{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T22:11:53Z","timestamp":1784326313765,"version":"3.55.0"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005006","name":"Asan Institute for Life Sciences, Asan Medical Center","doi-asserted-by":"publisher","award":["2020IL0034\u20101"],"award-info":[{"award-number":["2020IL0034\u20101"]}],"id":[{"id":"10.13039\/501100005006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005006","name":"Asan Institute for Life Sciences, Asan Medical Center","doi-asserted-by":"publisher","award":["2021IT0005\u20101"],"award-info":[{"award-number":["2021IT0005\u20101"]}],"id":[{"id":"10.13039\/501100005006","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Extracorporeal membrane oxygenation (ECMO) has been used sporadically in adult orthotopic liver transplantation (OLT) recipients for the treatment of acute cardiopulmonary failure. This retrospective study aimed to identify OLT patients who would benefit from ECMO support. We reviewed 109 OLT patients who received ECMO support for more than 24\u2009h from January 2007 to December 2020. Among the enrolled patients, 15 (13.8%) experienced 18 ECMO\u2010related complications and 12 (11.0%) experienced ECMO reapplication after weaning during the same hospitalization period. The successful weaning rates were 50.98% in patients who received ECMO support during the peritransplantation period (0\u201330 days from transplantation) and 51.72% in patients who received ECMO support in the post\u2010OLT period (more than 30 days after OLT); 24 (47.1%) and 23 (39.7%) patients survived until hospital discharge, respectively. The 109 enrolled OLT recipients who received ECMO support during the perioperative period had a 1\u2010year survival rate of 42.6%. Multivariate analyses identified the following as significant and independent risk factors for in\u2010hospital mortality: ECMO treatment prior to 2011 (<jats:italic toggle=\"yes\">p<\/jats:italic> = 0.04), septic shock as the indication for ECMO treatment (<jats:italic toggle=\"yes\">p<\/jats:italic> = 0.001), and a total bilirubin level of \u22655.0 mg\/dl (<jats:italic toggle=\"yes\">p<\/jats:italic> = 0.02). The outcomes of adult OLT recipients with ECMO treatment were acceptable in terms of weaning success and survival until hospital discharge. This study confirmed that ECMO treatment for OLT recipients with septic shock and elevated bilirubin levels might be associated with a higher in\u2010hospital mortality and demonstrated the importance of a multidisciplinary ECMO team approach.<\/jats:p>","DOI":"10.1002\/lt.26567","type":"journal-article","created":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T15:59:45Z","timestamp":1661702385000},"page":"67-79","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Role of extracorporeal membrane oxygenation as a salvage therapy for liver transplantation recipients in a high\u2010volume transplant center"],"prefix":"10.1097","volume":"29","author":[{"given":"Young\u2010In","family":"Yoon","sequence":"first","affiliation":[{"name":"Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung\u2010Hyeon","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung\u2010Gyu","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pil\u2010Je","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyu\u2010Sam","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su\u2010Min","family":"Ha","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ha\u2010Yeon","family":"Do","sequence":"additional","affiliation":[{"name":"Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk\u2010Kyung","family":"Hong","sequence":"additional","affiliation":[{"name":"Division of Acute Care Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin\u2010Won","family":"Huh","sequence":"additional","affiliation":[{"name":"Department of Pulmonary and Critical Care Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"key":"R1-20250501","first-page":"31","article-title":"Cardiovascular dysfunction in patients with liver cirrhosis","volume":"28","year":"2015","journal-title":"Ann 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The Respiratory Extracorporeal Membrane Oxygenation Survival Prediction (RESP) score","volume":"189","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"key":"R10-20250501","article-title":"Contraindications to the initiation of veno\u2010venous ECMO for severe acute respiratory failure in adults: a systematic review and practical approach based on the current literature","volume":"11","year":"2021","journal-title":"Membranes (Basel)"},{"key":"R11-20250501","article-title":"Prediction of mortality in adult patients with severe acute lung failure receiving veno\u2010venous extracorporeal membrane oxygenation: a prospective observational study","volume":"18","year":"2014","journal-title":"Crit Care"},{"key":"R12-20250501","first-page":"788","article-title":"Clinical outcomes of immunocompromised patients on extracorporeal membrane oxygenation support for severe acute respiratory failure","volume":"57","year":"2020","journal-title":"Eur J Cardiothorac 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