{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:57:40Z","timestamp":1790524660003,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2019,5,22]],"date-time":"2019-05-22T00:00:00Z","timestamp":1558483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003443","name":"Ministry of Education and Science of the Russian Federation","doi-asserted-by":"publisher","award":["6.2379.2017\/PCh"],"award-info":[{"award-number":["6.2379.2017\/PCh"]}],"id":[{"id":"10.13039\/501100003443","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"Russian Foundation for Basic Research","doi-asserted-by":"publisher","award":["17-04-00787 A"],"award-info":[{"award-number":["17-04-00787 A"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["MicrobiologyOpen"],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    In this study, we compared the expression of\n                    <jats:italic>CYP153<\/jats:italic>\n                    ,\n                    <jats:italic>sodA<\/jats:italic>\n                    ,\n                    <jats:italic>sodC,<\/jats:italic>\n                    and\n                    <jats:italic>recA<\/jats:italic>\n                    genes and ROS generation in hydrocarbon\u2010degrading\n                    <jats:italic>Rhodococcus erythropolis<\/jats:italic>\n                    in the presence of cyclohexane, naphthalene, and diesel fuel. The expression of cytochrome P450,\n                    <jats:italic>sodA<\/jats:italic>\n                    (encoding Fe\/Mn superoxide dismutase),\n                    <jats:italic>recA,<\/jats:italic>\n                    and superoxide anion radical generation rate increased after the addition of all studied hydrocarbons. The peak of\n                    <jats:italic>CYP153<\/jats:italic>\n                    ,\n                    <jats:italic>sodA,<\/jats:italic>\n                    and\n                    <jats:italic>recA<\/jats:italic>\n                    gene expression was registered in the presence of naphthalene. The same substrate upregulated the Cu\/Zn superoxide dismutase gene,\n                    <jats:italic>sodC<\/jats:italic>\n                    . Cyclohexane generated the highest level of superoxide anion radical production. Hydrogen peroxide accumulated in the medium enriched with diesel fuel. Taken together, hydrocarbon biotransformation leads to oxidative stress and upregulation of antioxidant enzymes and\n                    <jats:italic>CYP153<\/jats:italic>\n                    genes, and increases DNA reparation levels in\n                    <jats:italic>R. erythropolis<\/jats:italic>\n                    cells.\n                  <\/jats:p>","DOI":"10.1002\/mbo3.855","type":"journal-article","created":{"date-parts":[[2019,5,23]],"date-time":"2019-05-23T10:23:55Z","timestamp":1558607035000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":30,"title":["Cyclohexane, naphthalene, and diesel fuel increase oxidative stress,\n                    <i>CYP153<\/i>\n                    ,\n                    <i>sodA,<\/i>\n                    and\n                    <i>recA<\/i>\n                    gene expression in\n                    <i>Rhodococcus erythropolis<\/i>"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0864-1473","authenticated-orcid":false,"given":"Ivan","family":"Sazykin","sequence":"first","affiliation":[{"name":"Southern Federal University Rostov\u2010on\u2010Don Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0629-3874","authenticated-orcid":false,"given":"Maksim","family":"Makarenko","sequence":"additional","affiliation":[{"name":"Southern Federal University Rostov\u2010on\u2010Don Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0781-2207","authenticated-orcid":false,"given":"Ludmila","family":"Khmelevtsova","sequence":"additional","affiliation":[{"name":"Southern Federal University Rostov\u2010on\u2010Don Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2940-803X","authenticated-orcid":false,"given":"Ekaterina","family":"Seliverstova","sequence":"additional","affiliation":[{"name":"Southern Federal University Rostov\u2010on\u2010Don Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1166-0728","authenticated-orcid":false,"given":"Alexander","family":"Rakin","sequence":"additional","affiliation":[{"name":"Institute for Bacterial Infections and Zoonoses Friedrich\u2010Loeffler\u2010Institut, Federal Research Institute for Animal Health Jena Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6974-3361","authenticated-orcid":false,"given":"Marina","family":"Sazykina","sequence":"additional","affiliation":[{"name":"Southern Federal University Rostov\u2010on\u2010Don Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,5,22]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/1462-2920.14459"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01512-18"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.06.119"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-15-1120"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2008.112797"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.83"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02773-17"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.695320"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00286-06"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3109\/10408449509089886"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0003683812060051"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx0002583"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/jb.177.22.6330-6337.1995"},{"issue":"4","key":"e_1_2_11_15_1","first-page":"174","article-title":"The role of cytochrome p\u2010450\u2010dependent monooxygenase enzyme systems of bacteria of the genus Pseudomonas in xenobiotics biotransformation and biodegradation","volume":"1","author":"Ignatovets O. S.","year":"2009","journal-title":"Proceedings of Belarusian State Technological University. Chemistry, Organic Technology and Biotechnology"},{"key":"e_1_2_11_16_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2007\/008896-0"},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-9-60"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0003683817040093"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.69.2421"},{"issue":"9","key":"e_1_2_11_20_1","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1128\/JB.181.9.2719-2725.1999","article-title":"Benzene\u2010induced uncoupling of naphthalene dioxygenase activity and enzyme inactivation by production of hydrogen peroxide","volume":"181","author":"Lee K.","year":"1999","journal-title":"Journal of Bacteriology"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.2166\/wst.2014.470"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ecoenv.2015.02.007"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.2001.5449"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1003764"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.enzmictec.2011.04.021"},{"issue":"3","key":"e_1_2_11_26_1","first-page":"71","article-title":"An improvement of the 2\u02c6(\u2013delta delta CT) method for quantitative real\u2010time polymerase chain reaction data analysis","volume":"3","author":"Rao X.","year":"2013","journal-title":"Biostatistics, Bioinformatics and Biomathematics"},{"key":"e_1_2_11_27_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10482-015-0524-1"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-2920.2009.01948.x"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13213-015-1188-9"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00203-018-1516-0"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.2133\/dmpk.21.257"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-017-8537-0"},{"key":"e_1_2_11_33_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2672.2002.01728.x"},{"key":"e_1_2_11_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.femsle.2004.10.013"},{"key":"e_1_2_11_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-006-0748-0"},{"key":"e_1_2_11_36_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.72.1.59-65.2006"},{"key":"e_1_2_11_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2229-10-59"},{"key":"e_1_2_11_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089302"}],"container-title":["MicrobiologyOpen"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fmbo3.855","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mbo3.855","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mbo3.855","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mbo3.855","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,8]],"date-time":"2023-09-08T20:16:09Z","timestamp":1694204169000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mbo3.855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,5,22]]},"references-count":37,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1002\/mbo3.855"],"URL":"https:\/\/doi.org\/10.1002\/mbo3.855","archive":["Portico"],"relation":{},"ISSN":["2045-8827","2045-8827"],"issn-type":[{"value":"2045-8827","type":"print"},{"value":"2045-8827","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,5,22]]},"assertion":[{"value":"2018-12-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-22","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e00855"}}