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No Enterobacteriales carrying carbapenemases or resistance against colistin were detected. Fifty\u2010four ESBL\u2010producing <jats:italic>Escherichia coli<\/jats:italic> and five ESBL\u2010producing <jats:italic>Klebsiella pneumoniae<\/jats:italic> isolates were identified in 52 of the samples, of which 52 <jats:italic>E. coli<\/jats:italic> and 4 <jats:italic>K. pneumoniae<\/jats:italic> yielded passed sequencing results. Fifty of the <jats:italic>E. coli<\/jats:italic> had ESBL phenotype and genotype harboring <jats:italic>bla<\/jats:italic><jats:sub>CTX\u2010M<\/jats:sub> genes, of which 88.5% (<jats:italic>n<\/jats:italic>\u2009=\u200946) were the <jats:italic>bla<\/jats:italic><jats:sub>CTX\u2010M\u201015<\/jats:sub> gene, commonly found on the African continent. Furthermore, the genetic context around <jats:italic>bla<\/jats:italic><jats:sub>CTX\u2010M\u201015<\/jats:sub> was similar between isolates, being colocalized with IS<jats:italic>Kpn19<\/jats:italic>. In contrast, cgMLST analysis of the <jats:italic>E. coli<\/jats:italic> harboring ESBL genes revealed a genetic distribution over a large fraction of the currently known existing <jats:italic>E. coli<\/jats:italic> populations in the Gambia. Hooded vultures in the Gambia thus have a high ESBL <jats:italic>E. coli<\/jats:italic>\u2010prevalence (&gt;50%) with low diversity regarding key resistance genes. Furthermore, given the urban presence and frequent interactions between hooded vultures and humans, data from this study implies hooded vultures as potential vectors contributing to the further dissemination of antibiotic\u2010resistance genes.<\/jats:p>","DOI":"10.1002\/mbo3.1349","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T14:24:30Z","timestamp":1679581470000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["High prevalence of <i>bla<\/i><sub>CTX\u2010M\u201015<\/sub> type extended\u2010spectrum beta\u2010lactamases in Gambian hooded vultures (<i>Necrosyrtes monachus<\/i>): A threatened species with substantial human interaction"],"prefix":"10.1002","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1707-2655","authenticated-orcid":false,"given":"Hanna","family":"Woksepp","sequence":"first","affiliation":[{"name":"Department of Research Region Kalmar County Kalmar Sweden"},{"name":"Department of Chemistry and Biomedical Sciences Linnaeus University Kalmar Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fagimba","family":"Camara","sequence":"additional","affiliation":[{"name":"Department of Wildlife Management, Abuko The West African Birds Study, Association (WABSA) Serrekunda Gambia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonas","family":"Bonnedahl","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Clinical Sciences Link\u00f6ping University Link\u00f6ping Sweden"},{"name":"Department of Infectious Diseases Region Kalmar County Kalmar Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,3,23]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsbl.2016.0137"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgar.2016.10.005"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.000192"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.watres.2019.06.073"},{"key":"e_1_2_10_6_1","unstructured":"BirdLife International. 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