{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:23:29Z","timestamp":1788931409003,"version":"build-2803163510"},"reference-count":77,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T00:00:00Z","timestamp":1759190400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Macromolecular Bioscience"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Stimuli\u2010responsive polymeric fibers have emerged as an indispensable material for numerous biomedical applications. Strategies to conjugate functional molecules with high specificity onto these nanofibers are vital to tailor these materials for specific applications. When the functionalization is reversible, these materials can serve as a \u2018catch and release\u2019 platform, which widens their applicability. Herein, polymeric fibers with an average diameter of about 237 \u00b1 44\u00a0nm, amenable to reversible conjugation, are fabricated using electrospinning. The thiol\u2010disulfide exchange reaction is employed to functionalize the electrospun fibers with thiol\u2010containing functional molecules ranging from fluorescent dyes to bioactive ligands for protein immobilization. It is demonstrated that the linked (bio)molecules can be efficiently released in the presence of a thiol\u2010containing reducing agent. Specifically, pyridyl disulfide (PDS)\u2010containing copolymers are synthesized using a thiol\u2010reactive PDS\u2010based monomer, methyl methacrylate, and poly(ethylene glycol) methacrylate, where the monomers enable thiol\u2010based specific functionalization, stable fiber formation, and anti\u2010biofouling characteristics, respectively. After demonstrating efficient functionalization and release using fluorescent dyes and bioactive ligands, these fibers are conjugated with a thiol\u2010containing cationic antibacterial peptide. It is demonstrated that the released peptide preserves its antibacterial activity against planktonic bacteria as well as biofilms. One can envision that the facile fabrication, efficient functionalization, and on\u2010demand release attribute of these reversibly functionalizable polymeric fibers disclosed here would be attractive platforms for a wide range of biomedical applications.<\/jats:p>","DOI":"10.1002\/mabi.202500346","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T07:26:28Z","timestamp":1759303588000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["\u2018Catch and Release\u2019 Polymeric Fibers: Versatile Interfaces for Engineering Reversible Platforms for Biomolecular Immobilization and Antibacterial Coatings"],"prefix":"10.1002","volume":"26","author":[{"given":"Meltem","family":"Alkis","sequence":"first","affiliation":[{"name":"Department of Chemistry Bogazici University  Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre","family":"Barras","sequence":"additional","affiliation":[{"name":"Univ. Lille CNRS Univ. Polytechnique Hauts\u2010De\u2010France  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabah","family":"Boukherroub","sequence":"additional","affiliation":[{"name":"Univ. Lille CNRS Univ. Polytechnique Hauts\u2010De\u2010France  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabine","family":"Szunerits","sequence":"additional","affiliation":[{"name":"Univ. Lille CNRS Univ. Polytechnique Hauts\u2010De\u2010France  Lille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5122-8329","authenticated-orcid":false,"given":"Amitav","family":"Sanyal","sequence":"additional","affiliation":[{"name":"Department of Chemistry Bogazici University  Istanbul T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200803092"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/marc.202400903"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.07.038"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00094"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202301563"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2017.10.003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201702646"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/pat.1813"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201800256"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1385\/ABAB:125:3:147"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2020.105224"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201400166"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/ten.2005.11.101"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-3538(03)00178-7"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsapm.0c00665"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1088\/0957-4484\/17\/14\/R01"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200604646"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2010.01.004"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00593"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/app.21481"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/am301458y"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja307647x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/mz500759n"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.7b00411"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-36709-4"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reactfunctpolym.2022.105353"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/pola.26244"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmacrolett.6b00188"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.7b01335"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9NA00052F"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.201700060"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/bm501091p"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/cm402180t"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5PY00098J"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1080\/15583724.2021.1939372"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c01163"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3PY01276J"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1039\/D2BM01199A"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201002097"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2023.121135"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4AN01775G"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-015-9152-x"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1039\/C4BM00269E"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2024.112946"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202300594"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.7b00827"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01202"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1039\/C2PY20849K"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja402490j"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0PY01215G"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26113332"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6QM00135A"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc800317a"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.6b01397"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.202000303"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.8b00258"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.1c01295"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja1069932"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja102316a"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201705475"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc9004443"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3PY00991B"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5PY00969C"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2012.06.007"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma302499a"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5c05856"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b00802"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.4c00239"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma061420x"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj1730723"},{"key":"e_1_2_9_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-9861(59)90090-6"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b07626"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1319900111"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2016.00086"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-022-01209-6"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-43067-8"},{"key":"e_1_2_9_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-04749-8"}],"container-title":["Macromolecular Bioscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mabi.202500346","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mabi.202500346","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mabi.202500346","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:46:52Z","timestamp":1783010812000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mabi.202500346"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":77,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/mabi.202500346"],"URL":"https:\/\/doi.org\/10.1002\/mabi.202500346","archive":["Portico"],"relation":{},"ISSN":["1616-5187","1616-5195"],"issn-type":[{"value":"1616-5187","type":"print"},{"value":"1616-5195","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,30]]},"assertion":[{"value":"2025-06-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00346"}}