{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:17:07Z","timestamp":1791605827549,"version":"4.3.4"},"reference-count":414,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T00:00:00Z","timestamp":1758153600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82472993"],"award-info":[{"award-number":["82472993"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971361"],"award-info":[{"award-number":["81971361"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173188"],"award-info":[{"award-number":["82173188"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MedComm"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Neutrophils, constituting a predominant subset of innate immune cells in mammalian systems, play pivotal roles in pathogenic clearance and homeostatic maintenance. In the progressive development of cancer, neutrophils exert dual roles in both anticancer and procancer processes through their heterogeneity. In recent years, research into the role of neutrophils in cancer and various nontumor diseases has been continuously deepening. However, current research in this area remains incomplete. This review comprehensively summarizes the tissue homing dynamics, lifespan regulation, and physiological functions of neutrophils, starting from their development and heterogeneity. Furthermore, we delineate the dual regulatory functions of neutrophils in carcinogenesis, encompassing both tumor\u2010suppressive mechanisms and protumor mechanisms. This section further synthesizes recent advancements in neutrophil\u2010targeted therapeutic platforms and biomimetic delivery systems, while critically evaluating persistent methodological and translational challenges in clinical applications. In addition, we systematically analyze the role of neutrophils in non\u2010neoplastic diseases and list several typical diseases, including infectious diseases. Finally, we also discuss current controversies and research perspectives on neutrophils. It is hoped that this review will deepen insights into the role of neutrophils in homeostasis and disease, while exploring their potential in disease treatment.<\/jats:p>","DOI":"10.1002\/mco2.70390","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T06:56:58Z","timestamp":1758265018000},"source":"Crossref","is-referenced-by-count":13,"title":["Role of Neutrophils in Homeostasis and Diseases"],"prefix":"10.1002","volume":"6","author":[{"given":"Xingyu","family":"Chang","sequence":"first","affiliation":[{"name":"Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases Obstetrics &amp; Gynecology Hospital of Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulin","family":"Liu","sequence":"additional","affiliation":[{"name":"Cancer Center Union Hospital Tongji Medical College Huazhong University of Science and Technology  Wuhan China"},{"name":"Institute of Radiation Oncology Union Hospital Tongji Medical College Huazhong University of Science and Technology  Wuhan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjun","family":"Qiu","sequence":"additional","affiliation":[{"name":"Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases Obstetrics &amp; Gynecology Hospital of Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keqin","family":"Hua","sequence":"additional","affiliation":[{"name":"Shanghai Key Lab of Reproduction and Development Shanghai Key Lab of Female Reproductive Endocrine Related Diseases Obstetrics &amp; Gynecology Hospital of Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,9,18]]},"reference":[{"key":"e_1_2_14_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00571-6"},{"key":"e_1_2_14_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12458"},{"key":"e_1_2_14_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-024-02006-5"},{"key":"e_1_2_14_5_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adf6493"},{"key":"e_1_2_14_6_1","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2022.0426"},{"key":"e_1_2_14_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfad266"},{"key":"e_1_2_14_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-02049-y"},{"key":"e_1_2_14_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.11.011"},{"key":"e_1_2_14_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1341390"},{"key":"e_1_2_14_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-023-01452-x"},{"key":"e_1_2_14_12_1","doi-asserted-by":"publisher","DOI":"10.1042\/EBC20220245"},{"key":"e_1_2_14_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.70063"},{"key":"e_1_2_14_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-0736-z"},{"key":"e_1_2_14_15_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI57990"},{"key":"e_1_2_14_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0141-8"},{"key":"e_1_2_14_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2016.03.005"},{"key":"e_1_2_14_18_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aah4966"},{"key":"e_1_2_14_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2023.05.010"},{"key":"e_1_2_14_20_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-024-02096-7"},{"key":"e_1_2_14_21_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-121808-102144"},{"key":"e_1_2_14_22_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0060301"},{"key":"e_1_2_14_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-024-00727-x"},{"key":"e_1_2_14_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00785-2"},{"key":"e_1_2_14_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature15367"},{"key":"e_1_2_14_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-22973-9"},{"key":"e_1_2_14_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2019.04.012"},{"key":"e_1_2_14_28_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20130056"},{"key":"e_1_2_14_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2194"},{"key":"e_1_2_14_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.12.039"},{"key":"e_1_2_14_31_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02456"},{"key":"e_1_2_14_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3801-8_13"},{"key":"e_1_2_14_33_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000188336.94090.14"},{"key":"e_1_2_14_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.05.091"},{"key":"e_1_2_14_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/039463201102400314"},{"key":"e_1_2_14_36_1","doi-asserted-by":"publisher","DOI":"10.1097\/SHK.0b013e318173ef9c"},{"key":"e_1_2_14_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e318274647d"},{"key":"e_1_2_14_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12448"},{"key":"e_1_2_14_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003993"},{"key":"e_1_2_14_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2013.02.007"},{"key":"e_1_2_14_41_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e328354b43f"},{"key":"e_1_2_14_42_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.26123"},{"key":"e_1_2_14_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.41395"},{"key":"e_1_2_14_44_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0902199"},{"key":"e_1_2_14_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4027"},{"key":"e_1_2_14_46_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100450"},{"key":"e_1_2_14_47_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100123"},{"key":"e_1_2_14_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3399"},{"key":"e_1_2_14_49_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-07-343566"},{"key":"e_1_2_14_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1015855107"},{"key":"e_1_2_14_51_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1002459"},{"key":"e_1_2_14_52_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02712"},{"key":"e_1_2_14_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13464"},{"key":"e_1_2_14_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.603230"},{"key":"e_1_2_14_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3660"},{"key":"e_1_2_14_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15092626"},{"key":"e_1_2_14_57_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-022-04585-3"},{"key":"e_1_2_14_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1283"},{"issue":"16","key":"e_1_2_14_59_1","first-page":"1163","article-title":"Neutrophils in Cancer: Dual Roles Through Intercellular Interactions","volume":"43","author":"Yu X.","year":"2024","journal-title":"Oncogene"},{"key":"e_1_2_14_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2017.11.004"},{"key":"e_1_2_14_61_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-3614"},{"key":"e_1_2_14_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.05.082"},{"key":"e_1_2_14_63_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-01-259028"},{"key":"e_1_2_14_64_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-03-700336"},{"key":"e_1_2_14_65_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-023-01843-6"},{"key":"e_1_2_14_66_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.631821"},{"key":"e_1_2_14_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.23"},{"key":"e_1_2_14_68_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009601220552"},{"key":"e_1_2_14_69_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1998.00741.x"},{"key":"e_1_2_14_70_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.69.3.467"},{"key":"e_1_2_14_71_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V80.8.2012.2012"},{"key":"e_1_2_14_72_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-1060-2_8"},{"key":"e_1_2_14_73_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V81.11.2866.2866"},{"key":"e_1_2_14_74_1","doi-asserted-by":"publisher","DOI":"10.1093\/burnst\/tkz001"},{"key":"e_1_2_14_75_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40169-017-0154-5"},{"issue":"1","key":"e_1_2_14_76_1","first-page":"223","article-title":"Neutrophil Fate in Experimental Glomerular Capillary Injury in the Rat. Emigration Exceeds in Situ Clearance by Apoptosis","volume":"150","author":"Hughes J.","year":"1997","journal-title":"American Journal of Pathology"},{"key":"e_1_2_14_77_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12950-022-00320-z"},{"key":"e_1_2_14_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2016.49"},{"key":"e_1_2_14_79_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V64.1.147.147"},{"key":"e_1_2_14_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13082390"},{"key":"e_1_2_14_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2022.08.010"},{"key":"e_1_2_14_82_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20122220"},{"key":"e_1_2_14_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12440"},{"key":"e_1_2_14_84_1","first-page":"28","article-title":"Targeting NETosis: Nature's Alarm System in Cancer Progression","volume":"7","author":"Liang Y.","year":"2024","journal-title":"Cancer Drug Resist"},{"key":"e_1_2_14_85_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0810457"},{"key":"e_1_2_14_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.06.044"},{"key":"e_1_2_14_87_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0607338"},{"key":"e_1_2_14_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-017-1510-z"},{"key":"e_1_2_14_89_1","doi-asserted-by":"publisher","DOI":"10.1039\/b904701h"},{"key":"e_1_2_14_90_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1092385"},{"key":"e_1_2_14_91_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1296783"},{"key":"e_1_2_14_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.162"},{"key":"e_1_2_14_93_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00062.2021"},{"key":"e_1_2_14_94_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20200652"},{"key":"e_1_2_14_95_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1565"},{"key":"e_1_2_14_96_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005743107"},{"key":"e_1_2_14_97_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-05-283564"},{"key":"e_1_2_14_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri1785"},{"key":"e_1_2_14_99_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00652.2023"},{"key":"e_1_2_14_100_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.3HI1014-493R"},{"key":"e_1_2_14_101_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00034.x"},{"key":"e_1_2_14_102_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0706438104"},{"key":"e_1_2_14_103_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00022.2006"},{"key":"e_1_2_14_104_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01166-6"},{"key":"e_1_2_14_105_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00395-019-0746-x"},{"key":"e_1_2_14_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10903-9"},{"key":"e_1_2_14_107_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0240-6"},{"key":"e_1_2_14_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.04.018"},{"key":"e_1_2_14_109_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2085-17.2017"},{"key":"e_1_2_14_110_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI110647"},{"key":"e_1_2_14_111_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.13158"},{"key":"e_1_2_14_112_1","doi-asserted-by":"publisher","DOI":"10.1093\/jleuko\/qiae057"},{"key":"e_1_2_14_113_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242417583"},{"issue":"10","key":"e_1_2_14_114_1","first-page":"1663","article-title":"Metabolic Reprogramming of Innate Immune Cells as a Possible Source of New Therapeutic Approaches in","volume":"11","author":"Mohammadnezhad L.","year":"2022","journal-title":"Autoimmunity Cells"},{"key":"e_1_2_14_115_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI84426"},{"key":"e_1_2_14_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/sigtrans.2017.23"},{"key":"e_1_2_14_117_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00085"},{"key":"e_1_2_14_118_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00108.2013"},{"key":"e_1_2_14_119_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-018-1710-1"},{"key":"e_1_2_14_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2023.166820"},{"key":"e_1_2_14_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.103"},{"key":"e_1_2_14_122_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI111442"},{"key":"e_1_2_14_123_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.995993"},{"key":"e_1_2_14_124_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.03076"},{"key":"e_1_2_14_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.07.012"},{"key":"e_1_2_14_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-023-01738-0"},{"key":"e_1_2_14_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2020.11.016"},{"key":"e_1_2_14_128_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.1109"},{"key":"e_1_2_14_129_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.954"},{"key":"e_1_2_14_130_1","doi-asserted-by":"publisher","DOI":"10.4110\/in.2020.20.e46"},{"key":"e_1_2_14_131_1","doi-asserted-by":"publisher","DOI":"10.33594\/000000245"},{"key":"e_1_2_14_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2021.08.027"},{"key":"e_1_2_14_133_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V47.3.431.431"},{"issue":"5","key":"e_1_2_14_134_1","first-page":"947","article-title":"Cytoplasmic Lipid Bodies of human Neutrophilic Leukocytes","volume":"135","author":"Weller P. F.","year":"1989","journal-title":"American Journal of Pathology"},{"key":"e_1_2_14_135_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2249.1997.d01-888.x"},{"key":"e_1_2_14_136_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-0281-y"},{"key":"e_1_2_14_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2009.06.017"},{"key":"e_1_2_14_138_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1599"},{"key":"e_1_2_14_139_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-024-02004-z"},{"key":"e_1_2_14_140_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/8078646"},{"key":"e_1_2_14_141_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.325"},{"key":"e_1_2_14_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3024"},{"key":"e_1_2_14_143_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-1808"},{"key":"e_1_2_14_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.04.016"},{"key":"e_1_2_14_145_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.29297"},{"key":"e_1_2_14_146_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI130952"},{"key":"e_1_2_14_147_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2017.1373234"},{"key":"e_1_2_14_148_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241210265"},{"key":"e_1_2_14_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.03.007"},{"key":"e_1_2_14_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.111171"},{"key":"e_1_2_14_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.02.032"},{"key":"e_1_2_14_152_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812347106"},{"key":"e_1_2_14_153_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-021-01187-y"},{"key":"e_1_2_14_154_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-0281-y"},{"key":"e_1_2_14_155_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-1591"},{"key":"e_1_2_14_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2022.101595"},{"key":"e_1_2_14_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-7613(00)80504-X"},{"key":"e_1_2_14_158_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgl003"},{"key":"e_1_2_14_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2004.08.031"},{"key":"e_1_2_14_160_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-1734"},{"key":"e_1_2_14_161_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2005.04.007"},{"key":"e_1_2_14_162_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22020843"},{"key":"e_1_2_14_163_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.01.007"},{"key":"e_1_2_14_164_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-21-1059"},{"key":"e_1_2_14_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2025.217466"},{"key":"e_1_2_14_166_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20040624"},{"key":"e_1_2_14_167_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-24-1056"},{"key":"e_1_2_14_168_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-326070"},{"key":"e_1_2_14_169_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mol.0000226119.20307.2b"},{"key":"e_1_2_14_170_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.add5204"},{"key":"e_1_2_14_171_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18125-0"},{"key":"e_1_2_14_172_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-20-0839"},{"key":"e_1_2_14_173_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-012-1294-5"},{"key":"e_1_2_14_174_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07505-2"},{"key":"e_1_2_14_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2024.08.019"},{"key":"e_1_2_14_176_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-313075"},{"key":"e_1_2_14_177_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.03.001"},{"key":"e_1_2_14_178_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-017-0022-x"},{"key":"e_1_2_14_179_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-051013-052304"},{"key":"e_1_2_14_180_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20201803"},{"key":"e_1_2_14_181_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.2.977"},{"key":"e_1_2_14_182_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10456-011-9207-3"},{"key":"e_1_2_14_183_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-15-1157"},{"key":"e_1_2_14_184_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05443-0"},{"key":"e_1_2_14_185_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202307870"},{"key":"e_1_2_14_186_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1118-2"},{"key":"e_1_2_14_187_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-023-00493-6"},{"key":"e_1_2_14_188_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature04186"},{"key":"e_1_2_14_189_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6687474"},{"key":"e_1_2_14_190_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2023.02.001"},{"key":"e_1_2_14_191_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29444"},{"key":"e_1_2_14_192_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature16140"},{"key":"e_1_2_14_193_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2016.217"},{"key":"e_1_2_14_194_1","doi-asserted-by":"publisher","DOI":"10.1038\/35065016"},{"key":"e_1_2_14_195_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M300351200"},{"key":"e_1_2_14_196_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20733-9"},{"key":"e_1_2_14_197_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20181170"},{"key":"e_1_2_14_198_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.134.12.1325"},{"key":"e_1_2_14_199_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-1591"},{"key":"e_1_2_14_200_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.30635"},{"key":"e_1_2_14_201_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.11.037"},{"key":"e_1_2_14_202_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-019-0836-0"},{"key":"e_1_2_14_203_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.44215"},{"key":"e_1_2_14_204_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aag1711"},{"key":"e_1_2_14_205_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aal5081"},{"key":"e_1_2_14_206_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0266-5"},{"key":"e_1_2_14_207_1","doi-asserted-by":"publisher","DOI":"10.1002\/cac2.12613"},{"key":"e_1_2_14_208_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2024.104457"},{"key":"e_1_2_14_209_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2024.217417"},{"key":"e_1_2_14_210_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1204833"},{"key":"e_1_2_14_211_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2015.10.040"},{"key":"e_1_2_14_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2010.02.019"},{"key":"e_1_2_14_213_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2214963"},{"key":"e_1_2_14_214_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-41095-y"},{"key":"e_1_2_14_215_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14163846"},{"key":"e_1_2_14_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2015.07.027"},{"key":"e_1_2_14_217_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2021.03.027"},{"key":"e_1_2_14_218_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202105631"},{"key":"e_1_2_14_219_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-23086-z"},{"key":"e_1_2_14_220_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.07.032"},{"key":"e_1_2_14_221_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.785222"},{"key":"e_1_2_14_222_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2023.03.008"},{"key":"e_1_2_14_223_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2024.03.007"},{"key":"e_1_2_14_224_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1613187113"},{"key":"e_1_2_14_225_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1901562116"},{"key":"e_1_2_14_226_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2400607"},{"key":"e_1_2_14_227_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI175031"},{"key":"e_1_2_14_228_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI178344"},{"key":"e_1_2_14_229_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-017-0707-7"},{"key":"e_1_2_14_230_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pathol.2024.03.003"},{"key":"e_1_2_14_231_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.100"},{"key":"e_1_2_14_232_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1234142"},{"key":"e_1_2_14_233_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abq6221"},{"key":"e_1_2_14_234_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191231"},{"key":"e_1_2_14_235_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-023-00463-y"},{"key":"e_1_2_14_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.117474"},{"key":"e_1_2_14_237_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-04-713206"},{"key":"e_1_2_14_238_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2022.188762"},{"key":"e_1_2_14_239_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-326259"},{"key":"e_1_2_14_240_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsos.210705"},{"key":"e_1_2_14_241_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105010"},{"key":"e_1_2_14_242_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-024-06704-y"},{"key":"e_1_2_14_243_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2213180"},{"key":"e_1_2_14_244_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-024-02326-3"},{"key":"e_1_2_14_245_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcyt.2017.08.012"},{"key":"e_1_2_14_246_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.13196"},{"key":"e_1_2_14_247_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-024-01130-4"},{"key":"e_1_2_14_248_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.4c00452"},{"key":"e_1_2_14_249_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2023-008662"},{"key":"e_1_2_14_250_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2024.06.029"},{"key":"e_1_2_14_251_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2023.216260"},{"key":"e_1_2_14_252_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2023.2261242"},{"key":"e_1_2_14_253_1","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0208125"},{"key":"e_1_2_14_254_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310318"},{"key":"e_1_2_14_255_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-021-01355-1"},{"key":"e_1_2_14_256_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00605"},{"issue":"15","key":"e_1_2_14_257_1","first-page":"3200","article-title":"Antisense Oligonucleotides Specific for Transforming Growth Factor beta2 Inhibit the Growth of Malignant Mesothelioma both in Vitro and in Vivo","volume":"57","author":"Marzo A. L.","year":"1997","journal-title":"Cancer Research"},{"key":"e_1_2_14_258_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232415827"},{"key":"e_1_2_14_259_1","doi-asserted-by":"publisher","DOI":"10.7150\/jca.38179"},{"key":"e_1_2_14_260_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1201654"},{"issue":"7","key":"e_1_2_14_261_1","first-page":"2165","article-title":"Phase I Study of the Syk Inhibitor sovleplenib in Relapsed or Refractory Mature B\u2010cell Tumors","volume":"109","author":"Song Y.","year":"2024","journal-title":"Haematologica"},{"key":"e_1_2_14_262_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmoop.2024.103486"},{"key":"e_1_2_14_263_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(24)00139-X"},{"key":"e_1_2_14_264_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.07.016"},{"key":"e_1_2_14_265_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000365"},{"key":"e_1_2_14_266_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2017.09.012"},{"key":"e_1_2_14_267_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107556"},{"key":"e_1_2_14_268_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12527"},{"key":"e_1_2_14_269_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14143366"},{"key":"e_1_2_14_270_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2021-150606"},{"key":"e_1_2_14_271_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-0458-4"},{"key":"e_1_2_14_272_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clcc.2022.11.002"},{"issue":"16","key":"e_1_2_14_273_1","article-title":"Phase 1 Trial Evaluating TTI\u2010101, a First\u2010in\u2010class, Orally Bioavailable, Small Molecule, Inhibitor of STAT3, in Patients With Advanced Solid Tumors","volume":"41","author":"Tsimberidou A. M.","year":"2023","journal-title":"Journal Of Clinical Oncology"},{"key":"e_1_2_14_274_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2021-055718"},{"key":"e_1_2_14_275_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2015.05.010"},{"key":"e_1_2_14_276_1","doi-asserted-by":"publisher","DOI":"10.2337\/db14-0443"},{"key":"e_1_2_14_277_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12876"},{"key":"e_1_2_14_278_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2023.41.4_suppl.TPS631"},{"key":"e_1_2_14_279_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-21-2517"},{"key":"e_1_2_14_280_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34750"},{"key":"e_1_2_14_281_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi100363t"},{"key":"e_1_2_14_282_1","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1735"},{"key":"e_1_2_14_283_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.16555"},{"key":"e_1_2_14_284_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-21-4045"},{"key":"e_1_2_14_285_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-022-04550-w"},{"key":"e_1_2_14_286_1","doi-asserted-by":"publisher","DOI":"10.2165\/00063030-200519030-00001"},{"key":"e_1_2_14_287_1","doi-asserted-by":"publisher","DOI":"10.1002\/1878-0261.12787"},{"key":"e_1_2_14_288_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-1226"},{"key":"e_1_2_14_289_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.128008"},{"key":"e_1_2_14_290_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201700627"},{"key":"e_1_2_14_291_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-2675-x"},{"key":"e_1_2_14_292_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119952"},{"key":"e_1_2_14_293_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201706245"},{"key":"e_1_2_14_294_1","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201804191"},{"key":"e_1_2_14_295_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.04.004"},{"key":"e_1_2_14_296_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature14282"},{"key":"e_1_2_14_297_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120784"},{"key":"e_1_2_14_298_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.04.013"},{"key":"e_1_2_14_299_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c09318"},{"key":"e_1_2_14_300_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c11280"},{"key":"e_1_2_14_301_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.111128"},{"key":"e_1_2_14_302_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI164918"},{"key":"e_1_2_14_303_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-022-01161-w"},{"key":"e_1_2_14_304_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellimm.2019.01.003"},{"key":"e_1_2_14_305_1","article-title":"Real\u2010Time Measurement of the Mitochondrial Bioenergetic Profile of Neutrophils","volume":"196","author":"Pulikkot S.","year":"2023","journal-title":"Journal of visualized experiments: JoVE"},{"key":"e_1_2_14_306_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1083072"},{"key":"e_1_2_14_307_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abb1069"},{"key":"e_1_2_14_308_1","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202400373"},{"key":"e_1_2_14_309_1","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2019.0372"},{"key":"e_1_2_14_310_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0033-6"},{"key":"e_1_2_14_311_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-023-01490-5"},{"key":"e_1_2_14_312_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11020192"},{"key":"e_1_2_14_313_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2019.09.036"},{"key":"e_1_2_14_314_1","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.1170"},{"key":"e_1_2_14_315_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1144229"},{"key":"e_1_2_14_316_1","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.110.207522"},{"key":"e_1_2_14_317_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.653228"},{"key":"e_1_2_14_318_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-020-00906-z"},{"key":"e_1_2_14_319_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-0901-9"},{"key":"e_1_2_14_320_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00536-9"},{"key":"e_1_2_14_321_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2022.2099206"},{"key":"e_1_2_14_322_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007008"},{"key":"e_1_2_14_323_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-017-0629-x"},{"key":"e_1_2_14_324_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-017-0639-8"},{"key":"e_1_2_14_325_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202250010"},{"key":"e_1_2_14_326_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI141374"},{"key":"e_1_2_14_327_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3782"},{"key":"e_1_2_14_328_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-018-0039-z"},{"key":"e_1_2_14_329_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00787-0"},{"key":"e_1_2_14_330_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000912"},{"key":"e_1_2_14_331_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(24)00398-2"},{"key":"e_1_2_14_332_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.13161"},{"key":"e_1_2_14_333_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-00993-3"},{"key":"e_1_2_14_334_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.924766"},{"key":"e_1_2_14_335_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2018-214620"},{"key":"e_1_2_14_336_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20151876"},{"key":"e_1_2_14_337_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202388"},{"key":"e_1_2_14_338_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13901"},{"key":"e_1_2_14_339_1","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2013-204837"},{"key":"e_1_2_14_340_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-023-00797-8"},{"key":"e_1_2_14_341_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.38703"},{"key":"e_1_2_14_342_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2019097118"},{"key":"e_1_2_14_343_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01525-8"},{"key":"e_1_2_14_344_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000001006"},{"key":"e_1_2_14_345_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2016.00485"},{"key":"e_1_2_14_346_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd2688"},{"key":"e_1_2_14_347_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3005580"},{"key":"e_1_2_14_348_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar4093"},{"key":"e_1_2_14_349_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.109843"},{"key":"e_1_2_14_350_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.139388"},{"key":"e_1_2_14_351_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-025-09044-3"},{"key":"e_1_2_14_352_1","doi-asserted-by":"publisher","DOI":"10.1002\/bies.202100119"},{"key":"e_1_2_14_353_1","doi-asserted-by":"publisher","DOI":"10.1136\/rmdopen-2023-003847"},{"key":"e_1_2_14_354_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-015-0932-8"},{"key":"e_1_2_14_355_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1438272"},{"key":"e_1_2_14_356_1","doi-asserted-by":"publisher","DOI":"10.5483\/BMBRep.2021.54.4.205"},{"key":"e_1_2_14_357_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.965169"},{"key":"e_1_2_14_358_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2023.06.005"},{"key":"e_1_2_14_359_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32205-4"},{"issue":"1","key":"e_1_2_14_360_1","first-page":"266","article-title":"Cellular Transcriptional Alterations of Peripheral Blood in Alzheimer's Disease","volume":"20","author":"Song L.","year":"2022","journal-title":"BMC Medicine [Electronic Resource]"},{"key":"e_1_2_14_361_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-022-01347-2"},{"key":"e_1_2_14_362_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.00211"},{"key":"e_1_2_14_363_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1200409"},{"key":"e_1_2_14_364_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2009.07.012"},{"key":"e_1_2_14_365_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12979-024-00445-0"},{"key":"e_1_2_14_366_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbih.2023.100688"},{"key":"e_1_2_14_367_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3913"},{"key":"e_1_2_14_368_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0b013e3282efed9e"},{"key":"e_1_2_14_369_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.369942"},{"key":"e_1_2_14_370_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)70016-5"},{"key":"e_1_2_14_371_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.16159"},{"key":"e_1_2_14_372_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1123149"},{"key":"e_1_2_14_373_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-230411"},{"key":"e_1_2_14_374_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00218-X"},{"key":"e_1_2_14_375_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00247"},{"key":"e_1_2_14_376_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00684-6"},{"key":"e_1_2_14_377_1","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-223241"},{"key":"e_1_2_14_378_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2022-330394"},{"key":"e_1_2_14_379_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-025-00909-0"},{"key":"e_1_2_14_380_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-021-00271-x"},{"key":"e_1_2_14_381_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-021-00088-6"},{"key":"e_1_2_14_382_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-024-00738-4"},{"key":"e_1_2_14_383_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-017-0010-8"},{"key":"e_1_2_14_384_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0039132"},{"key":"e_1_2_14_385_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2019.06.042"},{"key":"e_1_2_14_386_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02122"},{"key":"e_1_2_14_387_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2021.686066"},{"key":"e_1_2_14_388_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-020-0344-4"},{"key":"e_1_2_14_389_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.385843"},{"key":"e_1_2_14_390_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00508"},{"key":"e_1_2_14_391_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.14290"},{"key":"e_1_2_14_392_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29369"},{"key":"e_1_2_14_393_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)01655-5"},{"key":"e_1_2_14_394_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-021-05585-2"},{"key":"e_1_2_14_395_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13577-023-00905-7"},{"key":"e_1_2_14_396_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-024-06349-4"},{"key":"e_1_2_14_397_1","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.3483"},{"key":"e_1_2_14_398_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2023.1076690"},{"key":"e_1_2_14_399_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2019.0943"},{"key":"e_1_2_14_400_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0170639"},{"key":"e_1_2_14_401_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25031674"},{"key":"e_1_2_14_402_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.202451664"},{"key":"e_1_2_14_403_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b01005"},{"key":"e_1_2_14_404_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.1087260"},{"key":"e_1_2_14_405_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-023-00807-x"},{"key":"e_1_2_14_406_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-023-00754-7"},{"key":"e_1_2_14_407_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.997018"},{"key":"e_1_2_14_408_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00579-3"},{"key":"e_1_2_14_409_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.31031"},{"key":"e_1_2_14_410_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1292679"},{"key":"e_1_2_14_411_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24486"},{"key":"e_1_2_14_412_1","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2020.0261"},{"key":"e_1_2_14_413_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.05.041"},{"key":"e_1_2_14_414_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2023.108353"},{"key":"e_1_2_14_415_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.05.008"}],"container-title":["MedComm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mco2.70390","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T08:16:26Z","timestamp":1763712986000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mco2.70390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,18]]},"references-count":414,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1002\/mco2.70390"],"URL":"https:\/\/doi.org\/10.1002\/mco2.70390","archive":["Portico"],"relation":{},"ISSN":["2688-2663","2688-2663"],"issn-type":[{"value":"2688-2663","type":"print"},{"value":"2688-2663","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,18]]},"article-number":"e70390"}}