{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:53:59Z","timestamp":1787846039766,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T00:00:00Z","timestamp":1637798400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,11,25]],"date-time":"2021-11-25T00:00:00Z","timestamp":1637798400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Liver Transpl"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:p>\n                    The Stanford Integrated Psychosocial Assessment for Transplant (SIPAT) is a validated interview tool to assess psychosocial well\u2010being in candidates for solid organ transplants, with higher scores indicating greater vulnerability. We hypothesized that patients with alcohol\u2010related liver disease (ALD) undergoing liver transplantation (LT) evaluation would have higher SIPAT scores than candidates with non\u2010ALD, but that only patients with ALD who have low scores would be selected. We analyzed retrospectively consecutive adults undergoing LT evaluation from June 2018 to December 2019. Comparisons between patients with ALD and patients with non\u2010ALD were made using the nonparametric Wilcoxon rank sum test plus a multivariate analysis to determine independent predictors for approval. In the study cohort of 358 patients, there were 199 (56%) patients with ALD with a mean age of 55\u00a0years, and 133 (67%) were men. There were 159 (44%) patients with non\u2010ALD with a mean age of 57\u00a0years, and 95 (60%) were men. Mean Model for End\u2010Stage Liver Disease\u2013sodium scores were similar for selected versus not selected patients with ALD (25 versus 25.6) and selected versus not selected patients with non\u2010ALD (18.3 versus 17.4), although the ALD group had substantially higher Model for End\u2010Stage Liver Disease scores. Patients with ALD had higher mean SIPAT composite and individual domain scores compared with their non\u2010ALD counterparts. SIPAT scores were not affected by age or sex. Proportionately more candidates with non\u2010ALD were selected compared to candidates with ALD (68% versus 42%;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u00a0&lt;\u00a00.001; odds ratio for approval of non\u2010ALD versus ALD, 2.9; 95% confidence interval, 1.8\u20104.7;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u00a0&lt;\u00a00.001). Composite SIPAT scores were lower in the selected versus nonselected in both ALD and non\u2010ALD groups, although the SIPAT scores were significantly higher in selected patients with ALD (median, 39) than selected patients with non\u2010ALD (median, 23;\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u00a0=\u00a00.001). Psychosocial assessment has a greater influence than acuity of liver failure on the selection of patients with ALD for LT listing, whereas psychosocial assessment has a minor influence on the selection of non\u2010ALD candidates.\n                  <\/jats:p>","DOI":"10.1002\/lt.26324","type":"journal-article","created":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T08:57:32Z","timestamp":1633078652000},"page":"936-944","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":35,"title":["Psychosocial Assessment Rather Than Severity of Liver Failure Dominates Selection for Liver Transplantation in Patients With Alcohol\u2010Related Liver Disease"],"prefix":"10.1097","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8449-2166","authenticated-orcid":false,"given":"Kimberly E.","family":"Daniel","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsay A.","family":"Matthews","sequence":"additional","affiliation":[{"name":"Department of Medicine,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimrod","family":"Deiss\u2010Yehiely","sequence":"additional","affiliation":[{"name":"Department of Medicine,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Myers","sequence":"additional","affiliation":[{"name":"Division of Transplantation,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maureen","family":"Garvey","sequence":"additional","affiliation":[{"name":"Division of Transplantation,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John P.","family":"Rice","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jens","family":"Eickhoff","sequence":"additional","affiliation":[{"name":"Department of Biostatistics and Medical Informatics,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael R.","family":"Lucey","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology,University of Wisconsin School of Medicine and Public Health,Madison,WI"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,11,25]]},"reference":[{"key":"lt26324-bib-0001-20250824","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1001\/jamapsychiatry.2017.2161","article-title":"Prevalence of 12\u2010month alcohol use, high\u2010risk drinking, and DSM\u2010IV alcohol use disorder in the United States, 2001\u20102002 to 2012\u20102013: results from the National Epidemiologic Survey on Alcohol and Related Conditions","volume":"74","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"lt26324-bib-0002-20250824","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/hep.30866","article-title":"Diagnosis and treatment of alcohol\u2010associated liver diseases: 2019 practice guidance from the American Association for the Study of Liver Diseases","volume":"71","year":"2020","journal-title":"Hepatology"},{"key":"lt26324-bib-0003-20250824","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1016\/j.cgh.2017.11.045","article-title":"Alcoholic liver disease replaces hepatitis C virus infection as the leading indication for liver transplantation in the United States","volume":"16","year":"2018","journal-title":"Clin Gastroenterol Hepatol"},{"key":"lt26324-bib-0004-20250824","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jhep.2015.10.006","article-title":"EASL clinical practice guidelines: liver transplantation","volume":"64","year":"2016","journal-title":"J Hepatol"},{"key":"lt26324-bib-0005-20250824","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1053\/j.gastro.2016.02.042","article-title":"Standard definitions and common data elements for clinical trials in patients with alcoholic hepatitis: recommendation from the NIAAA Alcoholic Hepatitis Consortia","volume":"150","year":"2016","journal-title":"Gastroenterology"},{"key":"lt26324-bib-0007-20250824","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1002\/hep.26972","article-title":"Evaluation for liver transplantation in adults: 2013 practice guideline by the American Association for the Study of Liver Diseases and the American Society of Transplantation","volume":"59","year":"2014","journal-title":"Hepatology"},{"key":"lt26324-bib-0009-20250824","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1002\/lt.500030613","article-title":"Minimal criteria for placement of adults on the liver transplant waiting list: a report of a national conference organized by the American Society of Transplant Physicians and the American Association for the Study of Liver Diseases","volume":"3","year":"1997","journal-title":"Liver Transpl 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Med"},{"key":"lt26324-bib-0013-20250824","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1056\/NEJM197804202981605","article-title":"Taking care of the hateful patient","volume":"298","year":"1978","journal-title":"N Engl J Med"},{"key":"lt26324-bib-0014-20250824","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1136\/bmj.317.7152.172","article-title":"Assessing priorities for allocation of donor liver grafts: survey of public and clinicians","volume":"317","year":"1998","journal-title":"BMJ"},{"key":"lt26324-bib-0015-20250824","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1002\/lt.25975","article-title":"The Stanford Integrated Psychosocial Assessment for transplant is associated with outcomes before and after liver transplantation","volume":"27","year":"2021","journal-title":"Liver Transpl"},{"key":"lt26324-bib-0016-20250824","doi-asserted-by":"crossref","first-page":"2089","DOI":"10.1007\/s10620-019-05937-4","article-title":"Prior relapse, ongoing 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fibrosis","volume":"19","year":"2013","journal-title":"Liver Transpl"}],"container-title":["Liver 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