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Herein, polyethylene glycol (PEG)\u2010based antibacterial hydrogel sponge dressings are prepared by a rapid and facile gas foaming method based on an acid chloride\/alcohol reaction where tannic acid (TA) is included as a reactant to impart antibacterial efficacy as well as to enhance the mechanical properties of the samples. The results reveal that the TA\u2010integrated sponges possess excellent antibacterial properties against both <jats:italic>Escherichia coli<\/jats:italic> and <jats:italic>Staphylococcus aureus<\/jats:italic> with approximately 6\u20138 log reduction in the microbial colony count after 6\u00a0h, indicating their high potential for management of infection\u2010prone wounds. Compared to the control sample, TA incorporation increases the elastic modulus by twofold. As the samples also exhibit biocompatibility, antioxidant activity, and wound healing capacity, the novel TA\u2010incorporated hydrogels can be an alternative to traditional wound dressings for wounds with low\u2010to\u2010moderate exudate.<\/jats:p>","DOI":"10.1002\/mabi.202400101","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T18:09:00Z","timestamp":1715796540000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Tannic Acid Incorporated Antibacterial Polyethylene Glycol Based Hydrogel Sponges for Management of Wound Infections"],"prefix":"10.1002","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9223-659X","authenticated-orcid":false,"given":"Basak","family":"Akin","sequence":"first","affiliation":[{"name":"Yildiz Technical University Department of Bioengineering  Istanbul 34220 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