{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:19:19Z","timestamp":1790277559185,"version":"4.1.0"},"reference-count":54,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T00:00:00Z","timestamp":1736726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000265","name":"Medical Research Council","doi-asserted-by":"publisher","award":["MR\/T023686"],"award-info":[{"award-number":["MR\/T023686"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002446","name":"Catholic University of Pusan","doi-asserted-by":"publisher","award":["I53C22001300001"],"award-info":[{"award-number":["I53C22001300001"]}],"id":[{"id":"10.13039\/501100002446","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Macromol. Rapid Commun."],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    Antimicrobial resistance poses a growing threat to public health globally. Multidrug resistant\n                    <jats:italic>Pseudomonas (P.) aeruginosa<\/jats:italic>\n                    is detected in many infected wounds and is very challenging to treat with antibiotics. An alternative to antibiotics is to use bacteriophages, highly specific viruses able to kill even resistant bacteria. This work incorporates anti\u2010\n                    <jats:italic>P. aeruginosa Neko<\/jats:italic>\n                    phages into monoaxial and coaxial electrospun fibers to explore their potential for treating infected wounds. Phages are blended with polyvinyl alcohol (PVA) solution and either processed directly into fibers or used as the core in coaxial electrospinning with polyvinylpyrrolidone (PVP) and PVP\/ethyl cellulose (EC) shell solutions. Coaxial fibers stored at \u221220\u00a0\u00b0C show promising stability results, with negligible phage titer loss after 6 months of storage. Phage release can be controlled by varying the shell composition. Coaxial fibers with PVP as the shell (PVA\/Su PVP + phage) demonstrate immediate release while fibers with PVP\/EC as the shell (PVA\/Su PVP\/EC + phage) display extended\u2010release. The antibacterial efficacy of phage lysate and phage\u2010loaded fibers is studied by isothermal calorimetry and found to be unaffected by electrospinning. Thus, it appears that phage\u2010loaded electrospun fibers merit further investigation as potential wound dressing materials.\n                  <\/jats:p>","DOI":"10.1002\/marc.202400744","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T06:46:26Z","timestamp":1736750786000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Anti\u2010Pseudomonas Aeruginosa Bacteriophage Loaded Electrospun Fibers for Antibacterial Wound Dressings"],"prefix":"10.1002","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7623-9132","authenticated-orcid":false,"given":"Tian","family":"Ju","sequence":"first","affiliation":[{"name":"UCL School of Pharmacy University College London  29\u201339 Brunswick Square London WC1N 1AX UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1283-4228","authenticated-orcid":false,"given":"Jixuan","family":"Li","sequence":"additional","affiliation":[{"name":"UCL School of Pharmacy University College London  29\u201339 Brunswick Square London WC1N 1AX UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-6492-989X","authenticated-orcid":false,"given":"Andrew","family":"Weston","sequence":"additional","affiliation":[{"name":"UCL School of Pharmacy University College London  29\u201339 Brunswick Square London WC1N 1AX UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0120-7885","authenticated-orcid":false,"given":"Giovanni","family":"Satta","sequence":"additional","affiliation":[{"name":"Centre for Clinical Microbiology Royal Free Campus University College London  Rowland Hill Street London NW3 2PF UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4574-4512","authenticated-orcid":false,"given":"Sara","family":"Bolognini","sequence":"additional","affiliation":[{"name":"Department of Biology University of Pisa  Via San Zeno 39 Pisa 56127 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0688-034X","authenticated-orcid":false,"given":"Mariagrazia","family":"Di Luca","sequence":"additional","affiliation":[{"name":"Department of Biology University of Pisa  Via San Zeno 39 Pisa 56127 Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1000-3208","authenticated-orcid":false,"given":"Simon","family":"Gaisford","sequence":"additional","affiliation":[{"name":"UCL School of Pharmacy University College London  29\u201339 Brunswick Square London WC1N 1AX UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3066-2860","authenticated-orcid":false,"given":"Gareth R.","family":"Williams","sequence":"additional","affiliation":[{"name":"UCL School of Pharmacy University College London  29\u201339 Brunswick Square London WC1N 1AX UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,13]]},"reference":[{"key":"e_1_2_9_1_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0"},{"key":"e_1_2_9_2_1","volume-title":"WHO Bacterial Priority Pathogens List, 2024: bacterial pathogens of public health importance to guide research, development and strategies to prevent and control antimicrobial resistance","year":"2024"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/5.2.279"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics10101162"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.104895"},{"key":"e_1_2_9_6_1","volume-title":"The Good Virus: The Untold Story of Phages: the Most Abundant Life Forms on Earth and what They Can Do for Us","author":"Ireland T.","year":"2023"},{"key":"e_1_2_9_7_1","volume-title":"Bacteriophages","author":"Kasman L. 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