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Conventional non\u2010degradable occluders are hampered by permanent foreign body retention, insufficient anatomical conformability, and sustained long\u2010term foreign\u2010body inflammatory stimulation. Fully biodegradable materials offer a novel approach for device advancement. This review summarizes the characteristics and composite modification technologies of poly\u2010p\u2010dioxanone (PPDO) and polylactic acid (PLA), analyzes the application advantages and latest research progress of biodegradable closure devices, discusses technical challenges and corresponding solutions, and prospects their development trends toward multi\u2010functionality and intellectualization. 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