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Natural polysaccharide hydrogels, characterized by a three\u2010dimensional porous structure analogous to human tissues, have been extensively utilized in biomedical applications. Hydrogels fabricated from natural polysaccharides via photopolymerization enable the formation of scaffolds with precise three\u2010dimensional architectures. Exhibiting excellent biocompatibility, controlled degradability, and tunable mechanical and physicochemical properties, these photopolymerized polysaccharide hydrogels can construct tissue\u2010adaptable microenvironments matching the physiological requirements of specific tissues to support cellular activities and tissue regeneration. Consequently, their applications in tissue engineering and controlled drug release have garnered significant attention, demonstrating considerable potential across various contexts. This review, based on an analysis of domestic and international literature, summarizes the latest research progress on natural polysaccharide\u2010based photocrosslinked hydrogels in regenerative medicine. 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