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However, its reduced efficacy compared with EGFR\u2010mutant adenocarcinoma highlights the need for histology\u2010specific therapeutic strategies.<\/jats:p>\n                  <jats:p>\n                    <jats:bold>Trial Registration<\/jats:bold>\n                    : NCT04354961\n                  <\/jats:p>","DOI":"10.1002\/mco2.70855","type":"journal-article","created":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T11:56:47Z","timestamp":1784721407000},"source":"Crossref","is-referenced-by-count":0,"title":["Safety and Efficacy of Aumolertinib as First\u2010Line Treatment in EGFR\u2010Mutant Lung Adenosquamous Carcinoma: A Multicenter, Single\u2010Arm, Prospective Phase II Study (ARISE Study)"],"prefix":"10.1002","volume":"7","author":[{"given":"Longfeng","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Thoracic Oncology Clinical Oncology School of Fujian Medical University Fujian Cancer Hospital  Fuzhou Fujian 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