{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:26:40Z","timestamp":1787498800324,"version":"build-2736575974"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","license":[{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T00:00:00Z","timestamp":1568937600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:p>\n                    Liver transplantation (LT) for small infants remains challenging because of the demands related to graft selection, surgical technique, and perioperative management. The aim of this study was to evaluate the short\u2010term and longterm outcomes of LT regarding vascular\/biliary complications, renal function, growth, and patient\/graft survival in infants \u22643\u00a0months compared with those of an age between &gt;3 and 6\u00a0months at a single transplant center. A total of 64 infants \u22646\u00a0months underwent LT and were divided into 2 groups according to age at LT: those of age \u22643\u00a0months (range, 6\u2010118\u00a0days; XS group, n\u00a0=\u00a037) and those of age &gt;3 to \u22646\u00a0months (range, 124\u2010179\u00a0days; S group, n\u00a0=\u00a027) between 1989 and 2014. Acute liver failure was the main indication for LT in the XS group (n\u00a0=\u00a031, 84%) versus S (n\u00a0=\u00a07, 26%). The overall incidence of hepatic artery thrombosis and portal vein thrombosis\/stricture were 5.4% and 10.8% in the XS group and 7.4% and 11.1% in the S group, respectively (not significant). The overall incidence of biliary stricture and leakage were 5.4% and 2.7% in the XS group and 3.7% and 3.7% in the S group, respectively (not significant). There was no significant difference between the 2 groups in terms of renal function. No significant difference was found between the 2 groups for each year after LT in terms of height and weight\n                    <jats:italic toggle=\"yes\">z<\/jats:italic>\n                    score. The 1\u2010, 5\u2010, and 10\u2010year patient survival rates were 70.3%, 70.3%, and 70.3% in the XS group compared with 92.6%, 88.9%, and 88.9% in the S group, respectively (not significant). In conclusion, LT for smaller infants has acceptable outcomes despite the challenges of surgical technique, including vascular reconstruction and graft preparation, and perioperative management.\n                  <\/jats:p>","DOI":"10.1002\/lt.25619","type":"journal-article","created":{"date-parts":[[2019,8,5]],"date-time":"2019-08-05T01:29:27Z","timestamp":1564968567000},"page":"1561-1570","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Outcomes of Liver Transplantation in Small Infants"],"prefix":"10.1097","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4734-5084","authenticated-orcid":false,"given":"Hidekazu","family":"Yamamoto","sequence":"first","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirin E.","family":"Khorsandi","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Cortes\u2010Cerisuelo","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoichi","family":"Kawano","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Dhawan","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"McCall","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hector","family":"Vilca\u2010Melendez","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Rela","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nigel","family":"Heaton","sequence":"additional","affiliation":[{"name":"Liver Transplantation, Institute of Liver Studies,King\u2019s College Hospital,London,United 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