{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:02:04Z","timestamp":1784037724268,"version":"3.55.0"},"reference-count":4,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,2,22]],"date-time":"2019-02-22T00:00:00Z","timestamp":1550793600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["MicrobiologyOpen"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The worldwide increase in infections caused by extended\u2010spectrum beta\u2010lactamase\u2010 (ESBL) and AmpC\u2010producing Enterobacteriaceae (ESBL\u2010E) is a concern. Surveillance is extensive in Europe, North America, and Asia. Yet, there is no summarizing surveillance in Africa. This study aimed to perform a preliminary investigation on the prevalence of ESBL\u2010E in the northeastern part of Nigeria. However, of the 60 samples collected, we were able to culture 15 <jats:italic>Escherichia coli<\/jats:italic> and 7 <jats:italic>Klebsiella <\/jats:italic>spp. only. In the collection of clinical hospital samples, we found eight of 15 <jats:italic>E.\u00a0coli <\/jats:italic>isolates to be ESBL (53%) and two out of seven <jats:italic>Klebsiella <\/jats:italic>spp. to be ESBL\/AmpC (29%). Due to the limitations of this study, our findings cannot take a broad view on the prevalence of ESBL\u2010E, in Nigeria and other parts of Africa. Yet, to know which genes encode ESBL in Nigeria, and to know exact prevalence of every ESBL gene would be of importance.<\/jats:p>","DOI":"10.1002\/mbo3.816","type":"journal-article","created":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T02:52:38Z","timestamp":1551149558000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["ESBL\u2010production in <i>Escherichia coli <\/i>and <i>Klebsiella pneumoniae <\/i>isolates from Nigeria"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0888-4616","authenticated-orcid":false,"given":"Frederik B.","family":"Hertz","sequence":"first","affiliation":[{"name":"Department of Clinical Microbiology, Hvidovre Hospital University of Copenhagen Hvidovre Denmark"},{"name":"Department of Virus &amp; Microbiological Special Diagnostics Statens Serum Institut Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fillip","family":"Jans\u00e5ker","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Hvidovre Hospital University of Copenhagen Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth O.","family":"Okon","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology, Federal Medical Centre Makurdi Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ibrahim S.","family":"Abdulmumin","sequence":"additional","affiliation":[{"name":"Department of Medical Microbiology Abubakar Tafawa Balewa University Teaching Hospital Bauchi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph O.","family":"Onah","sequence":"additional","affiliation":[{"name":"Clinton Health Access Initiative Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Ladan","sequence":"additional","affiliation":[{"name":"Department of Disease and Immunization National Primary Health Care Development Agency Abuja Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny D.","family":"Knudsen","sequence":"additional","affiliation":[{"name":"Department of Clinical Microbiology, Hvidovre Hospital University of Copenhagen Hvidovre Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,22]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.4314\/ajcem.v18i1.3"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/23744235.2015.1103895"},{"key":"e_1_2_8_4_1","unstructured":"Pedersen K.(2016).Danmap 2016."},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.3402\/iee.v4.20342"}],"container-title":["MicrobiologyOpen"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmbo3.816","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mbo3.816","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mbo3.816","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mbo3.816","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T00:18:23Z","timestamp":1694218703000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mbo3.816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,22]]},"references-count":4,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1002\/mbo3.816"],"URL":"https:\/\/doi.org\/10.1002\/mbo3.816","archive":["Portico"],"relation":{},"ISSN":["2045-8827","2045-8827"],"issn-type":[{"value":"2045-8827","type":"print"},{"value":"2045-8827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,22]]},"assertion":[{"value":"2018-12-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-01-22","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-02-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00816"}}