{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T02:54:42Z","timestamp":1789786482974,"version":"4.0.1"},"reference-count":215,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T00:00:00Z","timestamp":1449100800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["#81402396"],"award-info":[{"award-number":["#81402396"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Mass Spectrometry Reviews"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec><jats:label\/><jats:p>Applications of mass spectrometry (MS) are rapidly expanding and encompass molecular and cellular biology. MS aids in the analysis of <jats:italic>in vivo<\/jats:italic> global molecular alterations, identifying potential biomarkers which may improve diagnosis and treatment of various pathologies. MS has added new dimensionality to medical research. Pioneering gynecologists now study molecular mechanisms underlying female reproductive pathology with MS\u2010based tools. Although benign gynecologic disorders including endometriosis, adenomyosis, leiomyoma, and polycystic ovarian syndrome (PCOS) carry low mortality rates, they cause significant physical, mental, and social detriments. Additionally, some benign disorders are unfortunately associated with malignancies. MS\u2010based technology can detect malignant changes in formerly benign proteomes and metabolomes with distinct advantages of speed, sensitivity, and specificity. We present the use of MS in proteomics and metabolomics, and summarize the current understanding of the molecular pathways concerning female reproductive anatomy. Highlight discoveries of novel protein and metabolite biomarkers via MS\u2010based technology, we underscore the clinical application of these techniques in the diagnosis and management of benign gynecological disorders. \u00a9 2015 Wiley Periodicals, Inc. Mass Spec Rev 36:450\u2013470, 2017<\/jats:p><\/jats:sec>","DOI":"10.1002\/mas.21484","type":"journal-article","created":{"date-parts":[[2015,12,3]],"date-time":"2015-12-03T15:44:42Z","timestamp":1449157482000},"page":"450-470","source":"Crossref","is-referenced-by-count":21,"title":["A mass spectrometric insight into the origins of benign gynecological disorders"],"prefix":"10.1002","volume":"36","author":[{"given":"Huiliang","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Gynecology and Obstetrics Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China"},{"name":"Department of Orthopedics, West China Hospital Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne Bond","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Thomas Jefferson University Hospital Philadelphia PA 19107"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Surgery, Emergency Medicine Kaiser Santa Clara Medical Center, Affiliate of Stanford University Stanford CA 94305"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Xuan","sequence":"additional","affiliation":[{"name":"The State Key Laboratory of Biotherapy West China Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengtao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linjie","family":"Zhao","sequence":"additional","affiliation":[{"name":"The State Key Laboratory of Biotherapy West China Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongyue","family":"Luo","sequence":"additional","affiliation":[{"name":"College of Biological Sciences Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiao","family":"Lin","sequence":"additional","affiliation":[{"name":"College of Biological Sciences Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Ren","sequence":"additional","affiliation":[{"name":"College of Biological Sciences Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Gynecology and Obstetrics Key Laboratory of Obstetrics and Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuquan","family":"Wei","sequence":"additional","affiliation":[{"name":"The State Key Laboratory of Biotherapy West China Hospital, Sichuan University Chengdu Sichuan 610041 P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml015"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2007.02157.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mefs.2010.10.002"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.53.37620"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den450"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.4.767"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr010202t"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1534-5807(03)00090-X"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.5.9.2712"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12565-011-0127-5"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature08504"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.2.426"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.5.448"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(87)90247-6"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2006.01.016"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdra.20488"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr8002936"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2008-0322"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep009"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.05.027"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.78.3.736"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr9004426"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(87)90512-0"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/17.1.69"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der345"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr100008e"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem380"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj20021856"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-1981(02)00336-0"},{"issue":"2","key":"e_1_2_8_31_1","first-page":"s19","article-title":"Clinical metabolomics: The next stage of clinical biochemistry","volume":"10","author":"D'Alessandro A","year":"2012","journal-title":"Blood Transfus"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2010.03.017"},{"key":"e_1_2_8_33_1","doi-asserted-by":"crossref","first-page":"13784","DOI":"10.1016\/S0021-9258(18)67088-7","article-title":"A calcium\u2010dependent 35\u2010kilodalton substrate for epidermal growth factor receptor\/kinase isolated from normal tissue","volume":"261","author":"De BK","year":"1986","journal-title":"J Biol Chem"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200400920"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmg010"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/156795"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(93)90044-O"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2mb25353d"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2012.08.009"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400311"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1159\/000051853"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2011.176396"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(01)02955-7"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/09513590902730796"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2006.01.012"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1532"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des127"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmm034"},{"key":"e_1_2_8_49_1","first-page":"30","article-title":"Human uterine leiomyoma cells: Binding and growth responses to epidermal growth factor, platelet\u2010derived growth factor, and insulin","volume":"60","author":"Fayed YM","year":"1989","journal-title":"Lab Invest"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02118305"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsgi.2005.01.027"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr060680q"},{"key":"e_1_2_8_53_1","first-page":"32","article-title":"Proteomic analysis of peritoneal fluid in fertile and infertile women with endometriosis","volume":"54","author":"Ferrero S","year":"2009","journal-title":"J Reprod Med"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.08.039"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200600469"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-12-0718"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1230217"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-4889(97)00038-4"},{"key":"e_1_2_8_59_1","doi-asserted-by":"crossref","first-page":"489","DOI":"10.18388\/abp.2012_2082","article-title":"Role of heat\u2010shock proteins and cobalamine in maintaining methionine synthase activity","volume":"59","author":"Grabowski M","year":"2012","journal-title":"Acta Biochim Pol"},{"key":"e_1_2_8_60_1","first-page":"538","article-title":"Treatment of adenomyosis with long\u2010term GnRH analogues: A case report","volume":"78","author":"Grow DR","year":"1991","journal-title":"Obstet Gynecol"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gah206"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2008.07.024"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0239fje"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr070277z"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2008.12.026"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-006-0173-8"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.11.011"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(89)81779-X"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm043"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2009.03.005"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(92)90984-R"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.114.5.909"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(95)02304-6"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719107309690"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0220"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2013.02.009"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00000615"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2012.683064"},{"key":"e_1_2_8_79_1","first-page":"1445","article-title":"Antisense RNA inhibition of phosphoprotein p18 expression abrogates the transformed phenotype of leukemic cells","volume":"56","author":"Jeha S","year":"1996","journal-title":"Cancer Res"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0320655"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2007.19"},{"key":"e_1_2_8_82_1","first-page":"324","article-title":"Study on the relationship between altered expression of annexin A4 and endometrial receptivity during the implantation window in infertile patients with endometriosis","volume":"47","author":"Jiang YL","year":"2012","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.08.078"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.032425"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2004-0489"},{"key":"e_1_2_8_86_1","first-page":"719","article-title":"Grade 2 endometrioid adenocarcinoma arising from adenomyosis of the uterus: Report of a case","volume":"31","author":"Kazandi M","year":"2010","journal-title":"Eur J Gynaecol Oncol"},{"key":"e_1_2_8_87_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093805"},{"key":"e_1_2_8_88_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dei135"},{"key":"e_1_2_8_89_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113596"},{"key":"e_1_2_8_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.04.042"},{"key":"e_1_2_8_91_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200408047"},{"key":"e_1_2_8_92_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2012.2184"},{"key":"e_1_2_8_93_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.5.741"},{"key":"e_1_2_8_94_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dem241"},{"key":"e_1_2_8_95_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1108009"},{"key":"e_1_2_8_96_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199205143262006"},{"key":"e_1_2_8_97_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-67-2-334"},{"key":"e_1_2_8_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(80)91018-2"},{"key":"e_1_2_8_99_1","doi-asserted-by":"publisher","DOI":"10.1097\/00029330-200805020-00012"},{"key":"e_1_2_8_100_1","first-page":"2190","article-title":"Increased expression of stathmin in eutopic endometrium of patients with endometriosis","volume":"123","author":"Li CY","year":"2010","journal-title":"Chin Med J (Engl)"},{"key":"e_1_2_8_101_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.06-7464rev"},{"key":"e_1_2_8_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.24.14535"},{"key":"e_1_2_8_103_1","doi-asserted-by":"publisher","DOI":"10.1039\/C2MB05453A"},{"key":"e_1_2_8_104_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1996.d01-440.x"},{"key":"e_1_2_8_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.06.081"},{"key":"e_1_2_8_106_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.08.095"},{"key":"e_1_2_8_107_1","first-page":"514","article-title":"Comparative proteomics analysis of human adenomyosis","volume":"43","author":"Liu HY","year":"2008","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"e_1_2_8_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-012-2700-0"},{"key":"e_1_2_8_109_1","first-page":"702","article-title":"Endometrium in women with polycystic ovary syndrome during the window of implantation","volume":"57","author":"Lopes IM","year":"2011","journal-title":"Rev Assoc Med Bras"},{"key":"e_1_2_8_110_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1991.tb37848.x"},{"key":"e_1_2_8_111_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gam036"},{"key":"e_1_2_8_112_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.32.20306"},{"key":"e_1_2_8_113_1","doi-asserted-by":"publisher","DOI":"10.2116\/analsci.19.3"},{"key":"e_1_2_8_114_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1996.tb00914.x"},{"key":"e_1_2_8_115_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-198512000-00007"},{"key":"e_1_2_8_116_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.063305"},{"key":"e_1_2_8_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1642-431X(12)60027-8"},{"key":"e_1_2_8_118_1","doi-asserted-by":"publisher","DOI":"10.2165\/00148581-200608050-00004"},{"key":"e_1_2_8_119_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmq009"},{"key":"e_1_2_8_120_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-6339"},{"key":"e_1_2_8_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2010.04.016"},{"key":"e_1_2_8_122_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00220a034"},{"key":"e_1_2_8_123_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi400060e"},{"key":"e_1_2_8_124_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600929"},{"key":"e_1_2_8_125_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03346575"},{"key":"e_1_2_8_126_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000126373.52450.32"},{"key":"e_1_2_8_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1095-6433(01)00522-0"},{"key":"e_1_2_8_128_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-007-0725-3"},{"key":"e_1_2_8_129_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0365-05962011000100015"},{"key":"e_1_2_8_130_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10194-011-0298-4"},{"key":"e_1_2_8_131_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dms059"},{"key":"e_1_2_8_132_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2400"},{"key":"e_1_2_8_133_1","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200900055"},{"key":"e_1_2_8_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-7827(01)00003-0"},{"key":"e_1_2_8_135_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1994.63062048.x"},{"key":"e_1_2_8_136_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1016294"},{"key":"e_1_2_8_137_1","doi-asserted-by":"publisher","DOI":"10.1038\/4551054a"},{"key":"e_1_2_8_138_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008469-199504000-00002"},{"key":"e_1_2_8_139_1","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0b013e31827aa0bb"},{"key":"e_1_2_8_140_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra000763"},{"key":"e_1_2_8_141_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep382"},{"key":"e_1_2_8_142_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(97)81470-7"},{"key":"e_1_2_8_143_1","doi-asserted-by":"publisher","DOI":"10.1007\/PL00000910"},{"key":"e_1_2_8_144_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.103.10.1410"},{"key":"e_1_2_8_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.01.093"},{"key":"e_1_2_8_146_1","first-page":"59","article-title":"Mass spectrometry\u2010based proteomics for translational research: A technical overview","volume":"85","author":"Paulo JA","year":"2012","journal-title":"Yale J Biol Med"},{"key":"e_1_2_8_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70404-1"},{"key":"e_1_2_8_148_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.dad.0000200009.02939.cc"},{"key":"e_1_2_8_149_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113595"},{"key":"e_1_2_8_150_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1196-1259"},{"key":"e_1_2_8_151_1","doi-asserted-by":"publisher","DOI":"10.1002\/jlb.55.3.349"},{"key":"e_1_2_8_152_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-7-15"},{"key":"e_1_2_8_153_1","first-page":"112","article-title":"Mass spectrometry in medicine and biotechnology","author":"Polunina TA","year":"2013","journal-title":"Zh Mikrobiol Epidemiol Immunobiol"},{"key":"e_1_2_8_154_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.69.1.419"},{"key":"e_1_2_8_155_1","doi-asserted-by":"publisher","DOI":"10.3109\/07357900009012204"},{"key":"e_1_2_8_156_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr300997c"},{"key":"e_1_2_8_157_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr030"},{"key":"e_1_2_8_158_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2004.03.032"},{"key":"e_1_2_8_159_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr100657s"},{"key":"e_1_2_8_160_1","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200900094"},{"key":"e_1_2_8_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)56027-0"},{"key":"e_1_2_8_162_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2009.12.022"},{"key":"e_1_2_8_163_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.169.3.1500"},{"key":"e_1_2_8_164_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.028415"},{"key":"e_1_2_8_165_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-7-40"},{"key":"e_1_2_8_166_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1995.0865a.x"},{"key":"e_1_2_8_167_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.20187"},{"key":"e_1_2_8_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)57506-2"},{"key":"e_1_2_8_169_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719111432867"},{"key":"e_1_2_8_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2004.02.103"},{"key":"e_1_2_8_171_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1996.0070"},{"key":"e_1_2_8_172_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2008.03.001"},{"key":"e_1_2_8_173_1","first-page":"19","article-title":"Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas","volume":"59","author":"Schoenmakers EF","year":"1999","journal-title":"Cancer Res"},{"key":"e_1_2_8_174_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719109337165"},{"key":"e_1_2_8_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.12.121"},{"key":"e_1_2_8_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0378(98)00079-5"},{"key":"e_1_2_8_177_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161207782794167"},{"key":"e_1_2_8_178_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/6.9.829"},{"key":"e_1_2_8_179_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx800459q"},{"key":"e_1_2_8_180_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.44.27266"},{"key":"e_1_2_8_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)84915-3"},{"key":"e_1_2_8_182_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0941fje"},{"key":"e_1_2_8_183_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1044-0305(00)00167-7"},{"key":"e_1_2_8_184_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der263"},{"key":"e_1_2_8_185_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.8.5958"},{"key":"e_1_2_8_186_1","doi-asserted-by":"publisher","DOI":"10.1021\/pr3000317"},{"key":"e_1_2_8_187_1","doi-asserted-by":"publisher","DOI":"10.2741\/1045"},{"key":"e_1_2_8_188_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2007.05450.x"},{"key":"e_1_2_8_189_1","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200401022"},{"key":"e_1_2_8_190_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1991.tb08277.x"},{"key":"e_1_2_8_191_1","doi-asserted-by":"publisher","DOI":"10.1262\/jrd.18129"},{"key":"e_1_2_8_192_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.01148"},{"key":"e_1_2_8_193_1","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200600743"},{"key":"e_1_2_8_194_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.079236"},{"key":"e_1_2_8_195_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-007-5896-4_1"},{"key":"e_1_2_8_196_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00410a024"},{"key":"e_1_2_8_197_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmn053"},{"key":"e_1_2_8_198_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.1041420110"},{"key":"e_1_2_8_199_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.5.1142"},{"key":"e_1_2_8_200_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des152"},{"key":"e_1_2_8_201_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1210581"},{"key":"e_1_2_8_202_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2008.01.018"},{"key":"e_1_2_8_203_1","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2008.100"},{"key":"e_1_2_8_204_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-3083"},{"key":"e_1_2_8_205_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-2724"},{"key":"e_1_2_8_206_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(88)81330-5"},{"key":"e_1_2_8_207_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.03.061"},{"key":"e_1_2_8_208_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dep015"},{"key":"e_1_2_8_209_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.19.8539"},{"key":"e_1_2_8_210_1","doi-asserted-by":"crossref","first-page":"2794","DOI":"10.4049\/jimmunol.151.5.2794","article-title":"Conversion of vitamin D3 binding protein (group\u2010specific component) to a macrophage activating factor by the stepwise action of beta\u2010galactosidase of B cells and sialidase of T cells","volume":"151","author":"Yamamoto N","year":"1993","journal-title":"J Immunol"},{"key":"e_1_2_8_211_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-9-73"},{"key":"e_1_2_8_212_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.20408"},{"key":"e_1_2_8_213_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.01.028"},{"key":"e_1_2_8_214_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-10-153"},{"key":"e_1_2_8_215_1","doi-asserted-by":"publisher","DOI":"10.1177\/147323001103900406"},{"key":"e_1_2_8_216_1","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M112.017988"}],"container-title":["Mass Spectrometry Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmas.21484","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmas.21484","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mas.21484","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:08:24Z","timestamp":1760954904000},"score":1,"resource":{"primary":{"URL":"https:\/\/analyticalsciencejournals.onlinelibrary.wiley.com\/doi\/10.1002\/mas.21484"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,3]]},"references-count":215,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1002\/mas.21484"],"URL":"https:\/\/doi.org\/10.1002\/mas.21484","archive":["Portico"],"relation":{},"ISSN":["0277-7037","1098-2787"],"issn-type":[{"value":"0277-7037","type":"print"},{"value":"1098-2787","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,3]]}}}