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Poly(ether\u2010ether\u2010ketone) (PEEK) is a promising material for orthopedic applications. To further understand and improve the interfacial tribological properties between PEEK implant and host bone tissue, a PEEK\u2010cortical bone tribo\u2010pair is designed and fabricated. The frictional and wear performance of such tribo\u2010pair is investigated under different lubricants, i.e., simulated body fluid (SBF), calf serum (CS), hyaluronic acid (HA), and mucin (MUC). The results suggest that MUC solution can be utilized as an artificial natural synovial fluid to improve the tribological properties of PEEK\u2010based implants.<\/jats:p>","DOI":"10.1002\/mabi.202200548","type":"journal-article","created":{"date-parts":[[2023,3,19]],"date-time":"2023-03-19T03:33:55Z","timestamp":1679196835000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Study on the Friction and Wear Properties of PEEK against Cortical Bone Tissue Under Different Lubricating Conditions"],"prefix":"10.1002","volume":"23","author":[{"given":"Xiao","family":"Zhang","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering Shenzhen Campus of Sun Yat\u2010sen University  Shenzhen 518107 P. R. 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