{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T22:20:44Z","timestamp":1788906044503,"version":"build-2803163510"},"reference-count":40,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T00:00:00Z","timestamp":1489449600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T00:00:00Z","timestamp":1489449600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MicrobiologyOpen"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    New agents that are effective against common pathogens are needed particularly for those resistant to conventional antimicrobial agents. Essential oils (EOs) are known for their antimicrobial activity. Using the broth microdilution method, we showed that (1) two unique blends of\n                    <jats:italic>Cinnamomum zeylanicum<\/jats:italic>\n                    ,\n                    <jats:italic>Daucus carota<\/jats:italic>\n                    ,\n                    <jats:italic>Eucalyptus globulus<\/jats:italic>\n                    and\n                    <jats:italic>Rosmarinus officinalis<\/jats:italic>\n                    EOs (AB1 and AB2; cinnamon EOs from two different suppliers) were active against the fourteen Gram\u2010positive and \u2010negative bacteria strains tested, including some antibiotic\u2010resistant strains. Minimal inhibitory concentrations (MICs) ranged from 0.01% to 3% v\/v with minimal bactericidal concentrations from &lt;0.01% to 6.00% v\/v; (2) a blend of\n                    <jats:italic>Cinnamomum zeylanicum<\/jats:italic>\n                    ,\n                    <jats:italic>Daucus carota, Syzygium aromaticum, Origanum vulgare<\/jats:italic>\n                    EOs was antifungal to the six\n                    <jats:italic>Candida<\/jats:italic>\n                    strains tested, with MICs ranging from 0.01% to 0.05% v\/v with minimal fungicidal concentrations from 0.02% to 0.05% v\/v. Blend AB1 was also effective against H1N1 and HSV1 viruses. With this dual activity, against H1N1 and against\n                    <jats:italic>S.\u00a0aureus<\/jats:italic>\n                    and\n                    <jats:italic>S.\u00a0pneumoniae<\/jats:italic>\n                    notably, AB1 may be interesting to treat influenza and postinfluenza bacterial pneumonia infections. These blends could be very useful in clinical practice to combat common infections including those caused by microorganisms resistant to antimicrobial drugs.\n                  <\/jats:p>","DOI":"10.1002\/mbo3.459","type":"journal-article","created":{"date-parts":[[2017,3,14]],"date-time":"2017-03-14T17:14:42Z","timestamp":1489511682000},"source":"Crossref","is-referenced-by-count":156,"title":["Antibacterial, antifungal, and antiviral effects of three essential oil blends"],"prefix":"10.1002","volume":"6","author":[{"given":"Amandine","family":"Brochot","sequence":"first","affiliation":[{"name":"PiLeJe  Paris Cedex 15 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e8le","family":"Guilbot","sequence":"additional","affiliation":[{"name":"PiLeJe  Paris Cedex 15 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00efla","family":"Haddioui","sequence":"additional","affiliation":[{"name":"Fonderephar  Toulouse Cedex 09 France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Roques","sequence":"additional","affiliation":[{"name":"Fonderephar  Toulouse Cedex 09 France"},{"name":"Laboratoire de G\u00e9nie Chimique UMR 5503 Facult\u00e9 des Sciences Pharmaceutiques Universit\u00e9 Paul Sabatier  Toulouse France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,3,14]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"AFNOR(2015).Norme NF EN 14476 Antiseptiques et d\u00e9sinfectants chimiques \u2010 Essai virucide quantitatif de suspension pour les antiseptiques et d\u00e9sinfectants chimiques utilis\u00e9s en m\u00e9decine humaine."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.2955"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecam\/nep187"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2007.09.106"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules17043989"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12176"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.19.1.50-62.2006"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00284-007-9045-0"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2015.999668"},{"key":"e_1_2_6_11_1","unstructured":"European Medicines Agency (EMA) Evaluation of Medicines for Human Use Committee on herbal medicinal products (HMPC)(2010).Community herbal monograph on Rosmarinus officinalis l. aetheroleum.http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Herbal_-_Community_herbal_monograph\/2011\/01\/WC500101493.pdf. 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