{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:40:51Z","timestamp":1791092451187,"version":"4.1.0"},"reference-count":28,"publisher":"Wiley","issue":"22","license":[{"start":{"date-parts":[[2011,9,20]],"date-time":"2011-09-20T00:00:00Z","timestamp":1316476800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Macromol. Rapid Commun."],"published-print":{"date-parts":[[2011,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 32\u2010membered library of poly(2\u2010oxazoline)\u2010based hydrogels of the composition p<jats:bold>EtOx<\/jats:bold><jats:sub>m<\/jats:sub>\u2010p<jats:bold>PhOx<\/jats:bold><jats:sub>n<\/jats:sub>\u2010p<jats:bold>PBO<\/jats:bold><jats:sub>q<\/jats:sub> (<jats:italic>m<\/jats:italic>\/<jats:italic>n<\/jats:italic> = 150\/0, 100\/50, 50\/100, and 0\/150; <jats:italic>q<\/jats:italic> = 1.5\u201330) was prepared from 2\u2010ethyl\u2010 (<jats:bold>EtOx<\/jats:bold>), 2\u2010phenyl\u20102\u2010oxazoline (<jats:bold>PhOx<\/jats:bold>), and phenylene\u20101,3\u2010bis\u2010(2\u2010oxazoline) (<jats:bold>PBO<\/jats:bold>). The polymerizations were performed from ground monomer mixtures at 140 \u00b0C in a single\u2010mode microwave reactor in reaction times as short as 1 h. Purified hydrogels, containing no residual monomers, were obtained in yields of 95% or higher. Acid\u2010mediated hydrolysis rates as well as swelling degrees of the hydrogels were adjustable over a broad range; swelling degrees in water\/ethanol\/dichloromethane ranged from 0 to 13.8\/11.7\/20.0. The hydrogels could incorporate organic molecules according to in situ or post\u2010synthetic routines. Post\u2010synthetic routines enabled for the preparation of hydrogels from which the incorporated compounds were only released through diffusion processes if the solvent was changed or through hydrogel degradation if the pH was lowered.<\/jats:p>","DOI":"10.1002\/marc.201100409","type":"journal-article","created":{"date-parts":[[2011,9,20]],"date-time":"2011-09-20T08:22:04Z","timestamp":1316506924000},"page":"1815-1819","source":"Crossref","is-referenced-by-count":37,"title":["Synthesis of Poly(2\u2010oxazoline)\u2010Based Hydrogels with Tailor\u2010Made Swelling Degrees Capable of Stimuli\u2010Triggered Compound Release"],"prefix":"10.1002","volume":"32","author":[{"given":"Andrew M.","family":"Kelly","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Hecke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bianca","family":"Wirnsberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Wiesbrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2011,9,20]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(01)00203-4"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/185117a0"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1021\/bm015614q"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2007.02.015"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200250653"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1021\/cr000108x"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(89)90013-8"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1021\/bm034513k"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(97)00242-3"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(98)00042-8"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200902672"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(95)00004-R"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma00193a013"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma00207a002"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/macp.200390065"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/pola.10201"},{"key":"e_1_2_7_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200901607"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.02.057"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-007-3334-9"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201000283"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201000539"},{"key":"e_1_2_7_22_2","doi-asserted-by":"publisher","DOI":"10.1002\/marc.200400313"},{"key":"e_1_2_7_23_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma0474170"},{"key":"e_1_2_7_24_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma050437x"},{"key":"e_1_2_7_25_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma060952a"},{"key":"e_1_2_7_26_2","doi-asserted-by":"publisher","DOI":"10.1002\/pol.1966.110040405"},{"key":"e_1_2_7_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4628(20000906)77:10<2206::AID-APP14>3.0.CO;2-D"},{"key":"e_1_2_7_28_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0518(19970930)35:13<2711::AID-POLA16>3.0.CO;2-E"}],"container-title":["Macromolecular Rapid Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmarc.201100409","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/marc.201100409","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,10]],"date-time":"2023-10-10T03:04:24Z","timestamp":1696907064000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/marc.201100409"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9,20]]},"references-count":28,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2011,11,15]]}},"alternative-id":["10.1002\/marc.201100409"],"URL":"https:\/\/doi.org\/10.1002\/marc.201100409","archive":["Portico"],"relation":{},"ISSN":["1022-1336","1521-3927"],"issn-type":[{"value":"1022-1336","type":"print"},{"value":"1521-3927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,9,20]]}}}