{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T00:24:57Z","timestamp":1772843097761,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T00:00:00Z","timestamp":1600300800000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91859120"],"award-info":[{"award-number":["91859120"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MedComm"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Axillary reverse mapping (ARM) is a technique to identify arm lymphatic drainage during axillary lymph node dissection (ALND). This study compared the feasibility of ARM using indocyanine green (ICG) or methylene blue (MB), and accessed the oncologic safety of the procedure. Overall, 158 patients qualified for ALND were enrolled. The characteristics of ARM\u2010identified nodes were recorded with ICG (n\u00a0=\u00a078) or MB (n\u00a0=\u00a080) visualization. Fine\u2010needle aspiration cytology (FNAC) of the nodes were performed and validated by histologic analysis. The nodal identification rate in the ICG group significantly surpassed that of the MB group (87.2%\u00a0vs 52.5%, <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.05) with fewer complications. Note that 10.9% of the patients had metastatic involvement of the ARM\u2010identified nodes. Also 80% of the positive nodes were found in areas B and D, while the ARM\u2010identified nodes mainly located in area A. All the 51 nodes diagnosed as negative of malignancy by FNAC were free of metastasis. Nodal metastasis was significantly correlated with extensive nodel involvement, advanced disease, and the characteristics of identified nodes. In conclusion, ICG appears superior to MB for ARM nodes identification. FNAC, together with the features of primary tumors and ARM nodes, can delineate which nodes could be preserved during ALND.<\/jats:p>","DOI":"10.1002\/mco2.31","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T08:45:55Z","timestamp":1600332355000},"page":"211-218","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of indocyanine green and methylene blue use for axillary reverse mapping during axillary lymph node dissection"],"prefix":"10.1002","volume":"1","author":[{"given":"Jun\u2010Dong","family":"Wu","sequence":"first","affiliation":[{"name":"The Breast Center Cancer Hospital of Shantou University Medical College  Shantou Guangdong China"},{"name":"Guangdong Provincial Key Laboratory for Breast Cancer Diagnosis and Treatment Cancer Hospital of Shantou University Medical College  Shantou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zun","family":"Wang","sequence":"additional","affiliation":[{"name":"ChangJiang Scholar's Laboratory Shantou University Medical College (SUMC)  Shantou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan\u2010Cheng","family":"Zeng","sequence":"additional","affiliation":[{"name":"The Breast Center Cancer Hospital of Shantou University Medical College  Shantou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li\u2010Fang","family":"He","sequence":"additional","affiliation":[{"name":"The Breast Center Cancer Hospital of Shantou University Medical College  Shantou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong\u2010Qu","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Breast Center Cancer Hospital of Shantou University Medical College  Shantou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guang\u2010Sheng","family":"Huang","sequence":"additional","affiliation":[{"name":"The Breast Center Cancer Hospital of Shantou University Medical College  Shantou Guangdong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fan","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Central Laboratory Cancer Hospital of Shantou University Medical College  Shantou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao\u2010Long","family":"Wei","sequence":"additional","affiliation":[{"name":"Department of Pathology Cancer Hospital of Shantou University Medical College  Shantou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen\u2010He","family":"Huang","sequence":"additional","affiliation":[{"name":"Cancer Center &amp; 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