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Cystic fibrosis with advanced liver disease and portal hypertension (CFLD) represents the most significant risk to patient mortality, second only to pulmonary or lung transplant complications in patients with CF. Currently, there is no medical therapy to treat or reverse CFLD. Liver transplantation (LT) in patients with CFLD with portal hypertension confers a significant survival advantage over those who do not receive LT, although the timing in which to optimize this benefit is unclear. Despite the value and efficacy of LT in selected patients with CFLD, established clinical criteria outlining indications and timing for LT as well as disease\u2010specific transplant considerations are notably absent. The goal of this comprehensive and multidisciplinary report is to present recommendations on the unique CF\u2010specific pre\u2010 and post\u2010LT management issues clinicians should consider and will face.<\/jats:p>","DOI":"10.1002\/lt.25421","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T06:34:21Z","timestamp":1548830061000},"page":"640-657","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["A Multidisciplinary Approach to Pretransplant and Posttransplant Management of Cystic Fibrosis\u2013Associated Liver Disease"],"prefix":"10.1097","volume":"25","author":[{"given":"A. 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