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Compared with prefabricated hydrogels, injectable hydrogels can be implanted more accurately into deeply enclosed sites and repair irregularly shaped lesions, showing great applicable potential. Here, the current fabrication considerations of injectable dual crosslinking hydrogels are reviewed. Besides, the progress of the hydrogels used in corresponding applications and emerging challenges are discussed, with detailed emphasis in the fields of bone and cartilage regeneration, wound dressings, sensors and other less mentioned applications for their more hopeful employments in clinic. 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