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Conventional wound dressings lack both real\u2010time monitoring capabilities and active therapeutic functionalities, limiting their effectiveness in dynamic wound environments. Herein, we report our proof\u2010of\u2010concept approach exploring the unique emission properties and antimicrobial activities of carbon nanodots (CNDs) for simultaneous detection and treatment of bacteria. This approach centers on the fabrication of well\u2010defined CND\u2010embedded poly(vinyl alcohol) (PVA) e\u2010spun nanofibrous mats, which are crosslinked with degradable boronic ester (BE) crosslinks. The BE\u2010CND\/PVA mats exhibit stimuli\u2010responsive degradation to pHs and hydrogen peroxide as well as pH\u2010responsive release of CNDs. Promisingly, the mats turn out to be hemocompatible with blood and biocompatible with skin cells. Furthermore, they exhibit notable antimicrobial activity against Gram\u2010negative bacteria and demonstrate great potential for real\u2010time monitoring of wound pH to assess the wound status. These results suggest that BE\u2010CND\/PVA mats could significantly enhance wound healing by providing localized therapeutic action, reducing the risk of bacterial infections, and enabling non\u2010invasive monitoring of wound progress.<\/jats:p>","DOI":"10.1002\/mabi.202500352","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T15:26:07Z","timestamp":1757345167000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Luminescent Electro\u2010Spun Nanofibers Crosslinked with Boronic Esters Exhibiting Controlled Release of Carbon Dots for Detection of Wound pHs and Enhanced Antimicrobial"],"prefix":"10.1002","volume":"25","author":[{"given":"Nishadi Dilkushi","family":"Lokuge","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry Concordia University  Montreal Quebec Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia 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