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In this work, thin hydrogel layers of \u2248100\u00a0nm thickness (nanogels) are synthesized and characterized for their structural irregularities, as they represent the surface of macrogels. The nanogels contain a main\u2010chain responsiveness (thermo responsive) and a responsiveness in the cross\u2010linking points (redox responsive). By combining data from ellipsometry using box\u2010model and two\u2010segment\u2010model analysis, as well as atomic force microscopy, a more defined model of the nanogel surface can be developed. Starting with a more densely cross\u2010linked network at the silica wafer surface, the density of cross\u2010linking gradually decreases toward the hydrogel\u2013solvent interface. Thermo\u2010responsive behavior of the main chain affects the entire network equally as all chain segments change solubility. Cross\u2010linker\u2010based redox\u2010responsiveness, on the other hand, is only governed by the inner, more cross\u2010linked layers of the network. Such dual responsive nanogels hence allow for developing a more detailed model of a hydrogel surface from free radical polymerization. It provides a better understanding of structural defects in hydrogels and how they are affected by responsive functionalities.<\/jats:p>","DOI":"10.1002\/marc.202400049","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T03:58:50Z","timestamp":1714449530000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Surface Topology of Redox\u2010 and Thermoresponsive Nanogel Droplets"],"prefix":"10.1002","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-8472-2850","authenticated-orcid":false,"given":"Doreen","family":"Hofmann","sequence":"first","affiliation":[{"name":"Leibniz\u2010Institut f\u00fcr Polymerforschung Dresden e.V.  Hohe Stra\u00dfe 6 01069 Dresden Germany"},{"name":"Faculty of Chemistry and Food Chemistry Technische Universit\u00e4t Dresden  01069 Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2440-2536","authenticated-orcid":false,"given":"Dmitrii","family":"Sychev","sequence":"additional","affiliation":[{"name":"Leibniz\u2010Institut f\u00fcr Polymerforschung Dresden e.V.  Hohe Stra\u00dfe 6 01069 Dresden Germany"},{"name":"Chair of Physical Chemistry of Polymeric Materials Technische Universit\u00e4t Dresden  01069 Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6276-6509","authenticated-orcid":false,"given":"Zlata","family":"Zagradska\u2010Paromova","sequence":"additional","affiliation":[{"name":"Leibniz\u2010Institut f\u00fcr Polymerforschung Dresden e.V.  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