{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:45:56Z","timestamp":1792043156765,"version":"4.4.0"},"reference-count":36,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MedComm"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Postoperative follow\u2010up for patients with implantable cardioverter\u2010defibrillators and cardiac resynchronization therapy defibrillators (ICD\/CRT\u2010D) is often delayed in remote areas because of geographic barriers and limited healthcare resources, increasing the risk of adverse outcomes. The \u201cMake Changes\u201d study, was a prospective, multicenter, open\u2010label randomized trial evaluating a 5G\u2010cloud technology platform (5G\u2010CTP) for real\u2010time remote device interrogation and reprogramming versus standard In\u2010clinic care. Between October 2022 and February 2024, 206 patients from five centers were randomly assigned to 12 months of follow\u2010up with 5G\u2010CTP (\n                    <jats:italic>n<\/jats:italic>\n                    = 104) or In\u2010clinic care (\n                    <jats:italic>n<\/jats:italic>\n                    = 102). For the primary endpoint of time from clinical event to intervention, the 5G\u2010CTP group had a significantly shorter response time than the In\u2010Clinic group (4.2\u00a0vs. 11.5 days; p\u00a0&lt;\u00a00.001). For secondary endpoints, the 5G\u2010CTP group showed greater improvement in life quality at 12 months based on Minnesota Living with Heart Failure Questionnaire (\n                    <jats:italic>p<\/jats:italic>\n                    = 0.012). Rates of unplanned visits and clinical interventions were similar between groups, with no procedure\u2010related complications. This model integrates community hospitals with implantation centers through 5G networks, enabling timely specialist\u2010directed care locally without long\u2010distance travel. It is a feasible strategy for postoperative ICD\/CRT\u2010D management, particularly in underserved regions with limited access to specialized cardiac care.\n                  <\/jats:p>","DOI":"10.1002\/mco2.71037","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T07:06:40Z","timestamp":1790665600000},"source":"Crossref","is-referenced-by-count":0,"title":["5G Cloud\u2010Enabled Telemedicine for Remote Management of Heart Failure Patients With Implantable Cardioverter\u2010Defibrillators: A Multicenter Open\u2010Label Randomized Controlled Trial"],"prefix":"10.1002","volume":"7","author":[{"given":"Pan","family":"Li","sequence":"first","affiliation":[{"name":"Department of Cardiology Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fayuan","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Union Hospital Fujian Medical University  Fuzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiding","family":"Qi","sequence":"additional","affiliation":[{"name":"Department of Cardiology Shanghai Chest Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianxian","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Cardiology Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyi","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Health Statistics Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinghua","family":"Shan","sequence":"additional","affiliation":[{"name":"Department of Cardiology Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Cardiology PLA Navy No. 971 Hospital  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guowei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Xinjiang Military Region General Hospital  Urumqi China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingjuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Shanghai Chest Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bo","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Cardiology Changhai Hospital Naval Medical University  Shanghai China"},{"name":"Department of Cardiology Xinhua Hospital Shanghai Jiao Tong University School of Medicine  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifu","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Cardiology Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongkai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Cardiology Changhai Hospital Naval Medical University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq337"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043399"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050496"},{"issue":"21","key":"e_1_2_13_5_1","first-page":"e350","article-title":"ACC\/AHA\/HRS 2008 Guidelines for Device\u2010Based Therapy of Cardiac Rhythm Abnormalities: A Report of the American College of Cardiology\/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the ACC\/AHA\/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices): Developed in Collaboration With the American Association for Thoracic Surgery and Society of Thoracic Surgeons","volume":"117","author":"Epstein A. 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