{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T06:16:47Z","timestamp":1783491407812,"version":"3.55.0"},"reference-count":37,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82161138020"],"award-info":[{"award-number":["82161138020"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MedComm"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>The trends in allergic comorbidities secondary to the environmental variations in China remain unclear. We aimed to determine the variation of allergic comorbidities and polysensitization among asthma and\/or rhinitis patients in the past decade. We assessed two nationally representative cross\u2010sectional datasets from 2008 to 2009 and 2018 to 2019, which enrolled 2322 and 2353 patients, respectively. Over the present 10\u2010year study period, the prevalence of allergic symptoms and allergen sensitivity among patients with multiple sensitivities in the 2018\u20132019 cohort was significantly higher than that in the 2008\u20132009 cohort, especially for mites, pollen, and animal allergens. The comorbidity rates of asthma, allergic rhinitis, conjunctivitis, and eczema were significantly increased in the 2018\u20132019 cohort. Also in that cohort, IgE polysensitization was significantly associated with the coexistence of asthma and rhinitis, and the number of IgE\u2010reactive allergens was significantly associated with the number of multimorbidities. Use of an air\u2010conditioner and carpet in the home, and keeping pet were linked to the risk of polysensitization. Our findings suggest an increase in the comorbidity rate and multimorbid polysensitized phenotype of allergic diseases in China. Asthma occurred in both cohorts more frequently with coexisting allergies than as a single entity.<\/jats:p>","DOI":"10.1002\/mco2.70762","type":"journal-article","created":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T06:41:38Z","timestamp":1780641698000},"source":"Crossref","is-referenced-by-count":0,"title":["Trends in Asthma\u2010Rhinitis Allergic Multimorbidity and Polysensitization in China: The CARRAD Study"],"prefix":"10.1002","volume":"7","author":[{"given":"Wanjun","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Allergy and Clinical Immunology National Clinical Research Center for Respiratory Disease State Key Laboratory of Respiratory Disease Guangzhou Institute of Respiratory Health The First Affiliated Hospital of Guangzhou Medical University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhong","family":"Wang","sequence":"additional","affiliation":[{"name":"The First People's Hospital of Yibin  Yibin 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