{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T16:21:39Z","timestamp":1780071699249,"version":"3.54.0"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,2,10]],"date-time":"2014-02-10T00:00:00Z","timestamp":1391990400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":568,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["wiley.com"],"crossmark-restriction":true},"short-container-title":["Macromolecular Bioscience"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec><jats:label\/><jats:p>Alginate hydrogels functionalized with <jats:sc>D\u2010,<\/jats:sc> or<jats:sc> L<\/jats:sc>\u2010penicillamine (<jats:sc>D\u2010, L<\/jats:sc>\u2010PEN\u2010Alg) are used as new 3D scaffolds for cell adhesion studies. The cells recognize and show different adhesion properties in the respective 3D hydrogel scaffolds. C\u20106\u2010glioma and endothelial cells show higher affinity to the <jats:sc>D<\/jats:sc>\u2010PEN than to the <jats:sc>L<\/jats:sc>\u2010PEN functionalized 3D alginate hydrogel scaffold. The cultivated cells are harvested from the hydrogel and are reused, for example, for cell growth experiments on 2D surfaces to prove their viability as well.<jats:inline-graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"graphic\/mabi201300485-gra-0001.png\" xlink:title=\"mabi201300485-gra-0001\"\/><\/jats:p><\/jats:sec>","DOI":"10.1002\/mabi.201300485","type":"journal-article","created":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T20:36:57Z","timestamp":1392151017000},"page":"793-798","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Cell Adhesion Behavior in 3D Hydrogel Scaffolds Functionalized with <scp>D<\/scp>\u2010 or <scp>L<\/scp>\u2010Aminoacids"],"prefix":"10.1002","volume":"14","author":[{"given":"Kathrin","family":"Benson","sequence":"first","affiliation":[{"name":"Institut f\u00fcr Biochemie Westf\u00e4lische Wilhelms\u2010Universit\u00e4t M\u00fcnster Wilhelm\u2010Klemm\u2010Str. 2 D\u201048149 M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans\u2010Joachim","family":"Galla","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Biochemie Westf\u00e4lische Wilhelms\u2010Universit\u00e4t M\u00fcnster Wilhelm\u2010Klemm\u2010Str. 2 D\u201048149 M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nermin Seda","family":"Kehr","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Biochemie Westf\u00e4lische Wilhelms\u2010Universit\u00e4t M\u00fcnster Wilhelm\u2010Klemm\u2010Str. 2 D\u201048149 M\u00fcnster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,2,10]]},"reference":[{"key":"e_1_2_5_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2008.01.012"},{"key":"e_1_2_5_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/pi.2253"},{"key":"e_1_2_5_1_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200502004"},{"key":"e_1_2_5_1_4","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200401239"},{"key":"e_1_2_5_1_5","doi-asserted-by":"publisher","DOI":"10.1021\/cm048093x"},{"key":"e_1_2_5_1_6","doi-asserted-by":"publisher","DOI":"10.1016\/S0939-6411(00)00090-4"},{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican0509-64"},{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.8493529"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1039\/c0cs00124d"},{"key":"e_1_2_5_3_2","first-page":"1","volume":"126","author":"Hayes J. S.","year":"2011","journal-title":"Adv. Biochem. Eng. Biotechnol."},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/la701415z"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/b802235f"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/bm700606z"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/bip.20989"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2008.02.003"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201206951"},{"key":"e_1_2_5_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201104437"},{"key":"e_1_2_5_7_3","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201000205"},{"key":"e_1_2_5_7_4","doi-asserted-by":"publisher","DOI":"10.1007\/12_071"},{"key":"e_1_2_5_7_5","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(99)00158-1"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201109144"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/la204143g"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1039\/C1CS15209B"},{"key":"e_1_2_5_9_3","doi-asserted-by":"publisher","DOI":"10.1039\/c0sm00151a"},{"key":"e_1_2_5_9_4","doi-asserted-by":"publisher","DOI":"10.1021\/ja0686155"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8128221"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2011.10.016"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201101032"},{"key":"e_1_2_5_11_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200806295"},{"key":"e_1_2_5_11_4","doi-asserted-by":"publisher","DOI":"10.1021\/ja8044184"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/bm301598g"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2510010205"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.200600069"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1021\/bm070014y"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-2697(02)00506-7"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1385-299X(00)00020-9"}],"container-title":["Macromolecular Bioscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmabi.201300485","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mabi.201300485","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T11:32:06Z","timestamp":1696505526000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mabi.201300485"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,10]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,6]]}},"alternative-id":["10.1002\/mabi.201300485"],"URL":"https:\/\/doi.org\/10.1002\/mabi.201300485","archive":["Portico"],"relation":{},"ISSN":["1616-5187","1616-5195"],"issn-type":[{"value":"1616-5187","type":"print"},{"value":"1616-5195","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,2,10]]},"assertion":[{"value":"2014-02-10","name":"published_online","label":"Published Online","group":{"name":"publication_history","label":"Publication History"}}]}}