{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:26:01Z","timestamp":1791404761587,"version":"4.3.3"},"reference-count":61,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T00:00:00Z","timestamp":1713916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Macromol. Rapid Commun."],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Crescent\u2010shaped hydrogel microparticles are shown to template uniform volume aqueous droplets upon simple mixing with aqueous and oil media for various bioassays. This emerging \u201clab on a particle\u201d technique requires hydrogel particles with tunable material properties and dimensions. The crescent shape of the particles is attained by aqueous two\u2010phase separation of polymers followed by photopolymerization of the curable precursor. In this work, the phase separation of poly(ethylene glycol) diacrylate (PEGDA,\n                    <jats:italic>M<\/jats:italic>\n                    <jats:sub>w<\/jats:sub>\n                    700) and dextran (\n                    <jats:italic>M<\/jats:italic>\n                    <jats:sub>w<\/jats:sub>\n                    40\u00a0000) for tunable manufacturing of crescent\u2010shaped particles is investigated. The particles\u2019 morphology is precisely tuned by following a phase diagram, varying the UV intensity, and adjusting the flow rates of various streams. The fabricated particles with variable dimensions\u00a0encapsulate uniform aqueous droplets upon mixing with an oil phase. The particles are fluorescently labeled with red and blue emitting dyes at variable concentrations to produce six color\u2010coded particles. The blue fluorescent dye shows a moderate response to the pH change. The fluorescently labeled particles are able to tolerate an extremely acidic solution (pH 1) but disintegrate within an extremely basic solution (pH 14). The particle\u2010templated droplets are able to effectively retain the disintegrating particle and the fluorescent signal at pH 14.\n                  <\/jats:p>","DOI":"10.1002\/marc.202300721","type":"journal-article","created":{"date-parts":[[2024,4,14]],"date-time":"2024-04-14T03:29:28Z","timestamp":1713065368000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Fabrication of Crescent Shaped Microparticles for Particle Templated Droplet Formation"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-7574-3490","authenticated-orcid":false,"given":"Yimin","family":"Yang","sequence":"first","affiliation":[{"name":"Control and Manipulation of Microscale Living Objects Department of Electrical Engineering TUM School of Computation, Information and Technology TranslaTUM \u2013 Center for Translational Cancer Research Technical University of Munich  Einsteinstra\u00dfe 25 81675 Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergei I.","family":"Vagin","sequence":"additional","affiliation":[{"name":"WACKER\u2010Chair of Macromolecular Chemistry Department of Chemistry TUM School of Natural Sciences Technical University of Munich  Lichtenbergstra\u00dfe 4 85748 Garching Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Rieger","sequence":"additional","affiliation":[{"name":"WACKER\u2010Chair of Macromolecular Chemistry Department of Chemistry TUM School of Natural Sciences Technical University of Munich  Lichtenbergstra\u00dfe 4 85748 Garching Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4498-1643","authenticated-orcid":false,"given":"Ghulam","family":"Destgeer","sequence":"additional","affiliation":[{"name":"Control and Manipulation of Microscale Living Objects Department of Electrical Engineering TUM School of Computation, Information and Technology TranslaTUM \u2013 Center for Translational Cancer Research Technical University of Munich  Einsteinstra\u00dfe 25 81675 Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c08675"},{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1507"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1641"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/nn401661d"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201006089"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1039\/b805456h"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2013.046"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-020-0466-7"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1966"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3LC51327K"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.7b00620"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c10473"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7LC00005G"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5LC01341K"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc21147e"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.201900188"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b04681"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10404-017-1889-4"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.201900307"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/C3LC51202A"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202016154"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adk2864"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23773-x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10404-021-02487-y"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.1c00666"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/gels9100790"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1985"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c02307"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1LC01098K"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-90255-x"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.2c01415"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2016.154"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5LC00614G"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c11420"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0LC00698J"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abb9023"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b01759"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1LC00344E"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-023-01685-z"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.0c04184"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c05857"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1021\/ar4001263"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00263G"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3LC00711A"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201904889"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201811374"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/macp.201600422"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201102715"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12575-016-0048-8"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9CS00466A"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.1c04487"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fsens.2022.840130"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.1c02076"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat1617"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201701036"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja802157y"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1039\/C6LC00254D"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2017.09.081"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10392"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0LC01294G"},{"key":"e_1_2_9_61_1","first-page":"14","volume":"793","author":"Yang Y.","year":"2023","journal-title":"Nat. Commun."}],"container-title":["Macromolecular Rapid Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/marc.202300721","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,8]],"date-time":"2024-07-08T11:39:11Z","timestamp":1720438751000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/marc.202300721"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,24]]},"references-count":61,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1002\/marc.202300721"],"URL":"https:\/\/doi.org\/10.1002\/marc.202300721","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.10.06.561257","asserted-by":"object"}]},"ISSN":["1022-1336","1521-3927"],"issn-type":[{"value":"1022-1336","type":"print"},{"value":"1521-3927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,24]]},"assertion":[{"value":"2023-12-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2300721"}}