196-bib-0018-20240115","doi-asserted-by":"crossref","first-page":"196","DOI":"10.4285\/jkstn.2012.26.3.196","article-title":"Status and current problems in the allocation system for pediatric liver transplantation in Korea","volume":"26","year":"2012","journal-title":"J Korean Soc Transplant"},{"key":"lt25196-bib-0019-20240115","article-title":"(D+10) MELD as a novel predictor of patient and graft survival after adult to adult living donor liver transplantation","volume":"31","year":"2017","journal-title":"Clin Transplant"},{"key":"lt25196-bib-0020-20240115","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1097\/SLA.0000000000001816","article-title":"Intention to split policy: a successful strategy in a combined pediatric and adult liver transplant center","volume":"265","year":"2017","journal-title":"Ann Surg"},{"key":"lt25196-bib-0021-20240115","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1097\/SLA.0000000000002419","article-title":"Comparison of postoperative outcomes between donation after circulatory death and donation after brain death liver transplantation using the comprehensive complication index","volume":"266","year":"2017","journal-title":"Ann Surg"},{"key":"lt25196-bib-0022-20240115","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.bpg.2017.03.002","article-title":"The use of old donors in liver transplantation","volume":"31","year":"2017","journal-title":"Best Pract Res Clin Gastroenterol"},{"key":"lt25196-bib-0023-20240115","doi-asserted-by":"crossref","first-page":"708","DOI":"10.12659\/AOT.900767","article-title":"L\u00e1zaro JL, Charco R. Does matching donor\u2010recipient age affect long\u2010term survival in liver transplantation?","volume":"21","year":"2016","journal-title":"Ann Transplant"},{"key":"lt25196-bib-0024-20240115","doi-asserted-by":"crossref","first-page":"3075","DOI":"10.1111\/ajt.13959","article-title":"Expanding the donor pool with normothermic ex vivo liver perfusion: the future is now","volume":"16","year":"2016","journal-title":"Am J Transplant"},{"key":"lt25196-bib-0025-20240115","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1002\/lt.24751","article-title":"Liver ex situ machine perfusion preservation: a review of the methodology and results of large animal studies and clinical trials","volume":"23","year":"2017","journal-title":"Liver Transpl"},{"key":"lt25196-bib-0026-20240115","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1136\/gut.2004.046524","article-title":"Wigmore SJ; for Edinburgh Liver Surgery and Transplantation Experimental Research Group (eLISTER). The value of residual liver volume as a predictor of hepatic dysfunction and infection after major liver resection","volume":"54","year":"2005","journal-title":"Gut"},{"key":"lt25196-bib-0027-20240115","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s40472-013-0006-1","article-title":"Early graft dysfunction in living donor liver transplantation and the small for size syndrome","volume":"1","year":"2014","journal-title":"Curr Transplant Rep"},{"key":"lt25196-bib-0028-20240115","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.jamcollsurg.2013.06.005","article-title":"Deceased\u2010donor split\u2010liver transplantation in adult recipients: is the learning curve over?","volume":"217","year":"2013","journal-title":"J Am Coll Surg"},{"key":"lt25196-bib-0029-20240115","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.trre.2016.11.002","article-title":"Graft inflow modulation in adult\u2010to\u2010adult living donor liver transplantation: a systematic review","volume":"31","year":"2017","journal-title":"Transplant Rev (Orlando)"},{"key":"lt25196-bib-0030-20240115","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/S1499-3872(12)60227-6","article-title":"Small\u2010for\u2010size syndrome in living donor liver transplantation","volume":"11","year":"2012","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"lt25196-bib-0031-20240115","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/hepr.13002","article-title":"Impact of preserved collateral veins on small\u2010for\u2010size grafts in living donor liver transplantation","volume":"48","year":"2018","journal-title":"Hepatol Res"},{"key":"lt25196-bib-0032-20240115","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1002\/lt.22440","article-title":"Left lobe adult\u2010to\u2010adult living donor liver transplantation: should portal inflow modulation be added?","volume":"18","year":"2012","journal-title":"Liver Transpl"},{"key":"lt25196-bib-0033-20240115","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1111\/hepr.12727","article-title":"A portal pressure cut\u2010off of 15 versus a cut\u2010off of 20 for prevention of small\u2010for\u2010size syndrome in liver transplantation: a comparative study","volume":"47","year":"2017","journal-title":"Hepatol Res"},{"key":"lt25196-bib-0034-20240115","doi-asserted-by":"crossref","first-page":"133","DOI":"10.14701\/kjhbps.2015.19.4.133","article-title":"Calculation of standard liver volume in Korean adults with analysis of confounding variables","volume":"19","year":"2015","journal-title":"Korean J Hepatobiliary Pancreat Surg"},{"key":"lt25196-bib-0035-20240115","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.transproceed.2014.12.037","article-title":"Outcome and technical aspects of liver retransplantation: analysis of 25\u2010year experience in a single major center","volume":"47","year":"2015","journal-title":"Transplant Proc"},{"key":"lt25196-bib-0036-20240115","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1002\/lt.24015","article-title":"Vasculobiliary complications following adult right lobe split liver transplantation from the perspective of reconstruction techniques","volume":"21","year":"2015","journal-title":"Liver Transpl"}],"container-title":["Liver Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Flt.25196","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/01445473-201810000-00015","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,15]],"date-time":"2024-01-15T01:21:52Z","timestamp":1705281712000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01445473-201810000-00015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":35,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1002\/lt.25196","relation":{},"ISSN":["1527-6465","1527-6473"],"issn-type":[{"value":"1527-6465","type":"print"},{"value":"1527-6473","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}