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The monomer is prepared in a two\u2010step synthesis and can be polymerized in a well\u2010controlled manner under AROP conditions. Several poly(ethylene glycol) block and triblock copolymers are synthesized in a molecular weight range from 2\u2009700 to 11\u2009400 g mol<jats:sup>\u22121<\/jats:sup> with up to 11 mol% PyGA. The molecular weight distributions are monomodal with low dispersity (<jats:italic>\u0110<\/jats:italic> = <jats:italic>M<\/jats:italic><jats:sub>w<\/jats:sub>\/<jats:italic>M<\/jats:italic><jats:sub>n<\/jats:sub>) below 1.2. After the polymerization, the acid\u2010labile hexahydro\u2010pyrimidine rings can be conveniently cleaved in acidic media, liberating two secondary amines per PyGA monomer unit. The released 1,3\u2010diamine functionalities can be addressed via post\u2010polymerization modification and show complexation of copper(II) ions in aqueous solution. The compounds are promising for water\u2010soluble catalyst systems, the removal of transition metals from water, and as a building block for complexing polyethers for biomedical application.<\/jats:p>","DOI":"10.1002\/marc.201900057","type":"journal-article","created":{"date-parts":[[2019,3,20]],"date-time":"2019-03-20T12:22:53Z","timestamp":1553084573000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Aminal Protection of Epoxide Monomer Permits the Introduction of Multiple Secondary Amine Moieties at Poly(ethylene glycol)"],"prefix":"10.1002","volume":"40","author":[{"given":"Jan","family":"Blankenburg","sequence":"first","affiliation":[{"name":"Institute of Organic Chemistry Johannes Gutenberg University  Duesbergweg 10\u201314 55128 Mainz Germany"},{"name":"Graduate School Materials Science in Mainz (MAINZ)  Staudingerweg 9 55128 Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9916-3103","authenticated-orcid":false,"given":"Holger","family":"Frey","sequence":"additional","affiliation":[{"name":"Institute of Organic Chemistry Johannes Gutenberg University  Duesbergweg 10\u201314 55128 Mainz Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,3,20]]},"reference":[{"key":"e_1_2_5_1_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00441"},{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2005.06.001"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1033"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.polymer.2016.10.015"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201100027"},{"key":"e_1_2_5_5_2","doi-asserted-by":"publisher","DOI":"10.1039\/c2py00489e"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma702458g"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/marc.200900472"},{"key":"e_1_2_5_6_3","doi-asserted-by":"publisher","DOI":"10.1039\/c2py00489e"},{"key":"e_1_2_5_6_4","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b04548"},{"key":"e_1_2_5_6_5","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.8b02639"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200801951"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201200307"},{"key":"e_1_2_5_8_2","doi-asserted-by":"publisher","DOI":"10.1039\/c3py00747b"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma501367b"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc9600123"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1021\/acsmacrolett.6b00830"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/ma901745d"},{"key":"e_1_2_5_11_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma902245d"},{"key":"e_1_2_5_11_3","doi-asserted-by":"publisher","DOI":"10.1021\/ma300292m"},{"key":"e_1_2_5_11_4","doi-asserted-by":"publisher","DOI":"10.1002\/pola.28988"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.5b00556"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/macp.1994.021950111"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1021\/ma0354039"},{"key":"e_1_2_5_13_3","doi-asserted-by":"publisher","DOI":"10.1021\/ma300249c"},{"key":"e_1_2_5_13_4","doi-asserted-by":"publisher","DOI":"10.1039\/C7PY01613A"},{"key":"e_1_2_5_13_5","first-page":"403","volume":"55","author":"Song J.","year":"2019","journal-title":"Polym. 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