{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:03:27Z","timestamp":1790751807684,"version":"4.1.0"},"reference-count":58,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["MicrobiologyOpen"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Marine ecosystems are becoming important reservoirs for antimicrobial resistance (AMR). However, genomic data on ESBL (Extended\u2010Spectrum Beta\u2010Lactamase)\u2010producing\n                    <jats:italic>Enterobacter<\/jats:italic>\n                    species from marine environments are limited. The widespread\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>\n                      CTX\n                      <jats:italic>\u2010<\/jats:italic>\n                      M\u201015\n                    <\/jats:sub>\n                    gene, usually found in clinical and wastewater settings, has not been reported in marine\n                    <jats:italic>Enterobacter<\/jats:italic>\n                    from Bangladesh. A thermotolerant, lactose\u2010fermenting isolate (LB01) from the Bay of Bengal seawater near Laboni Beach, Cox's Bazar, was isolated and identified as\n                    <jats:italic>Enterobacter kobei<\/jats:italic>\n                    based on &gt;\u200999.4% average nucleotide identity and phylogenetic clustering. Its 4.62\u2009Mb genome (55.05% GC) encoded 4410 genes, including\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>\n                      CTX\n                      <jats:italic>\u2010<\/jats:italic>\n                      M\u201015\n                    <\/jats:sub>\n                    ,\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>\n                      ACT\n                      <jats:italic>\u2010<\/jats:italic>\n                      9\n                    <\/jats:sub>\n                    , and\n                    <jats:italic>qnrS1<\/jats:italic>\n                    , with\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>\n                      CTX\n                      <jats:italic>\u2010<\/jats:italic>\n                      M\u201015\n                    <\/jats:sub>\n                    located next to an ISEc9\u2010like insertion sequence, indicating a mobilizable resistance locus. The genome also contained efflux systems (\n                    <jats:italic>acrAB, mdtABC, oqxAB<\/jats:italic>\n                    ), adhesion and iron uptake genes (\n                    <jats:italic>fim, flh, ent, fep, chu<\/jats:italic>\n                    ), and comprehensive halotolerance modules (\n                    <jats:italic>proVWX, betT, nhaA, kdpABC, mscL\/S<\/jats:italic>\n                    ) consistent with its growth in up to 7% NaCl. This is the first genomic characterization of a marine\n                    <jats:italic>E. kobei<\/jats:italic>\n                    carrying\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>\n                      CTX\n                      <jats:italic>\u2010<\/jats:italic>\n                      M\u201015\n                    <\/jats:sub>\n                    resistant determinant in Bangladesh, showing convergence of resistance, virulence, and halotolerance traits that support persistence in saline, human\u2010impacted environments. The findings broaden the ecological scope of clinically relevant ESBL genes and highlight the importance of coastal ecosystems as overlooked nodes in the global AMR network within a One Health framework.\n                  <\/jats:p>","DOI":"10.1002\/mbo3.70425","type":"journal-article","created":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:39:44Z","timestamp":1790750384000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["First Report of\n                    <i>bla<\/i>\n                    <sub>\n                      CTX\n                      <i>\u2010<\/i>\n                      M\u201015\n                    <\/sub>\n                    in a Marine Thermotolerant\n                    <i>Enterobacter<\/i>\n                    Isolate From Bangladesh: Genomic Insights Into Halotolerance and Antimicrobial Resistance"],"prefix":"10.1002","volume":"15","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-8189-1387","authenticated-orcid":false,"given":"Md. Arifur","family":"Rahman","sequence":"first","affiliation":[{"name":"Department of Microbiology University of Dhaka Dhaka Bangladesh"},{"name":"Department of Microbiology, School of Life Sciences BRAC University Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafid Muntasir Ul","family":"Azam","sequence":"additional","affiliation":[{"name":"Department of Microbiology University of Dhaka Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Sazib","family":"Hossain","sequence":"additional","affiliation":[{"name":"Department of Microbiology Jahangirnagar University Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1915-8727","authenticated-orcid":false,"given":"Samina","family":"Momtaz","sequence":"additional","affiliation":[{"name":"Department of Microbiology University of Dhaka Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9915-3311","authenticated-orcid":false,"given":"Anowara","family":"Begum","sequence":"additional","affiliation":[{"name":"Department of Microbiology University of Dhaka Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8563-3661","authenticated-orcid":false,"given":"Munawar","family":"Sultana","sequence":"additional","affiliation":[{"name":"Department of Microbiology University of Dhaka Dhaka Bangladesh"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac920"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00426"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10643389.2019.1692611"},{"key":"e_1_2_12_5_1","unstructured":"Andrews S. 2010. 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