{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T05:46:23Z","timestamp":1792043183462,"version":"4.4.0"},"reference-count":335,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T00:00:00Z","timestamp":1791072000000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82573874"],"award-info":[{"award-number":["82573874"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81802362"],"award-info":[{"award-number":["81802362"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82303398"],"award-info":[{"award-number":["82303398"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["MedComm"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Immune\u2010cell dynamics within the tumor microenvironment (TME) determine whether immune cells can reach, recognize, and sustain antitumor function against malignant cells under suppressive pressure. These dynamics are shaped by hypoxia, nutrient stress, cytokine and chemokine signaling, stromal architecture, vascular access, and multicellular crosstalk, and are further regulated by transcriptional and epigenetic programs. In this review, we organize TME immunity around four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, failure to sustain effector function, and suppressive tissue remodeling. We use FOSL2\/Fra\u20102, a component of activator protein\u20101 (AP\u20101) transcription factor complexes, as an example of how local signals can produce distinct regulatory effects in malignant, immune, and stromal compartments. FOSL2\u2010associated programs have been linked to differentiation, plasticity, myeloid and stromal remodeling, stress adaptation, and selected immune\u2010regulatory processes; however, the strength and direction of these associations vary by lineage, tumor type, model system, and level of functional evidence. We distinguish perturbation\u2010supported mechanisms from correlative state signatures and identify the need for spatial validation, functional perturbation, and biomarker validation. This perspective supports biomarker\u2010guided TME\u2010directed therapy matched to the dominant immune barrier.<\/jats:p>","DOI":"10.1002\/mco2.71040","type":"journal-article","created":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T07:55:27Z","timestamp":1791100527000},"source":"Crossref","is-referenced-by-count":0,"title":["Immune\u2010Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy"],"prefix":"10.1002","volume":"7","author":[{"given":"Pin","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Neurosurgery The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhao","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Department of Oncology Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Shanghai Jiao Tong University School of Medicine Affiliated Renji Hospital and School of Biomedical Engineering  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengdi","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Department of Oncology Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Cancer Center Zhejiang Provincial People's Hospital (Affiliated People's Hospital), Hangzhou Medical College  Hangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Guan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zechen","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery The Affiliated Hospital of Qingdao University  Qingdao China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases Mayo Clinic  Rochester New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3231-3576","authenticated-orcid":false,"given":"Guang\u2010Liang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Department of Oncology Fudan University Shanghai Cancer Center, Shanghai Medical College, Fudan University  Shanghai China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,4]]},"reference":[{"key":"e_1_2_18_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-023-00560-y"},{"key":"e_1_2_18_3_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-1507"},{"key":"e_1_2_18_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2023.05.036"},{"key":"e_1_2_18_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02518-x"},{"key":"e_1_2_18_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40164-025-00689-6"},{"key":"e_1_2_18_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0014-x"},{"key":"e_1_2_18_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2023.101177"},{"key":"e_1_2_18_9_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.173712"},{"key":"e_1_2_18_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-004410"},{"key":"e_1_2_18_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc4029"},{"key":"e_1_2_18_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2025.12.010"},{"key":"e_1_2_18_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1209"},{"key":"e_1_2_18_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.9.3619"},{"key":"e_1_2_18_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb0502-e131"},{"key":"e_1_2_18_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14061480"},{"key":"e_1_2_18_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1224892"},{"key":"e_1_2_18_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.20.5537"},{"key":"e_1_2_18_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.13.12.7429-7438.1993"},{"issue":"3","key":"e_1_2_18_20_1","first-page":"921","article-title":"Fos Family Members: Regulation, Structure and Role in Oncogenic Transformation","volume":"15","author":"Tulchinsky E.","year":"2000","journal-title":"Histology and Histopathology"},{"key":"e_1_2_18_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-023-01248-4"},{"key":"e_1_2_18_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature07019"},{"key":"e_1_2_18_23_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.01414"},{"key":"e_1_2_18_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-020-00660-4"},{"key":"e_1_2_18_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.909270"},{"key":"e_1_2_18_26_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20160514"},{"key":"e_1_2_18_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.09.016"},{"key":"e_1_2_18_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2019.109408"},{"issue":"18","key":"e_1_2_18_29_1","article-title":"Liver Cancer Development Driven by the AP\u20101\/c\u2010Jun\u223cFra\u20102 Dimer Through c\u2010Myc","volume":"121","author":"Bakiri L.","year":"2024","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"e_1_2_18_30_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.55074"},{"key":"e_1_2_18_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-023-01734-w"},{"key":"e_1_2_18_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2023.216145"},{"key":"e_1_2_18_33_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.104.006023"},{"key":"e_1_2_18_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2017.11.007"},{"key":"e_1_2_18_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2021.01.012"},{"key":"e_1_2_18_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature25501"},{"key":"e_1_2_18_37_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-91287-5_27"},{"key":"e_1_2_18_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.887380"},{"key":"e_1_2_18_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acr.2015.05.001"},{"key":"e_1_2_18_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-025-01187-w"},{"key":"e_1_2_18_41_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa6204"},{"key":"e_1_2_18_42_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-041015-055523"},{"key":"e_1_2_18_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2023.102329"},{"key":"e_1_2_18_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02280-1"},{"key":"e_1_2_18_45_1","doi-asserted-by":"publisher","DOI":"10.4049\/immunohorizons.1900017"},{"key":"e_1_2_18_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44318-024-00319-7"},{"key":"e_1_2_18_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2014.09.006"},{"key":"e_1_2_18_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-023-00990-6"},{"key":"e_1_2_18_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/cac2.12596"},{"key":"e_1_2_18_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21113930"},{"key":"e_1_2_18_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2023.01.009"},{"key":"e_1_2_18_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2018.03.012"},{"key":"e_1_2_18_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2016.05.002"},{"key":"e_1_2_18_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13608"},{"key":"e_1_2_18_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00574-3"},{"key":"e_1_2_18_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2023.11.005"},{"key":"e_1_2_18_57_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2022-004605"},{"key":"e_1_2_18_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.07.011"},{"key":"e_1_2_18_59_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M109.047423"},{"key":"e_1_2_18_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jncc.2023.09.001"},{"key":"e_1_2_18_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-14987-6"},{"key":"e_1_2_18_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-025-02566-x"},{"key":"e_1_2_18_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.02.020"},{"key":"e_1_2_18_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01267-2"},{"key":"e_1_2_18_65_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-15-0012"},{"key":"e_1_2_18_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02242-7"},{"key":"e_1_2_18_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2025.07.014"},{"key":"e_1_2_18_68_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.785222"},{"key":"e_1_2_18_69_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-024-02064-1"},{"key":"e_1_2_18_70_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.766275"},{"key":"e_1_2_18_71_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-23-1380"},{"key":"e_1_2_18_72_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3003299"},{"key":"e_1_2_18_73_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-021-01103-4"},{"key":"e_1_2_18_74_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2024-332901"},{"key":"e_1_2_18_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.08.003"},{"key":"e_1_2_18_76_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2024-011380"},{"key":"e_1_2_18_77_1","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2018.195396"},{"key":"e_1_2_18_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-019-0444-9"},{"key":"e_1_2_18_79_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-22-0196"},{"key":"e_1_2_18_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-025-01697-8"},{"key":"e_1_2_18_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.11.006"},{"key":"e_1_2_18_82_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.933113"},{"key":"e_1_2_18_83_1","first-page":"7","article-title":"Metabolic Crossroads: Unravelling Immune Cell Dynamics in Gastrointestinal Cancer Drug Resistance","volume":"8","author":"Suri C.","year":"2025","journal-title":"Cancer Drug Resistance"},{"key":"e_1_2_18_84_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2021-003521"},{"key":"e_1_2_18_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2023.06.003"},{"key":"e_1_2_18_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11670-012-0130-y"},{"key":"e_1_2_18_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-020-01145-4"},{"key":"e_1_2_18_88_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1549276"},{"key":"e_1_2_18_89_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI128895"},{"key":"e_1_2_18_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31764-9"},{"key":"e_1_2_18_91_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21771"},{"key":"e_1_2_18_92_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-024-01564-3"},{"key":"e_1_2_18_93_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI84430"},{"key":"e_1_2_18_94_1","doi-asserted-by":"publisher","DOI":"10.48101\/ujms.v126.10710"},{"issue":"4","key":"e_1_2_18_95_1","first-page":"1091","article-title":"CAFs Vs. TECs: When Blood Feuds Fuel Cancer Progression, Dissemination and Therapeutic Resistance","volume":"47","author":"Coursier D.","year":"2024","journal-title":"Cellular Oncology (Dordrecht, Netherlands)"},{"key":"e_1_2_18_96_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6283796"},{"issue":"9","key":"e_1_2_18_97_1","first-page":"763","article-title":"Classifying the Linkage Between Adipose Tissue Inflammation and Tumor Growth Through Cancer\u2010Associated Adipocytes","volume":"43","author":"Song Y. C.","year":"2020","journal-title":"Molecules and Cells"},{"issue":"8","key":"e_1_2_18_98_1","first-page":"3777","article-title":"Role of Hypoxia in Inhibiting Dendritic Cells by VEGF Signaling in Tumor Microenvironments: Mechanism and Application","volume":"11","author":"Han Z.","year":"2021","journal-title":"American Journal of Cancer Research"},{"key":"e_1_2_18_99_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-23-2352"},{"key":"e_1_2_18_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2025.02.022"},{"key":"e_1_2_18_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2024.217060"},{"key":"e_1_2_18_102_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-021-01133-y"},{"key":"e_1_2_18_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jncc.2025.03.002"},{"key":"e_1_2_18_104_1","first-page":"29","article-title":"Augmenting Antitumor Immune Responses With Epigenetic Modifying Agents","volume":"6","author":"H\u00e9ninger E.","year":"2015","journal-title":"Frontiers in Immunology"},{"key":"e_1_2_18_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2023.04.040"},{"key":"e_1_2_18_106_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells13151281"},{"key":"e_1_2_18_107_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-2125"},{"key":"e_1_2_18_108_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0266-5"},{"key":"e_1_2_18_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2017.117"},{"key":"e_1_2_18_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2025.117043"},{"key":"e_1_2_18_111_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-1942"},{"key":"e_1_2_18_112_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1606508"},{"key":"e_1_2_18_113_1","first-page":"303","article-title":"Bridging Innate and Adaptive Tumor Immunity: CGAS\u2013STING Pathway Activation to Potentiate Immune Checkpoint Blockade","volume":"44","author":"Li Z.","year":"2025","journal-title":"Journal of Experimental & Clinical Cancer Research CR"},{"key":"e_1_2_18_114_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-025-01691-5"},{"key":"e_1_2_18_115_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-55330-7"},{"key":"e_1_2_18_116_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-025-02521-5"},{"key":"e_1_2_18_117_1","first-page":"341","article-title":"Microbiota Boost Immunotherapy? A Meta\u2010Analysis Dives Into Fecal Microbiota Transplantation and Immune Checkpoint Inhibitors","volume":"23","author":"Lin A.","year":"2025","journal-title":"BMC Medicine [Electronic Resource]"},{"key":"e_1_2_18_118_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-025-09249-8"},{"key":"e_1_2_18_119_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abq4006"},{"key":"e_1_2_18_120_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12929-025-01208-9"},{"key":"e_1_2_18_121_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-025-01212-6"},{"key":"e_1_2_18_122_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-025-01041-3"},{"key":"e_1_2_18_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2008.02.001"},{"key":"e_1_2_18_124_1","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46456-0"},{"key":"e_1_2_18_125_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-023-00431-8"},{"key":"e_1_2_18_126_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-023-02313-y"},{"key":"e_1_2_18_127_1","doi-asserted-by":"publisher","DOI":"10.1080\/15384047.2023.2223377"},{"key":"e_1_2_18_128_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201948796"},{"key":"e_1_2_18_129_1","first-page":"260","article-title":"Integration of ATAC\u2010Seq and RNA\u2010Seq Reveals FOSL2 Drives Human Liver Progenitor\u2010Like Cell Aging by Regulating Inflammatory Factors","volume":"24","author":"Ding M.","year":"2023","journal-title":"BMC Genomics [Electronic Resource]"},{"key":"e_1_2_18_130_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.19.11453"},{"key":"e_1_2_18_131_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2025.08.002"},{"key":"e_1_2_18_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2024.04.004"},{"key":"e_1_2_18_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02371-y"},{"key":"e_1_2_18_134_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.702726"},{"key":"e_1_2_18_135_1","doi-asserted-by":"publisher","DOI":"10.4110\/in.2020.20.e4"},{"key":"e_1_2_18_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.108469"},{"key":"e_1_2_18_137_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.643298"},{"key":"e_1_2_18_138_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsptsci.4c00156"},{"key":"e_1_2_18_139_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2376"},{"key":"e_1_2_18_140_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1093"},{"key":"e_1_2_18_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.02.021"},{"key":"e_1_2_18_142_1","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0000000000001256"},{"key":"e_1_2_18_143_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1621280114"},{"key":"e_1_2_18_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2019.05.009"},{"key":"e_1_2_18_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10169"},{"key":"e_1_2_18_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2024.101479"},{"issue":"1","key":"e_1_2_18_147_1","first-page":"3","article-title":"CXCL9 Secreted by Tumor\u2010Associated Dendritic Cells Up\u2010Regulates PD\u2010L1 Expression in Bladder Cancer Cells by Activating the CXCR3 Signaling","volume":"22","author":"Xiu W.","year":"2021","journal-title":"BMC Immunology [Electronic Resource]"},{"key":"e_1_2_18_148_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-018-2161-9"},{"key":"e_1_2_18_149_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00500"},{"key":"e_1_2_18_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2014.02.016"},{"key":"e_1_2_18_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2022.07.002"},{"key":"e_1_2_18_152_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-2325"},{"issue":"3","key":"e_1_2_18_153_1","first-page":"881","article-title":"The Contribution of Vascular Endothelial Growth Factor to the Induction of Regulatory T\u2010Cells in Malignant Effusions","volume":"29","author":"Wada J.","year":"2009","journal-title":"Anticancer Research"},{"key":"e_1_2_18_154_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40425-018-0403-1"},{"key":"e_1_2_18_155_1","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201041093"},{"key":"e_1_2_18_156_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-16312-x"},{"key":"e_1_2_18_157_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-025-01688-0"},{"key":"e_1_2_18_158_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26352-2"},{"issue":"2","key":"e_1_2_18_159_1","first-page":"623","article-title":"Adenosine A2a Receptor Signals Inhibit Germinal Center T Follicular Helper Cell Differentiation During the Primary Response to Vaccination","volume":"198","author":"Schmiel S. E.","year":"2016","journal-title":"Journal of Immunology Baltimore Md 1950"},{"key":"e_1_2_18_160_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1817652116"},{"key":"e_1_2_18_161_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2019104063"},{"key":"e_1_2_18_162_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.605619"},{"key":"e_1_2_18_163_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf9419"},{"key":"e_1_2_18_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-020-02792-5"},{"key":"e_1_2_18_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2021.109422"},{"key":"e_1_2_18_166_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI139905"},{"key":"e_1_2_18_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2022.12.007"},{"key":"e_1_2_18_168_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29753-z"},{"key":"e_1_2_18_169_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-025-07557-5"},{"key":"e_1_2_18_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.05.027"},{"key":"e_1_2_18_171_1","doi-asserted-by":"publisher","DOI":"10.1002\/JLB.6MR0320-234R"},{"key":"e_1_2_18_172_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-024-00969-w"},{"key":"e_1_2_18_173_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01337-5"},{"key":"e_1_2_18_174_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adg1094"},{"key":"e_1_2_18_175_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-019-0235-4"},{"key":"e_1_2_18_176_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-0760-z"},{"key":"e_1_2_18_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1324-y"},{"key":"e_1_2_18_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.10.029"},{"key":"e_1_2_18_179_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2022.03.005"},{"key":"e_1_2_18_180_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11824"},{"key":"e_1_2_18_181_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-018-0589-3"},{"key":"e_1_2_18_182_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20201963"},{"issue":"2","key":"e_1_2_18_183_1","first-page":"415","article-title":"Unlocking the Complexities of Tumor\u2010Associated Regulatory T Cells","volume":"200","author":"Chao J. L.","year":"2018","journal-title":"Journal of Immunology Baltimore Md 1950"},{"key":"e_1_2_18_184_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0050080"},{"key":"e_1_2_18_185_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01170-w"},{"key":"e_1_2_18_186_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2025.110021"},{"issue":"7","key":"e_1_2_18_187_1","first-page":"3433","article-title":"Expression of Helios, an Ikaros Transcription Factor Family Member, Differentiates Thymic\u2010Derived From Peripherally Induced Foxp3+ T Regulatory Cells","volume":"184","author":"Am T.","year":"2010","journal-title":"Journal of Immunology Baltimore Md 1950"},{"key":"e_1_2_18_188_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.10.021"},{"key":"e_1_2_18_189_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.05.035"},{"key":"e_1_2_18_190_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-47981-3"},{"key":"e_1_2_18_191_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20232068"},{"key":"e_1_2_18_192_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.114681"},{"key":"e_1_2_18_193_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2024.107297"},{"key":"e_1_2_18_194_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2024-009435"},{"key":"e_1_2_18_195_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1507283"},{"key":"e_1_2_18_196_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-025-03517-1"},{"key":"e_1_2_18_197_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1198551"},{"key":"e_1_2_18_198_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2020.04.014"},{"key":"e_1_2_18_199_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adg3868"},{"key":"e_1_2_18_200_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-20-0637"},{"key":"e_1_2_18_201_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1379376"},{"key":"e_1_2_18_202_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1409238"},{"key":"e_1_2_18_203_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.06.007"},{"issue":"1","key":"e_1_2_18_204_1","first-page":"82","article-title":"The Loss of TET2 Promotes CD8+ T Cell Memory Differentiation","volume":"200","author":"Carty S. A.","year":"2018","journal-title":"Journal of immunology Baltimore Md 1950"},{"key":"e_1_2_18_205_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adp9371"},{"key":"e_1_2_18_206_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-00975-5"},{"key":"e_1_2_18_207_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-00979-1"},{"key":"e_1_2_18_208_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1202947"},{"key":"e_1_2_18_209_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2023739118"},{"key":"e_1_2_18_210_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2013.06.006"},{"key":"e_1_2_18_211_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-020-00133-0"},{"key":"e_1_2_18_212_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02839"},{"key":"e_1_2_18_213_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1729690"},{"key":"e_1_2_18_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2023.04.003"},{"key":"e_1_2_18_215_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac256"},{"key":"e_1_2_18_216_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.05.013"},{"key":"e_1_2_18_217_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.1c03681"},{"key":"e_1_2_18_218_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.04.015"},{"key":"e_1_2_18_219_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.04.038"},{"key":"e_1_2_18_220_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.107826"},{"key":"e_1_2_18_221_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2017.102"},{"issue":"5","key":"e_1_2_18_222_1","first-page":"2284","article-title":"Adenosine Promotes Foxp3 Expression in Treg Cells in Sepsis Model by Activating JNK\/AP\u20101 Pathway","volume":"8","author":"Bao R.","year":"2016","journal-title":"American Journal of Translational Research"},{"key":"e_1_2_18_223_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-023-04746-3"},{"key":"e_1_2_18_224_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00380-3"},{"key":"e_1_2_18_225_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.6.3648"},{"key":"e_1_2_18_226_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.xcrm.2022.100744"},{"key":"e_1_2_18_227_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2023.02.017"},{"key":"e_1_2_18_228_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adj4857"},{"key":"e_1_2_18_229_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-021-00232-6"},{"key":"e_1_2_18_230_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46873-w"},{"key":"e_1_2_18_231_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-024-03936-7"},{"key":"e_1_2_18_232_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-23-0193"},{"key":"e_1_2_18_233_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-022-00466-1"},{"key":"e_1_2_18_234_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2931-3"},{"key":"e_1_2_18_235_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.02.012"},{"key":"e_1_2_18_236_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-019-02449-y"},{"key":"e_1_2_18_237_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2022.03.011"},{"key":"e_1_2_18_238_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-023-01060-7"},{"key":"e_1_2_18_239_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adp1865"},{"key":"e_1_2_18_240_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13568"},{"key":"e_1_2_18_241_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0257-x"},{"key":"e_1_2_18_242_1","doi-asserted-by":"publisher","DOI":"10.62347\/ANSN3150"},{"key":"e_1_2_18_243_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-020-02535-6"},{"key":"e_1_2_18_244_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2017.1413520"},{"key":"e_1_2_18_245_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.201996"},{"key":"e_1_2_18_246_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omton.2024.200895"},{"key":"e_1_2_18_247_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.3800"},{"key":"e_1_2_18_248_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23239"},{"key":"e_1_2_18_249_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-1440"},{"key":"e_1_2_18_250_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-014-1629-5"},{"key":"e_1_2_18_251_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-21-0435"},{"key":"e_1_2_18_252_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.01.004"},{"key":"e_1_2_18_253_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24031933"},{"key":"e_1_2_18_254_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15184616"},{"key":"e_1_2_18_255_1","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.4243"},{"key":"e_1_2_18_256_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-025-02178-8"},{"key":"e_1_2_18_257_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-23-0334"},{"key":"e_1_2_18_258_1","doi-asserted-by":"publisher","DOI":"10.1093\/jleuko\/qiaf011"},{"key":"e_1_2_18_259_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2101169118"},{"key":"e_1_2_18_260_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-61196-0"},{"key":"e_1_2_18_261_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abn6563"},{"key":"e_1_2_18_262_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1286750"},{"key":"e_1_2_18_263_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.7.2067"},{"key":"e_1_2_18_264_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00561-z"},{"key":"e_1_2_18_265_1","doi-asserted-by":"publisher","DOI":"10.1158\/2767-9764.CRC-23-0203"},{"key":"e_1_2_18_266_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2025.117964"},{"key":"e_1_2_18_267_1","doi-asserted-by":"publisher","DOI":"10.4161\/epi.19373"},{"key":"e_1_2_18_268_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1051045"},{"key":"e_1_2_18_269_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-23-0448"},{"key":"e_1_2_18_270_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06372-1"},{"key":"e_1_2_18_271_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2017.09.016"},{"issue":"4","key":"e_1_2_18_272_1","first-page":"2575","article-title":"Aberrant Selection and Function of Invariant NKT Cells in the Absence of AP\u20101 Transcription Factor Fra\u20102","volume":"183","author":"Lawson V. J.","year":"2009","journal-title":"Journal of Immunology Baltimore Md 1950"},{"key":"e_1_2_18_273_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpb.2020.12.003"},{"key":"e_1_2_18_274_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2022.166534"},{"key":"e_1_2_18_275_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2022.04.008"},{"key":"e_1_2_18_276_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2023.10.007"},{"key":"e_1_2_18_277_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-024-01887-6"},{"key":"e_1_2_18_278_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.ade2292"},{"key":"e_1_2_18_279_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2025.112498"},{"key":"e_1_2_18_280_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-24-0791"},{"key":"e_1_2_18_281_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41698-024-00660-4"},{"key":"e_1_2_18_282_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2024-009602"},{"key":"e_1_2_18_283_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.113746"},{"key":"e_1_2_18_284_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abi8602"},{"key":"e_1_2_18_285_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-61560-0"},{"key":"e_1_2_18_286_1","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.14998"},{"key":"e_1_2_18_287_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2102434118"},{"key":"e_1_2_18_288_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2022.110609"},{"key":"e_1_2_18_289_1","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2022-006020"},{"key":"e_1_2_18_290_1","doi-asserted-by":"publisher","DOI":"10.21037\/tlcr-2025-912"},{"key":"e_1_2_18_291_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12307-012-0113-z"},{"key":"e_1_2_18_292_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-24-0589"},{"key":"e_1_2_18_293_1","doi-asserted-by":"crossref","unstructured":"S.Mayer T.Milo A.Isaacson et\u00a0al. \u201cA Cell Circuit Approach to Dissect Fibroblast\u2010Macrophage Interactions in the Tumor Microenvironment \u201d preprint bioRxiv November 17 2022:2022.11.17.516850.","DOI":"10.1101\/2022.11.17.516850"},{"key":"e_1_2_18_294_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11538-025-01466-6"},{"key":"e_1_2_18_295_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.14521"},{"key":"e_1_2_18_296_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-025-06235-6"},{"issue":"24","key":"e_1_2_18_297_1","first-page":"8794","article-title":"The Dynamics of the T\u2010Cell Antitumor Response: Chemokine\u2010Secreting Dendritic Cells Can Prime Tumor\u2010Reactive T Cells Extranodally","volume":"61","author":"Kirk C. J.","year":"2001","journal-title":"Cancer Research"},{"key":"e_1_2_18_298_1","doi-asserted-by":"crossref","unstructured":"V. P.Schuster K.Brown J. R.Unsworth N.Berkowitz andM. K.Ruhland \u201cContextual Control of CD8+ T Cell Priming by Dendritic Cell Subsets in Tumor and Inflammatory Microenvironments \u201d preprint bioRxiv: The Preprint Server for Biology posted online November 3 2025:2025.10.31.685861.","DOI":"10.1016\/j.celrep.2026.118070"},{"key":"e_1_2_18_299_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.04.016"},{"key":"e_1_2_18_300_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.add3955"},{"key":"e_1_2_18_301_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41389-022-00438-y"},{"key":"e_1_2_18_302_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.abm9409"},{"key":"e_1_2_18_303_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-23-0666"},{"key":"e_1_2_18_304_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16122211"},{"key":"e_1_2_18_305_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.79957"},{"key":"e_1_2_18_306_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02345-0"},{"key":"e_1_2_18_307_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09416-2"},{"key":"e_1_2_18_308_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-020-0281-y"},{"key":"e_1_2_18_309_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI143759"},{"key":"e_1_2_18_310_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.02.005"},{"key":"e_1_2_18_311_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05400-x"},{"key":"e_1_2_18_312_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2024.10.010"},{"key":"e_1_2_18_313_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20241957"},{"key":"e_1_2_18_314_1","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202507167"},{"key":"e_1_2_18_315_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.734188"},{"key":"e_1_2_18_316_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01740-4"},{"key":"e_1_2_18_317_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-024-04771-7"},{"key":"e_1_2_18_318_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaz6105"},{"key":"e_1_2_18_319_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-49916-4"},{"key":"e_1_2_18_320_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-025-02419-0"},{"key":"e_1_2_18_321_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02018"},{"key":"e_1_2_18_322_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00505.2020"},{"key":"e_1_2_18_323_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-06186-8"},{"key":"e_1_2_18_324_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-022-01585-z"},{"issue":"7","key":"e_1_2_18_325_1","first-page":"1081","article-title":"Fosl2 Deficiency Predisposes Mice to Osteopetrosis, Leading to Bone Marrow Failure","volume":"212","author":"Chen J.","year":"2024","journal-title":"Journal of Immunology Baltimore Md 1950"},{"key":"e_1_2_18_326_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2012.08.004"},{"key":"e_1_2_18_327_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-45308-w"},{"key":"e_1_2_18_328_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.11.4972"},{"key":"e_1_2_18_329_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3940(00)01748-1"},{"key":"e_1_2_18_330_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112164"},{"key":"e_1_2_18_331_1","doi-asserted-by":"publisher","DOI":"10.1134\/S000635092006010X"},{"key":"e_1_2_18_332_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2107507118"},{"key":"e_1_2_18_333_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2022.101342"},{"key":"e_1_2_18_334_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.897750"},{"key":"e_1_2_18_335_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04057-2"},{"key":"e_1_2_18_336_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-024-01026-4"}],"container-title":["MedComm"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mco2.71040","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/mco2.71040","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/mco2.71040","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:58:50Z","timestamp":1792040330000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/mco2.71040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":335,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1002\/mco2.71040"],"URL":"https:\/\/doi.org\/10.1002\/mco2.71040","archive":["Portico"],"relation":{},"ISSN":["2688-2663","2688-2663"],"issn-type":[{"value":"2688-2663","type":"print"},{"value":"2688-2663","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10]]},"article-number":"e71040"}}