{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T00:31:27Z","timestamp":1790987487164,"version":"4.1.0"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T00:00:00Z","timestamp":1553817600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,3,29]],"date-time":"2019-03-29T00:00:00Z","timestamp":1553817600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["P30 DK026743"],"award-info":[{"award-number":["P30 DK026743"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","award":["T32 DK060414"],"award-info":[{"award-number":["T32 DK060414"]}],"id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2019,5]]},"abstract":"<jats:p>Alcohol\u2010associated liver disease (ALD) can be coded in United Network for Organ Sharing (UNOS) as either alcoholic cirrhosis or alcoholic hepatitis (AH), without having specific criteria to assign either diagnosis. In this multicenter American Consortium of Early Liver Transplantation for Alcoholic Hepatitis (ACCELERATE\u2010AH) study, we sought to assess the concordance of the clinician diagnosis of AH at liver transplantation (LT) listing versus UNOS data entry of AH as listing diagnosis. In a prior study, consecutive early LT recipients transplanted for AH between 2012 and 2017 were identified by chart review at 10 ACCELERATE\u2010AH sites. In this current study, these same LT recipients were identified in the UNOS database. The primary UNOS diagnostic code was evaluated for concordance with the chart\u2010review assignment of AH. In cases where the primary listing diagnosis in UNOS was not AH, we determined the reason for alternate classification. Among 124 ACCELERATE\u2010AH LT recipients with a chart\u2010review diagnosis of AH, only 43\/124 (35%) had AH as listing diagnosis in UNOS; 80 (64%) were listed as alcoholic cirrhosis, and 1 (1%) as fulminant hepatic necrosis. Of the 81 patients missing AH as a UNOS listing diagnosis code, the reasons for alternate classification were 44 (54%) due to a lack of awareness of a separate diagnosis code for AH; 13 (16%) due to concomitant clinical diagnosis of AH and alcoholic cirrhosis in the chart; 12 (15%) due to clinical uncertainty regarding the diagnosis of AH versus acute decompensated alcoholic cirrhosis; and 12 (15%) due to a data entry error. In conclusion, in a large cohort of LT recipients with AH, only 35% were documented as such in UNOS. Increased education and awareness for those performing UNOS data entry, the establishment of specific criteria to define AH in the UNOS database, and the ability to document dates of alcohol use would allow future research on ALD to be more informative.<\/jats:p>","DOI":"10.1002\/lt.25448","type":"journal-article","created":{"date-parts":[[2019,3,18]],"date-time":"2019-03-18T19:14:22Z","timestamp":1552936462000},"page":"706-711","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":35,"title":["Underestimation of Liver Transplantation for Alcoholic Hepatitis in the National Transplant Database"],"prefix":"10.1097","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2108-1287","authenticated-orcid":false,"given":"Brian P.","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Gastroenterology,University of California, San Francisco,San Francisco,CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0009-8418","authenticated-orcid":false,"given":"Gene Y.","family":"Im","sequence":"additional","affiliation":[{"name":"Department of Liver Diseases,Icahn School of Medicine at Mount Sinai,New York City,NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Rice","sequence":"additional","affiliation":[{"name":"Department of Medicine,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ethan","family":"Weinberg","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Perelman School of Medicine at the University of Pennsylvania,Philadelphia,PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Hsu","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Georgetown University School of Medicine,Washington,DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oren K.","family":"Fix","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Swedish Medical Center,Seattle,WA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6113-4972","authenticated-orcid":false,"given":"George","family":"Therapondos","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Ochsner Medical Center,Jefferson,LA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyosun","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Keck School of Medicine of University of Southern California,Los Angeles,CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Victor","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Houston Methodist Hospital,Houston,TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Eswaran","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Rush Medical College,Chicago,IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haripriya","family":"Maddur","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Northwestern University Feinberg School of Medicine,Chicago,IL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norah A.","family":"Terrault","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology,Keck School of Medicine of University of Southern California,Los Angeles,CA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,3,29]]},"reference":[{"key":"lt25448-bib-0001-20240115","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1016\/j.cgh.2017.11.045","article-title":"Alcoholic liver disease replaces hepatitis C virus infection as the leading indication for liver transplantation in the United States","volume":"16","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"lt25448-bib-0002-20240115","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1053\/j.gastro.2018.04.009","article-title":"Outcomes of early liver transplantation for patients with severe alcoholic hepatitis","volume":"155","year":"2018","journal-title":"Gastroenterology"},{"key":"lt25448-bib-0003-20240115","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1056\/NEJMoa1105703","article-title":"Early liver transplantation for severe alcoholic hepatitis","volume":"365","year":"2011","journal-title":"N Engl J Med"},{"key":"lt25448-bib-0004-20240115","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1053\/j.gastro.2016.02.042","article-title":"Standard definitions and common data elements for clinical trials in patients with alcoholic hepatitis: recommendation from the NIAAA 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