{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T10:47:34Z","timestamp":1782470854224,"version":"3.54.5"},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["MicrobiologyOpen"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      Carbapenem\u2010resistant Gram\u2010negative bacilli (CR\u2010GNB) are an emerging public health threat due to limited treatment options. This retrospective study investigated the epidemiology and resistance patterns of CR\u2010GNB isolated at the National Hospital Center of Nouakchott, Mauritania, between January 2020 and June 2022. Among 565 Gram\u2010negative bacilli isolates, 25 were carbapenem\u2010resistant, corresponding to a prevalence of 4.42%.\n                      <jats:italic>Klebsiella pneumoniae<\/jats:italic>\n                      and\n                      <jats:italic>Escherichia coli<\/jats:italic>\n                      were the most frequently identified species, and most isolates were recovered from urine samples. High resistance rates were observed to beta\u2010lactams and fluoroquinolones, whereas colistin, tigecycline, and amikacin retained good activity. Although the prevalence remains relatively low, continuous surveillance and appropriate infection control and antimicrobial stewardship measures are required to prevent the spread of carbapenem resistance.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/mbo3.70337","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T03:40:50Z","timestamp":1782445250000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Carbapenem\u2010Resistant Gram\u2010Negative Bacilli in Mauritania: A Major Public Health Threat"],"prefix":"10.1002","volume":"15","author":[{"given":"Fatimetou Ahmed","family":"Sid'Ahmed","sequence":"first","affiliation":[{"name":"Laboratories of the Centre Hospitalier National de Nouakchott  Mauritania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4001-9550","authenticated-orcid":false,"given":"Aminetou Mohamed","family":"Abbe","sequence":"additional","affiliation":[{"name":"Faculty of Sciences and Technology University of Nouakchott  Mauritania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7650-7575","authenticated-orcid":false,"given":"Mohamed Lemine","family":"Salem","sequence":"additional","affiliation":[{"name":"Laboratories of the Centre Hospitalier National de Nouakchott  Mauritania"},{"name":"Faculty of Medicine, Pharmacy and Odontostomatology University of Nouakchott  Mauritania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"issue":"3","key":"e_1_2_11_2_1","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.patbio.2014.01.005","article-title":"Actualit\u00e9 De La R\u00e9sistance Aux Antibiotiques Chez Les Bacilles \u00c0 Gram N\u00e9gatif En Alg\u00e9rie","volume":"62","author":"Baba Ahmed\u2010Kazi Tani Z.","year":"2014","journal-title":"Pathologie Biologie"},{"issue":"4","key":"e_1_2_11_3_1","first-page":"S29","article-title":"Carbapenem Resistance of Enterobacteriaceae in Our Institution (2014\u20102016)","volume":"47","author":"Benammar S.","year":"2017","journal-title":"M\u00e9decine Mal Infect"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25061340"},{"issue":"6","key":"e_1_2_11_5_1","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/QCO.0000000000000608","article-title":"Epidemiology of Carbapenem\u2010Resistant Gram\u2010Negative Infections Globally","volume":"32","author":"Brink A. 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