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Given wild animals can harbor antimicrobial\u2010resistant bacteria (ARB), we investigated their presence in 11 fecal samples from wild animals using deoxycholate hydrogen sulfide lactose agar with or without cefotaxime (CTX, 1\u2009mg\/L). Thus, we isolated CTX\u2010resistant <jats:italic>Escherichia coli<\/jats:italic> from two Japanese red fox fecal samples. One strain was O83:H42\u2010ST1485\u2010fimH58 CTX\u2010M\u201055\u2010producing <jats:italic>E. coli<\/jats:italic> carrying the genes <jats:italic>aph(3\u2033)\u2010Ib<\/jats:italic>, <jats:italic>aph(3\u2032)\u2010Ia<\/jats:italic>, <jats:italic>aph(6)\u2010Id<\/jats:italic>, <jats:italic>mdf<\/jats:italic>(A), <jats:italic>sitABCD<\/jats:italic>, <jats:italic>sul<\/jats:italic>2, <jats:italic>tet<\/jats:italic>(A), and <jats:italic>tet<\/jats:italic>(B), whereas the other was O25:H4\u2010ST131\u2010fimH30 CTX\u2010M\u201014<jats:bold>\u2010<\/jats:bold>producing <jats:italic>E. coli<\/jats:italic> carrying <jats:italic>mdf<\/jats:italic>(A) and <jats:italic>sitABCD<\/jats:italic> and showing fluoroquinolone resistance. Thus, the presence of extended\u2010spectrum \u03b2\u2010lactamase producers in wild foxes suggests a spillover of ARB from human activities to these wild animals.<\/jats:p>","DOI":"10.1002\/mbo3.1317","type":"journal-article","created":{"date-parts":[[2022,9,19]],"date-time":"2022-09-19T13:00:23Z","timestamp":1663592423000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Isolation of extended\u2010spectrum \u03b2\u2010lactamase\u2010producing <i>Escherichia coli<\/i> from Japanese red fox (<i>Vulpes vulpes japonica<\/i>)"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6556-9674","authenticated-orcid":false,"given":"Tetsuo","family":"Asai","sequence":"first","affiliation":[{"name":"Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences Gifu University Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0403-6858","authenticated-orcid":false,"given":"Michiyo","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Applied Veterinary Sciences, United Graduate School of Veterinary Sciences Gifu University Gifu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7860-7409","authenticated-orcid":false,"given":"Tsutomu","family":"Omatsu","sequence":"additional","affiliation":[{"name":"Crisis Management Unit, Center for Infectious Diseases Epidemiology and Prevention Research Tokyo University of Agriculture and Technology Fuchu\u2010shi Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masato","family":"Yoshikawa","sequence":"additional","affiliation":[{"name":"Division of Environment Conservation, Institute of Agriculture Tokyo University of Agriculture and Technology Fuchu\u2010shi Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5379-1622","authenticated-orcid":false,"given":"Toshifumi","family":"Minamoto","sequence":"additional","affiliation":[{"name":"Division of Environment Conservation, Institute of Agriculture Tokyo University of Agriculture and Technology Fuchu\u2010shi Tokyo Japan"},{"name":"Department of Human Environmental Science, Graduate School of Human Development and Environment Kobe University Kobe Hyogo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,9,19]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1292\/jvms.19-0554"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.3176"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02824-14"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01604-13"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/112.9.1726"},{"key":"e_1_2_10_7_1","unstructured":"Clinical_and_Laboratory_Standards_Institute. 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