{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:09:59Z","timestamp":1790294999628,"version":"4.1.0"},"reference-count":60,"publisher":"Wiley","license":[{"start":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T00:00:00Z","timestamp":1716422400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Macromolecular Bioscience"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Controlling infections while reducing the use of antibiotics is what doctors as well as researchers are looking for. As innovative smart materials, photothermal materials can achieve localized heating under light excitation for broad\u2010spectrum bacterial inhibition. A polydopamine\/chitosan\/\u03b2\u2010glycerophosphate temperature\u2010sensitive hydrogel with excellent antibacterial ability is synthesized here. Initially, the hydrogel has good biocompatibility. In vitro experiments reveal its noncytotoxic property when cocultured with gingival fibroblasts and nonhemolytic capability. Concurrently, the in vivo biocompatibility is confirmed through liver and kidney blood markers and staining of key organs. Crucially, the hydrogel has excellent photothermal conversion performance, which can realize the photothermal conversion of hydrogel up to 3\u00a0mm thickness. When excited by near\u2010infrared light, localized heating is attainable, resulting in clear inhibition impacts on both\n                    <jats:italic>Staphylococcus aureus<\/jats:italic>\n                    and\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    , with the inhibition rates of 91.22% and 96.69%, respectively. During studies on mice's infected wounds, it is observed that the hydrogel can decrease\n                    <jats:italic>S. aureus<\/jats:italic>\n                    \u2019 presence in the affected area when exposed to near\u2010infrared light, and also lessen initial inflammation and apoptosis, hastening tissue healing. These findings provide valuable insights into the design of antibiotic\u2010free novel biomaterials with good potential for clinical applications.\n                  <\/jats:p>","DOI":"10.1002\/mabi.202400080","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T08:03:49Z","timestamp":1715846629000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Injectable Photothermal PDA\/Chitosan\/\u03b2\u2010Glycerophosphate Thermosensitive Hydrogels for Antibacterial and Wound Healing Promotion"],"prefix":"10.1002","author":[{"given":"Dingkun","family":"Liu","sequence":"first","affiliation":[{"name":"Fujian Key Laboratory of Oral Diseases and Fujian Provincial Engineering Research Center of Oral Biomaterial and Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology Fujian Medical University  88 Jiaotong Road Fuzhou Fujian 350004 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Diseases and Fujian Provincial Engineering Research Center of Oral Biomaterial and Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology Fujian Medical University  88 Jiaotong Road Fuzhou Fujian 350004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liujun","family":"Lin","sequence":"additional","affiliation":[{"name":"Fujian Key Laboratory of Oral Diseases and Fujian Provincial Engineering Research Center of Oral Biomaterial and Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology Fujian Medical University  88 Jiaotong Road Fuzhou Fujian 350004 China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Wei","sequence":"additional","affiliation":[{"name":"Fujian Key Laboratory of Oral Diseases and Fujian Provincial Engineering Research Center of Oral Biomaterial and Stomatological Key Lab of Fujian College and University, School and Hospital of Stomatology 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